Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | RNA_PROCESSING |
| Enrichment Score (ES) | -0.5195647 |
| Normalized Enrichment Score (NES) | -1.9356469 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015993932 |
| FWER p-Value | 0.308 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 202 | 0.385 | 0.0376 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 721 | 0.182 | 0.0236 | No |
| 3 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 1142 | 0.133 | 0.0101 | No |
| 4 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1181 | 0.130 | 0.0251 | No |
| 5 | AGGF1 | AGGF1 Entrez, Source | angiogenic factor with G patch and FHA domains 1 | 2767 | 0.061 | -0.0860 | No |
| 6 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 3661 | 0.040 | -0.1479 | No |
| 7 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 3876 | 0.035 | -0.1592 | No |
| 8 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 4322 | 0.027 | -0.1890 | No |
| 9 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 4725 | 0.020 | -0.2166 | No |
| 10 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 5699 | 0.004 | -0.2894 | No |
| 11 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 6322 | -0.005 | -0.3356 | No |
| 12 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.3435 | No |
| 13 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 7294 | -0.019 | -0.4050 | No |
| 14 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 7464 | -0.022 | -0.4148 | No |
| 15 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7495 | -0.022 | -0.4140 | No |
| 16 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 7658 | -0.025 | -0.4227 | No |
| 17 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7935 | -0.030 | -0.4394 | No |
| 18 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7938 | -0.030 | -0.4355 | No |
| 19 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7939 | -0.030 | -0.4314 | No |
| 20 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 7988 | -0.031 | -0.4308 | No |
| 21 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 8143 | -0.033 | -0.4379 | No |
| 22 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.4429 | No |
| 23 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 8375 | -0.037 | -0.4453 | No |
| 24 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8466 | -0.038 | -0.4469 | No |
| 25 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 8663 | -0.041 | -0.4560 | No |
| 26 | INTS6 | INTS6 Entrez, Source | integrator complex subunit 6 | 8753 | -0.043 | -0.4568 | No |
| 27 | SLU7 | SLU7 Entrez, Source | - | 8831 | -0.044 | -0.4565 | No |
| 28 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 8886 | -0.045 | -0.4544 | No |
| 29 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 8977 | -0.047 | -0.4547 | No |
| 30 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 9038 | -0.048 | -0.4527 | No |
| 31 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 9094 | -0.049 | -0.4501 | No |
| 32 | PPAN | PPAN Entrez, Source | peter pan homolog (Drosophila) | 9124 | -0.049 | -0.4455 | No |
| 33 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 9516 | -0.056 | -0.4673 | No |
| 34 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9578 | -0.057 | -0.4640 | No |
| 35 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 9841 | -0.063 | -0.4751 | No |
| 36 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10104 | -0.068 | -0.4855 | No |
| 37 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10557 | -0.079 | -0.5087 | Yes |
| 38 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 10600 | -0.080 | -0.5009 | Yes |
| 39 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.4964 | Yes |
| 40 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 10937 | -0.089 | -0.5027 | Yes |
| 41 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11050 | -0.092 | -0.4985 | Yes |
| 42 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 11058 | -0.092 | -0.4864 | Yes |
| 43 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11229 | -0.096 | -0.4860 | Yes |
| 44 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.4758 | Yes |
| 45 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11362 | -0.101 | -0.4687 | Yes |
| 46 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11540 | -0.107 | -0.4673 | Yes |
| 47 | DUSP11 | DUSP11 Entrez, Source | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 11564 | -0.108 | -0.4542 | Yes |
| 48 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11569 | -0.108 | -0.4397 | Yes |
| 49 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 11571 | -0.108 | -0.4249 | Yes |
| 50 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.4129 | Yes |
| 51 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 11991 | -0.126 | -0.4240 | Yes |
| 52 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12128 | -0.133 | -0.4161 | Yes |
| 53 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 12190 | -0.136 | -0.4020 | Yes |
| 54 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 12198 | -0.137 | -0.3837 | Yes |
| 55 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12267 | -0.140 | -0.3696 | Yes |
| 56 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 12282 | -0.141 | -0.3513 | Yes |
| 57 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 12295 | -0.142 | -0.3327 | Yes |
| 58 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12406 | -0.149 | -0.3206 | Yes |
| 59 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12418 | -0.149 | -0.3009 | Yes |
| 60 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 12424 | -0.150 | -0.2807 | Yes |
| 61 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12437 | -0.150 | -0.2610 | Yes |
| 62 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 12438 | -0.150 | -0.2404 | Yes |
| 63 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12500 | -0.155 | -0.2237 | Yes |
| 64 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.2056 | Yes |
| 65 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 12641 | -0.167 | -0.1895 | Yes |
| 66 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.1720 | Yes |
| 67 | FBL | FBL Entrez, Source | fibrillarin | 12880 | -0.197 | -0.1561 | Yes |
| 68 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 12889 | -0.198 | -0.1296 | Yes |
| 69 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12913 | -0.201 | -0.1036 | Yes |
| 70 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12930 | -0.204 | -0.0768 | Yes |
| 71 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.0528 | Yes |
| 72 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 13101 | -0.253 | -0.0245 | Yes |
| 73 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13213 | -0.310 | 0.0097 | Yes |
