Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | RNA_BINDING |
| Enrichment Score (ES) | -0.54541373 |
| Normalized Enrichment Score (NES) | -2.255788 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 202 | 0.385 | 0.0121 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 721 | 0.182 | -0.0142 | No |
| 3 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 847 | 0.163 | -0.0122 | No |
| 4 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 1142 | 0.133 | -0.0250 | No |
| 5 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1181 | 0.130 | -0.0187 | No |
| 6 | ZFP36 | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 1260 | 0.123 | -0.0159 | No |
| 7 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 1344 | 0.117 | -0.0139 | No |
| 8 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 2445 | 0.070 | -0.0922 | No |
| 9 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 2451 | 0.069 | -0.0877 | No |
| 10 | STAU2 | STAU2 Entrez, Source | staufen, RNA binding protein, homolog 2 (Drosophila) | 2619 | 0.064 | -0.0958 | No |
| 11 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 3097 | 0.052 | -0.1282 | No |
| 12 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 3197 | 0.050 | -0.1322 | No |
| 13 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 3661 | 0.040 | -0.1645 | No |
| 14 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 3876 | 0.035 | -0.1782 | No |
| 15 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 4046 | 0.032 | -0.1887 | No |
| 16 | DDX19B | DDX19B Entrez, Source | DEAD (Asp-Glu-Ala-As) box polypeptide 19B | 4279 | 0.028 | -0.2043 | No |
| 17 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 4575 | 0.022 | -0.2251 | No |
| 18 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 4677 | 0.020 | -0.2313 | No |
| 19 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 5026 | 0.015 | -0.2566 | No |
| 20 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 5848 | 0.002 | -0.3187 | No |
| 21 | STAU1 | STAU1 Entrez, Source | staufen, RNA binding protein, homolog 1 (Drosophila) | 5908 | 0.001 | -0.3230 | No |
| 22 | ADARB2 | ADARB2 Entrez, Source | adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) | 5942 | 0.001 | -0.3255 | No |
| 23 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 6322 | -0.005 | -0.3538 | No |
| 24 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 6403 | -0.006 | -0.3594 | No |
| 25 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6949 | -0.014 | -0.3997 | No |
| 26 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 7294 | -0.019 | -0.4244 | No |
| 27 | CIRBP | CIRBP Entrez, Source | cold inducible RNA binding protein | 7346 | -0.020 | -0.4268 | No |
| 28 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 7408 | -0.021 | -0.4299 | No |
| 29 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 7464 | -0.022 | -0.4325 | No |
| 30 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 7658 | -0.025 | -0.4454 | No |
| 31 | RTCD1 | RTCD1 Entrez, Source | RNA terminal phosphate cyclase domain 1 | 8083 | -0.032 | -0.4752 | No |
| 32 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 8143 | -0.033 | -0.4773 | No |
| 33 | TEP1 | TEP1 Entrez, Source | telomerase-associated protein 1 | 8212 | -0.034 | -0.4801 | No |
| 34 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 8242 | -0.035 | -0.4798 | No |
| 35 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.4796 | No |
| 36 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8466 | -0.038 | -0.4914 | No |
| 37 | MRPS7 | MRPS7 Entrez, Source | mitochondrial ribosomal protein S7 | 8605 | -0.041 | -0.4989 | No |
| 38 | RPL26 | RPL26 Entrez, Source | ribosomal protein L26 | 8639 | -0.041 | -0.4985 | No |
| 39 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 8663 | -0.041 | -0.4973 | No |
| 40 | RNASEL | RNASEL Entrez, Source | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | 8797 | -0.044 | -0.5043 | No |
| 41 | SLU7 | SLU7 Entrez, Source | - | 8831 | -0.044 | -0.5037 | No |
| 42 | RNASEH1 | RNASEH1 Entrez, Source | ribonuclease H1 | 8861 | -0.045 | -0.5027 | No |
| 43 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 8874 | -0.045 | -0.5004 | No |
| 44 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 8977 | -0.047 | -0.5048 | No |
| 45 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 9030 | -0.048 | -0.5053 | No |
| 46 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 9038 | -0.048 | -0.5025 | No |
