Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | SGCGSSAAA_V$E2F1DP2_01 |
| Enrichment Score (ES) | -0.4214015 |
| Normalized Enrichment Score (NES) | -1.5415307 |
| Nominal p-value | 0.011682243 |
| FDR q-value | 0.1874185 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0306 | No |
| 2 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 321 | 0.292 | 0.0700 | No |
| 3 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 576 | 0.211 | 0.0825 | No |
| 4 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 666 | 0.194 | 0.1050 | No |
| 5 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.0749 | No |
| 6 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0694 | No |
| 7 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.0813 | No |
| 8 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 1737 | 0.096 | 0.0876 | No |
| 9 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2164 | 0.079 | 0.0673 | No |
| 10 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | 0.0556 | No |
| 11 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 2911 | 0.057 | 0.0301 | No |
| 12 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0520 | No |
| 13 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | -0.0596 | No |
| 14 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.0700 | No |
| 15 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.1043 | No |
| 16 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4937 | 0.016 | -0.1043 | No |
| 17 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.1246 | No |
| 18 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1569 | No |
| 19 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 5683 | 0.005 | -0.1572 | No |
| 20 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 5699 | 0.004 | -0.1577 | No |
| 21 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.1608 | No |
| 22 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1616 | No |
| 23 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1793 | No |
| 24 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.1991 | No |
| 25 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.2106 | No |
| 26 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.2207 | No |
| 27 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.2257 | No |
| 28 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.2390 | No |
| 29 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 7823 | -0.028 | -0.3053 | No |
| 30 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7843 | -0.028 | -0.3026 | No |
| 31 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.3140 | No |
| 32 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.3375 | No |
| 33 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3406 | No |
| 34 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.3891 | No |
| 35 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 9616 | -0.058 | -0.4026 | No |
| 36 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 9690 | -0.060 | -0.3991 | No |
| 37 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.3924 | No |
| 38 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.3985 | No |
| 39 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.3898 | No |
| 40 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.4090 | No |
| 41 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.4096 | Yes |
| 42 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.3999 | Yes |
| 43 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.4012 | Yes |
| 44 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 10807 | -0.085 | -0.3940 | Yes |
| 45 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 10963 | -0.089 | -0.3922 | Yes |
| 46 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.3858 | Yes |
| 47 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3768 | Yes |
| 48 | RET | RET Entrez, Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 11258 | -0.097 | -0.3716 | Yes |
| 49 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.3580 | Yes |
| 50 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 11511 | -0.106 | -0.3600 | Yes |
| 51 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3511 | Yes |
| 52 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.3451 | Yes |
| 53 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3323 | Yes |
| 54 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12203 | -0.137 | -0.3396 | Yes |
| 55 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.3380 | Yes |
| 56 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12533 | -0.157 | -0.3176 | Yes |
| 57 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.2950 | Yes |
| 58 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.2746 | Yes |
| 59 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.2560 | Yes |
| 60 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.2313 | Yes |
| 61 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.2066 | Yes |
| 62 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.1880 | Yes |
| 63 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.1621 | Yes |
| 64 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1290 | Yes |
| 65 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.0958 | Yes |
| 66 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.0620 | Yes |
| 67 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.0288 | Yes |
| 68 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | 0.0104 | Yes |
