Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | RNA_SPLICING |
| Enrichment Score (ES) | -0.5329724 |
| Normalized Enrichment Score (NES) | -1.7367829 |
| Nominal p-value | 0.0042735045 |
| FDR q-value | 0.072463915 |
| FWER p-Value | 0.987 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 202 | 0.385 | 0.0765 | No |
| 2 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1181 | 0.130 | 0.0338 | No |
| 3 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 4725 | 0.020 | -0.2279 | No |
| 4 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 5699 | 0.004 | -0.3000 | No |
| 5 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 6322 | -0.005 | -0.3455 | No |
| 6 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.3528 | No |
| 7 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 7294 | -0.019 | -0.4122 | No |
| 8 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7495 | -0.022 | -0.4219 | No |
| 9 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 7658 | -0.025 | -0.4281 | No |
| 10 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7935 | -0.030 | -0.4418 | No |
| 11 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7939 | -0.030 | -0.4349 | No |
| 12 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 7988 | -0.031 | -0.4312 | No |
| 13 | SLU7 | SLU7 Entrez, Source | - | 8831 | -0.044 | -0.4840 | No |
| 14 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 9038 | -0.048 | -0.4881 | No |
| 15 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 9094 | -0.049 | -0.4806 | No |
| 16 | PPAN | PPAN Entrez, Source | peter pan homolog (Drosophila) | 9124 | -0.049 | -0.4711 | No |
| 17 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 9516 | -0.056 | -0.4871 | No |
| 18 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9578 | -0.057 | -0.4781 | No |
| 19 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 9841 | -0.063 | -0.4828 | No |
| 20 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10104 | -0.068 | -0.4862 | No |
| 21 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.5106 | Yes |
| 22 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 10937 | -0.089 | -0.5079 | Yes |
| 23 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.5097 | Yes |
| 24 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11362 | -0.101 | -0.4925 | Yes |
| 25 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11540 | -0.107 | -0.4803 | Yes |
| 26 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11569 | -0.108 | -0.4566 | Yes |
| 27 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12128 | -0.133 | -0.4669 | Yes |
| 28 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 12190 | -0.136 | -0.4391 | Yes |
| 29 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12267 | -0.140 | -0.4114 | Yes |
| 30 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12406 | -0.149 | -0.3863 | Yes |
| 31 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 12424 | -0.150 | -0.3519 | Yes |
| 32 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12437 | -0.150 | -0.3170 | Yes |
| 33 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 12438 | -0.150 | -0.2812 | Yes |
| 34 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.2518 | Yes |
| 35 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 12641 | -0.167 | -0.2188 | Yes |
| 36 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.1835 | Yes |
| 37 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 12889 | -0.198 | -0.1482 | Yes |
| 38 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12913 | -0.201 | -0.1019 | Yes |
| 39 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 13101 | -0.253 | -0.0558 | Yes |
| 40 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13213 | -0.310 | 0.0097 | Yes |
