Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS_AND_ASSEMBLY |
| Enrichment Score (ES) | -0.6105286 |
| Normalized Enrichment Score (NES) | -2.0122135 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006365351 |
| FWER p-Value | 0.106 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EIF2B2 | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 975 | 0.149 | -0.0358 | No |
| 2 | EIF2AK3 | EIF2AK3 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 3 | 2812 | 0.060 | -0.1587 | No |
| 3 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 4466 | 0.024 | -0.2769 | No |
| 4 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 4725 | 0.020 | -0.2914 | No |
| 5 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 7219 | -0.018 | -0.4741 | No |
| 6 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 7294 | -0.019 | -0.4747 | No |
| 7 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7495 | -0.022 | -0.4842 | No |
| 8 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 7792 | -0.027 | -0.4995 | No |
| 9 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7935 | -0.030 | -0.5027 | No |
| 10 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7939 | -0.030 | -0.4955 | No |
| 11 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 8143 | -0.033 | -0.5025 | No |
| 12 | SLU7 | SLU7 Entrez, Source | - | 8831 | -0.044 | -0.5429 | No |
| 13 | EIF5 | EIF5 Entrez, Source | eukaryotic translation initiation factor 5 | 9653 | -0.059 | -0.5898 | Yes |
| 14 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 9796 | -0.062 | -0.5849 | Yes |
| 15 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 9841 | -0.063 | -0.5724 | Yes |
| 16 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 10057 | -0.068 | -0.5715 | Yes |
| 17 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 10424 | -0.075 | -0.5801 | Yes |
| 18 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 10600 | -0.080 | -0.5732 | Yes |
| 19 | EIF2B3 | EIF2B3 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 11098 | -0.093 | -0.5871 | Yes |
| 20 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11229 | -0.096 | -0.5726 | Yes |
| 21 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 11294 | -0.098 | -0.5526 | Yes |
| 22 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11540 | -0.107 | -0.5441 | Yes |
| 23 | EIF1 | EIF1 Entrez, Source | eukaryotic translation initiation factor 1 | 11662 | -0.112 | -0.5251 | Yes |
| 24 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12128 | -0.133 | -0.5266 | Yes |
| 25 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 12190 | -0.136 | -0.4970 | Yes |
| 26 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 12198 | -0.137 | -0.4631 | Yes |
| 27 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12437 | -0.150 | -0.4432 | Yes |
| 28 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12447 | -0.151 | -0.4059 | Yes |
| 29 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12500 | -0.155 | -0.3709 | Yes |
| 30 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.3322 | Yes |
| 31 | MTIF2 | MTIF2 Entrez, Source | mitochondrial translational initiation factor 2 | 12601 | -0.163 | -0.2983 | Yes |
| 32 | EIF2B5 | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 12669 | -0.170 | -0.2606 | Yes |
| 33 | FBL | FBL Entrez, Source | fibrillarin | 12880 | -0.197 | -0.2268 | Yes |
| 34 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12913 | -0.201 | -0.1785 | Yes |
| 35 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 12970 | -0.213 | -0.1291 | Yes |
| 36 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.0767 | Yes |
| 37 | SDAD1 | SDAD1 Entrez, Source | SDA1 domain containing 1 | 13284 | -0.402 | 0.0044 | Yes |
