Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | STATIN_PATHWAY_PHARMGKB |
| Enrichment Score (ES) | 0.71992964 |
| Normalized Enrichment Score (NES) | 1.8185327 |
| Nominal p-value | 0.007920792 |
| FDR q-value | 0.022998229 |
| FWER p-Value | 0.932 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LPL | LPL Entrez, Source | lipoprotein lipase | 45 | 0.671 | 0.1921 | Yes |
| 2 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 85 | 0.548 | 0.3490 | Yes |
| 3 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 151 | 0.445 | 0.4738 | Yes |
| 4 | LIPC | LIPC Entrez, Source | lipase, hepatic | 193 | 0.397 | 0.5863 | Yes |
| 5 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 253 | 0.340 | 0.6808 | Yes |
| 6 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 620 | 0.203 | 0.7124 | Yes |
| 7 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 1096 | 0.137 | 0.7166 | Yes |
| 8 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1529 | 0.106 | 0.7151 | Yes |
| 9 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 1886 | 0.089 | 0.7143 | Yes |
| 10 | APOE | APOE Entrez, Source | apolipoprotein E | 2123 | 0.080 | 0.7199 | Yes |
| 11 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 3172 | 0.050 | 0.6559 | No |
| 12 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 5574 | 0.006 | 0.4776 | No |
| 13 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 5770 | 0.003 | 0.4638 | No |
| 14 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 8062 | -0.032 | 0.3012 | No |
| 15 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 11627 | -0.110 | 0.0659 | No |
| 16 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 12984 | -0.215 | 0.0269 | No |