| 47 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9125 | -0.049 | -0.5055 | No |
| 48 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 9249 | -0.052 | -0.5111 | No |
| 49 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 9516 | -0.056 | -0.5273 | No |
| 50 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 9579 | -0.057 | -0.5279 | No |
| 51 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 9602 | -0.058 | -0.5255 | No |
| 52 | RPS17 | RPS17 Entrez, Source | ribosomal protein S17 | 9686 | -0.060 | -0.5275 | No |
| 53 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9736 | -0.061 | -0.5269 | No |
| 54 | MRPL23 | MRPL23 Entrez, Source | mitochondrial ribosomal protein L23 | 9879 | -0.064 | -0.5331 | No |
| 55 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 9941 | -0.065 | -0.5331 | No |
| 56 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10104 | -0.068 | -0.5406 | Yes |
| 57 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 10134 | -0.069 | -0.5378 | Yes |
| 58 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 10200 | -0.071 | -0.5378 | Yes |
| 59 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 10215 | -0.071 | -0.5338 | Yes |
| 60 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 10273 | -0.072 | -0.5330 | Yes |
| 61 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 10333 | -0.073 | -0.5323 | Yes |
| 62 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 10424 | -0.075 | -0.5337 | Yes |
| 63 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 10426 | -0.075 | -0.5285 | Yes |
| 64 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 10437 | -0.076 | -0.5238 | Yes |
| 65 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 10457 | -0.077 | -0.5198 | Yes |
| 66 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 10491 | -0.078 | -0.5168 | Yes |
| 67 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 10495 | -0.078 | -0.5115 | Yes |
| 68 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10557 | -0.079 | -0.5105 | Yes |
| 69 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 10600 | -0.080 | -0.5080 | Yes |
| 70 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 10731 | -0.084 | -0.5120 | Yes |
| 71 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 10780 | -0.085 | -0.5096 | Yes |
| 72 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 10813 | -0.086 | -0.5059 | Yes |
| 73 | HNRPK | HNRPK Entrez, Source | heterogeneous nuclear ribonucleoprotein K | 10815 | -0.086 | -0.4999 | Yes |
| 74 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 10867 | -0.087 | -0.4976 | Yes |
| 75 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 10886 | -0.088 | -0.4927 | Yes |
| 76 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 10975 | -0.090 | -0.4930 | Yes |
| 77 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 11016 | -0.091 | -0.4896 | Yes |
| 78 | SUPV3L1 | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 11025 | -0.091 | -0.4837 | Yes |
| 79 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 11034 | -0.091 | -0.4778 | Yes |
| 80 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 11041 | -0.091 | -0.4718 | Yes |
| 81 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11050 | -0.092 | -0.4659 | Yes |
| 82 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 11055 | -0.092 | -0.4596 | Yes |
| 83 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 11058 | -0.092 | -0.4532 | Yes |
| 84 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11229 | -0.096 | -0.4593 | Yes |
| 85 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 11248 | -0.097 | -0.4537 | Yes |
| 86 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 11249 | -0.097 | -0.4468 | Yes |
| 87 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 11294 | -0.098 | -0.4432 | Yes |
| 88 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11346 | -0.100 | -0.4399 | Yes |
| 89 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 11351 | -0.100 | -0.4331 | Yes |
| 90 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 11388 | -0.102 | -0.4286 | Yes |
| 91 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 11396 | -0.102 | -0.4219 | Yes |
| 92 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 11401 | -0.102 | -0.4149 | Yes |
| 93 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 11460 | -0.105 | -0.4119 | Yes |
| 94 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 11478 | -0.105 | -0.4057 | Yes |
