Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | STRUCTURE_SPECIFIC_DNA_BINDING |
| Enrichment Score (ES) | -0.508925 |
| Normalized Enrichment Score (NES) | -1.5644045 |
| Nominal p-value | 0.016241299 |
| FDR q-value | 0.16331032 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 832 | 0.165 | -0.0045 | No |
| 2 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 2276 | 0.075 | -0.0867 | No |
| 3 | RAD23A | RAD23A Entrez, Source | RAD23 homolog A (S. cerevisiae) | 2288 | 0.074 | -0.0613 | No |
| 4 | FOXC2 | FOXC2 Entrez, Source | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 4080 | 0.031 | -0.1848 | No |
| 5 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 4322 | 0.027 | -0.1935 | No |
| 6 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.1915 | No |
| 7 | HLF | HLF Entrez, Source | hepatic leukemia factor | 4632 | 0.021 | -0.2003 | No |
| 8 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 5310 | 0.010 | -0.2476 | No |
| 9 | IGHMBP2 | IGHMBP2 Entrez, Source | immunoglobulin mu binding protein 2 | 7514 | -0.023 | -0.4052 | No |
| 10 | SUB1 | SUB1 Entrez, Source | SUB1 homolog (S. cerevisiae) | 7882 | -0.029 | -0.4226 | No |
| 11 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 8430 | -0.038 | -0.4504 | No |
| 12 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 8663 | -0.041 | -0.4533 | No |
| 13 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 9405 | -0.054 | -0.4899 | Yes |
| 14 | WBP11 | WBP11 Entrez, Source | WW domain binding protein 11 | 9454 | -0.055 | -0.4740 | Yes |
| 15 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 9740 | -0.061 | -0.4741 | Yes |
| 16 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 9780 | -0.062 | -0.4554 | Yes |
| 17 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 10457 | -0.077 | -0.4792 | Yes |
| 18 | PNKP | PNKP Entrez, Source | polynucleotide kinase 3'-phosphatase | 10519 | -0.078 | -0.4563 | Yes |
| 19 | MTERF | MTERF Entrez, Source | mitochondrial transcription termination factor | 10596 | -0.080 | -0.4339 | Yes |
| 20 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 10679 | -0.082 | -0.4113 | Yes |
| 21 | TREX1 | TREX1 Entrez, Source | three prime repair exonuclease 1 | 11036 | -0.091 | -0.4059 | Yes |
| 22 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11337 | -0.100 | -0.3933 | Yes |
| 23 | SAFB | SAFB Entrez, Source | scaffold attachment factor B | 11983 | -0.126 | -0.3976 | Yes |
| 24 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 12392 | -0.148 | -0.3762 | Yes |
| 25 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 12812 | -0.187 | -0.3419 | Yes |
| 26 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 13004 | -0.219 | -0.2792 | Yes |
| 27 | APTX | APTX Entrez, Source | aprataxin | 13079 | -0.242 | -0.1995 | Yes |
| 28 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 13175 | -0.284 | -0.1067 | Yes |
| 29 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13244 | -0.339 | 0.0074 | Yes |
