Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | SHEPARD_BMYB_MORPHOLINO_UP |
| Enrichment Score (ES) | 0.5022671 |
| Normalized Enrichment Score (NES) | 1.8283815 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021785988 |
| FWER p-Value | 0.904 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 9 | 0.936 | 0.0868 | Yes |
| 2 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 28 | 0.756 | 0.1561 | Yes |
| 3 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 35 | 0.711 | 0.2221 | Yes |
| 4 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 164 | 0.430 | 0.2526 | Yes |
| 5 | FST | FST Entrez, Source | follistatin | 169 | 0.423 | 0.2918 | Yes |
| 6 | BGN | BGN Entrez, Source | biglycan | 175 | 0.408 | 0.3296 | Yes |
| 7 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 302 | 0.308 | 0.3489 | Yes |
| 8 | DNAJB4 | DNAJB4 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 4 | 410 | 0.256 | 0.3647 | Yes |
| 9 | HSBP1 | HSBP1 Entrez, Source | heat shock factor binding protein 1 | 416 | 0.254 | 0.3881 | Yes |
| 10 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 580 | 0.210 | 0.3954 | Yes |
| 11 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 620 | 0.203 | 0.4114 | Yes |
| 12 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 682 | 0.188 | 0.4244 | Yes |
| 13 | FBXO32 | FBXO32 Entrez, Source | F-box protein 32 | 694 | 0.186 | 0.4410 | Yes |
| 14 | ARG1 | ARG1 Entrez, Source | arginase, liver | 704 | 0.185 | 0.4576 | Yes |
| 15 | RASL11B | RASL11B Entrez, Source | RAS-like, family 11, member B | 800 | 0.170 | 0.4663 | Yes |
| 16 | RAB3C | RAB3C Entrez, Source | RAB3C, member RAS oncogene family | 830 | 0.165 | 0.4795 | Yes |
| 17 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 855 | 0.162 | 0.4928 | Yes |
| 18 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 921 | 0.154 | 0.5023 | Yes |
| 19 | SH3GLB2 | SH3GLB2 Entrez, Source | SH3-domain GRB2-like endophilin B2 | 1376 | 0.115 | 0.4787 | No |
| 20 | GMPR | GMPR Entrez, Source | guanosine monophosphate reductase | 1649 | 0.100 | 0.4676 | No |
| 21 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 1744 | 0.095 | 0.4694 | No |
| 22 | GNS | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) | 1850 | 0.091 | 0.4699 | No |
| 23 | UPB1 | UPB1 Entrez, Source | ureidopropionase, beta | 1899 | 0.089 | 0.4746 | No |
| 24 | ATP6V1C2 | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 1943 | 0.087 | 0.4795 | No |
| 25 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1962 | 0.087 | 0.4862 | No |
| 26 | HFE | HFE Entrez, Source | hemochromatosis | 2035 | 0.084 | 0.4886 | No |
| 27 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2036 | 0.084 | 0.4964 | No |
| 28 | AK3 | AK3 Entrez, Source | adenylate kinase 3 | 2456 | 0.069 | 0.4713 | No |
| 29 | GNAI3 | GNAI3 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 3147 | 0.051 | 0.4239 | No |
| 30 | CYP26B1 | CYP26B1 Entrez, Source | cytochrome P450, family 26, subfamily B, polypeptide 1 | 3231 | 0.049 | 0.4222 | No |
| 31 | DLGAP4 | DLGAP4 Entrez, Source | discs, large (Drosophila) homolog-associated protein 4 | 3449 | 0.044 | 0.4100 | No |
| 32 | WNT11 | WNT11 Entrez, Source | wingless-type MMTV integration site family, member 11 | 3495 | 0.043 | 0.4106 | No |
| 33 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 3949 | 0.034 | 0.3796 | No |
| 34 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 4072 | 0.031 | 0.3733 | No |
| 35 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 4301 | 0.027 | 0.3586 | No |
| 36 | SYBL1 | SYBL1 Entrez, Source | synaptobrevin-like 1 | 4597 | 0.022 | 0.3384 | No |
| 37 | FNTB | FNTB Entrez, Source | farnesyltransferase, CAAX box, beta | 4744 | 0.019 | 0.3292 | No |
| 38 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 4877 | 0.017 | 0.3208 | No |
| 39 | PTP4A2 | PTP4A2 Entrez, Source | protein tyrosine phosphatase type IVA, member 2 | 5024 | 0.015 | 0.3112 | No |
| 40 | PDC | PDC Entrez, Source | phosducin | 5082 | 0.014 | 0.3082 | No |
| 41 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 5093 | 0.014 | 0.3087 | No |
| 42 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 5583 | 0.006 | 0.2723 | No |
| 43 | PNPO | PNPO Entrez, Source | pyridoxamine 5'-phosphate oxidase | 5606 | 0.006 | 0.2712 | No |
| 44 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 5728 | 0.004 | 0.2624 | No |
| 45 | CAMK1G | CAMK1G Entrez, Source | calcium/calmodulin-dependent protein kinase IG | 5773 | 0.003 | 0.2594 | No |
| 46 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 5780 | 0.003 | 0.2592 | No |