| 95 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 11505 | -0.106 | -0.4002 | Yes |
| 96 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 11507 | -0.106 | -0.3927 | Yes |
| 97 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 11511 | -0.106 | -0.3854 | Yes |
| 98 | ROD1 | ROD1 Entrez, Source | ROD1 regulator of differentiation 1 (S. pombe) | 11546 | -0.107 | -0.3803 | Yes |
| 99 | DUSP11 | DUSP11 Entrez, Source | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 11564 | -0.108 | -0.3740 | Yes |
| 100 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11569 | -0.108 | -0.3666 | Yes |
| 101 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 11571 | -0.108 | -0.3589 | Yes |
| 102 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 11672 | -0.112 | -0.3586 | Yes |
| 103 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 11779 | -0.116 | -0.3584 | Yes |
| 104 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 11843 | -0.119 | -0.3547 | Yes |
| 105 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 11863 | -0.120 | -0.3476 | Yes |
| 106 | SERBP1 | SERBP1 Entrez, Source | SERPINE1 mRNA binding protein 1 | 11903 | -0.122 | -0.3419 | Yes |
| 107 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 11961 | -0.125 | -0.3374 | Yes |
| 108 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 11970 | -0.125 | -0.3291 | Yes |
| 109 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 11991 | -0.126 | -0.3217 | Yes |
| 110 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.3214 | Yes |
| 111 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12128 | -0.133 | -0.3130 | Yes |
| 112 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 12190 | -0.136 | -0.3080 | Yes |
| 113 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 12198 | -0.137 | -0.2988 | Yes |
| 114 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 12220 | -0.137 | -0.2906 | Yes |
| 115 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12267 | -0.140 | -0.2841 | Yes |
| 116 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 12282 | -0.141 | -0.2752 | Yes |
| 117 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 12289 | -0.142 | -0.2655 | Yes |
| 118 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 12295 | -0.142 | -0.2558 | Yes |
| 119 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 12362 | -0.146 | -0.2504 | Yes |
| 120 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 12390 | -0.148 | -0.2420 | Yes |
| 121 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12406 | -0.149 | -0.2325 | Yes |
| 122 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12418 | -0.149 | -0.2228 | Yes |
| 123 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 12438 | -0.150 | -0.2135 | Yes |
| 124 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12447 | -0.151 | -0.2034 | Yes |
| 125 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12500 | -0.155 | -0.1964 | Yes |
| 126 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.1857 | Yes |
| 127 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.1777 | Yes |
| 128 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 12629 | -0.166 | -0.1719 | Yes |
| 129 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 12680 | -0.171 | -0.1635 | Yes |
| 130 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.1547 | Yes |
| 131 | HNRPH1 | HNRPH1 Entrez, Source | heterogeneous nuclear ribonucleoprotein H1 (H) | 12830 | -0.189 | -0.1488 | Yes |
| 132 | SNUPN | SNUPN Entrez, Source | snurportin 1 | 12833 | -0.189 | -0.1354 | Yes |
| 133 | FBL | FBL Entrez, Source | fibrillarin | 12880 | -0.197 | -0.1249 | Yes |
| 134 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12913 | -0.201 | -0.1130 | Yes |
| 135 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.0988 | Yes |
| 136 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12930 | -0.204 | -0.0853 | Yes |
| 137 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 12970 | -0.213 | -0.0731 | Yes |
| 138 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.0622 | Yes |
| 139 | APTX | APTX Entrez, Source | aprataxin | 13079 | -0.242 | -0.0476 | Yes |
| 140 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 13100 | -0.252 | -0.0312 | Yes |
| 141 | DAZAP1 | DAZAP1 Entrez, Source | DAZ associated protein 1 | 13172 | -0.281 | -0.0166 | Yes |
| 142 | APOBEC1 | APOBEC1 Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 13290 | -0.414 | 0.0039 | Yes |
