Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetROS_MOUSE_AORTA_DN
Enrichment Score (ES)0.58577913
Normalized Enrichment Score (NES)1.9084642
Nominal p-value0.0
FDR q-value0.011637355
FWER p-Value0.57
Table: GSEA Results Summary



Fig 1: Enrichment plot: ROS_MOUSE_AORTA_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa250.7710.0844Yes
2MGPMGP
Entrez,  Source
matrix Gla protein520.6340.1533Yes
3IL1R2IL1R2
Entrez,  Source
interleukin 1 receptor, type II890.5310.2101Yes
4LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)1530.4420.2548Yes
5BGNBGN
Entrez,  Source
biglycan1750.4080.2989Yes
6GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)1990.3910.3408Yes
7CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide2290.3650.3795Yes
8FXYD5FXYD5
Entrez,  Source
FXYD domain containing ion transport regulator 52370.3550.4186Yes
9CD9CD9
Entrez,  Source
CD9 molecule2830.3200.4511Yes
10ATF3ATF3
Entrez,  Source
activating transcription factor 33100.2990.4826Yes
11S100A6S100A6
Entrez,  Source
S100 calcium binding protein A63650.2740.5092Yes
12ARG1ARG1
Entrez,  Source
arginase, liver7040.1850.5044Yes
13ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A17390.1780.5218Yes
14EMP3EMP3
Entrez,  Source
epithelial membrane protein 37550.1760.5404Yes
15ARG2ARG2
Entrez,  Source
arginase, type II7990.1700.5561Yes
16GNAI2GNAI2
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 29310.1530.5634Yes
17ANXA3ANXA3
Entrez,  Source
annexin A311700.1310.5601Yes
18IL1BIL1B
Entrez,  Source
interleukin 1, beta11970.1280.5725Yes
19GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta12100.1270.5858Yes
20ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)20580.0830.5313No
21SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)25240.0670.5038No
22PTPN23PTPN23
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 2325700.0660.5078No
23SYN1SYN1
Entrez,  Source
synapsin I26150.0650.5117No
24BTG3BTG3
Entrez,  Source
BTG family, member 326630.0630.5152No
25LCP1LCP1
Entrez,  Source
lymphocyte cytosolic protein 1 (L-plastin)28020.0600.5115No
26CTSSCTSS
Entrez,  Source
cathepsin S30840.0520.4962No
27CLUCLU
Entrez,  Source
clusterin37390.0380.4513No
28ENAHENAH
Entrez,  Source
enabled homolog (Drosophila)39070.0350.4426No
29ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)43860.0260.4095No
30CPECPE
Entrez,  Source
carboxypeptidase E44440.0250.4079No
31IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 545070.0230.4058No
32SFRP2SFRP2
Entrez,  Source
secreted frizzled-related protein 245500.0220.4052No
33PTGISPTGIS
Entrez,  Source
prostaglandin I2 (prostacyclin) synthase46530.0210.3998No
34CAPZBCAPZB
Entrez,  Source
capping protein (actin filament) muscle Z-line, beta49460.0160.3796No
35ACTBACTB
Entrez,  Source
actin, beta50410.0140.3742No
36RBP1RBP1
Entrez,  Source
retinol binding protein 1, cellular54300.0080.3459No
37DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)58150.0030.3173No
38ARL6IP2ARL6IP2
Entrez,  Source
ADP-ribosylation factor-like 6 interacting protein 26315-0.0050.2803No
39SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 16525-0.0080.2655No
40PMP22PMP22
Entrez,  Source
peripheral myelin protein 226796-0.0120.2465No
41TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)7114-0.0170.2245No
42HIF1AHIF1A
Entrez,  Source
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7751-0.0270.1797No
43CSRP1CSRP1
Entrez,  Source
cysteine and glycine-rich protein 18162-0.0330.1525No
44CD14CD14
Entrez,  Source
CD14 molecule8706-0.0420.1164No
45S100A9S100A9
Entrez,  Source
S100 calcium binding protein A99785-0.0620.0422No
46RCN2RCN2
Entrez,  Source
reticulocalbin 2, EF-hand calcium binding domain9809-0.0620.0474No
47MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle10036-0.0670.0379No
48HDCHDC
Entrez,  Source
histidine decarboxylase10195-0.0700.0339No
49BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 210960-0.089-0.0136No
50RPS5RPS5
Entrez,  Source
ribosomal protein S511396-0.102-0.0349No
51RPL18RPL18
Entrez,  Source
ribosomal protein L1811478-0.105-0.0293No
52MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)12150-0.134-0.0648No
53EXOSC7EXOSC7
Entrez,  Source
exosome component 712198-0.137-0.0530No
54PON1PON1
Entrez,  Source
paraoxonase 113268-0.372-0.0918No
55CD5LCD5L
Entrez,  Source
CD5 molecule-like13336-0.8700.0005No
Table: GSEA details [plain text format]



Fig 2: ROS_MOUSE_AORTA_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ROS_MOUSE_AORTA_DN: Random ES distribution   
Gene set null distribution of ES for ROS_MOUSE_AORTA_DN