| 47 | B2M | B2M Entrez, Source | beta-2-microglobulin | 5795 | 0.003 | 0.2584 | No |
| 48 | RDH10 | RDH10 Entrez, Source | retinol dehydrogenase 10 (all-trans) | 5982 | 0.000 | 0.2444 | No |
| 49 | NAPE-PLD | NAPE-PLD Entrez, Source | - | 6144 | -0.002 | 0.2325 | No |
| 50 | SQSTM1 | SQSTM1 Entrez, Source | sequestosome 1 | 6184 | -0.003 | 0.2298 | No |
| 51 | GPC4 | GPC4 Entrez, Source | glypican 4 | 6215 | -0.003 | 0.2278 | No |
| 52 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 6406 | -0.006 | 0.2141 | No |
| 53 | EFHD2 | EFHD2 Entrez, Source | EF-hand domain family, member D2 | 6720 | -0.011 | 0.1915 | No |
| 54 | VDAC3 | VDAC3 Entrez, Source | voltage-dependent anion channel 3 | 6808 | -0.012 | 0.1861 | No |
| 55 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 6879 | -0.013 | 0.1820 | No |
| 56 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6949 | -0.014 | 0.1782 | No |
| 57 | CUBN | CUBN Entrez, Source | cubilin (intrinsic factor-cobalamin receptor) | 7059 | -0.016 | 0.1714 | No |
| 58 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 7326 | -0.020 | 0.1532 | No |
| 59 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 7799 | -0.027 | 0.1202 | No |
| 60 | PSMD3 | PSMD3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 7835 | -0.028 | 0.1201 | No |
| 61 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 8067 | -0.032 | 0.1057 | No |
| 62 | DNAJA2 | DNAJA2 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 2 | 8107 | -0.032 | 0.1058 | No |
| 63 | PAPOLB | PAPOLB Entrez, Source | poly(A) polymerase beta (testis specific) | 8516 | -0.039 | 0.0786 | No |
| 64 | MBP | MBP Entrez, Source | myelin basic protein | 8983 | -0.047 | 0.0478 | No |
| 65 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | 0.0371 | No |
| 66 | TPD52L2 | TPD52L2 Entrez, Source | tumor protein D52-like 2 | 9634 | -0.058 | 0.0090 | No |
| 67 | PTPRN | PTPRN Entrez, Source | protein tyrosine phosphatase, receptor type, N | 9636 | -0.058 | 0.0144 | No |
| 68 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 9903 | -0.064 | 0.0003 | No |
| 69 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | 0.0030 | No |
| 70 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 10057 | -0.068 | 0.0013 | No |
| 71 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 10293 | -0.072 | -0.0097 | No |
| 72 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10615 | -0.080 | -0.0264 | No |
| 73 | SND1 | SND1 Entrez, Source | - | 10707 | -0.083 | -0.0255 | No |
| 74 | CPN1 | CPN1 Entrez, Source | carboxypeptidase N, polypeptide 1, 50kD | 10726 | -0.083 | -0.0191 | No |
| 75 | SLC31A1 | SLC31A1 Entrez, Source | solute carrier family 31 (copper transporters), member 1 | 11210 | -0.096 | -0.0466 | No |
| 76 | NUDT9 | NUDT9 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 11295 | -0.098 | -0.0437 | No |
| 77 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11337 | -0.100 | -0.0375 | No |
| 78 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11346 | -0.100 | -0.0287 | No |
| 79 | OSGEPL1 | OSGEPL1 Entrez, Source | O-sialoglycoprotein endopeptidase-like 1 | 11356 | -0.100 | -0.0200 | No |
| 80 | WHSC2 | WHSC2 Entrez, Source | Wolf-Hirschhorn syndrome candidate 2 | 11360 | -0.101 | -0.0109 | No |
| 81 | MRPS18B | MRPS18B Entrez, Source | mitochondrial ribosomal protein S18B | 11420 | -0.103 | -0.0057 | No |
| 82 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.0099 | No |
| 83 | STIP1 | STIP1 Entrez, Source | stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) | 11703 | -0.113 | -0.0061 | No |
| 84 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 11748 | -0.115 | 0.0013 | No |
| 85 | SNX27 | SNX27 Entrez, Source | sorting nexin family member 27 | 11872 | -0.120 | 0.0033 | No |
| 86 | DNAJA3 | DNAJA3 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 3 | 11979 | -0.125 | 0.0070 | No |
| 87 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 11991 | -0.126 | 0.0180 | No |
| 88 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 12073 | -0.130 | 0.0240 | No |
| 89 | PLAA | PLAA Entrez, Source | phospholipase A2-activating protein | 12215 | -0.137 | 0.0262 | No |
| 90 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 12338 | -0.145 | 0.0305 | No |
| 91 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12354 | -0.146 | 0.0430 | No |
| 92 | KNS2 | KNS2 Entrez, Source | kinesin 2 | 12584 | -0.161 | 0.0408 | No |
| 93 | MINA | MINA Entrez, Source | MYC induced nuclear antigen | 12713 | -0.175 | 0.0475 | No |
