Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TAKEDA_NUP8_HOXA9_10D_DN |
| Enrichment Score (ES) | 0.63603723 |
| Normalized Enrichment Score (NES) | 2.2287707 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.4103854E-4 |
| FWER p-Value | 0.0020 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 18 | 0.797 | 0.0633 | Yes |
| 2 | CD24 | CD24 Entrez, Source | CD24 molecule | 26 | 0.771 | 0.1253 | Yes |
| 3 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 43 | 0.675 | 0.1788 | Yes |
| 4 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 84 | 0.549 | 0.2203 | Yes |
| 5 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 89 | 0.531 | 0.2631 | Yes |
| 6 | RNASE1 | RNASE1 Entrez, Source | ribonuclease, RNase A family, 1 (pancreatic) | 94 | 0.529 | 0.3057 | Yes |
| 7 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 101 | 0.510 | 0.3466 | Yes |
| 8 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 138 | 0.458 | 0.3811 | Yes |
| 9 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 163 | 0.430 | 0.4141 | Yes |
| 10 | RASSF4 | RASSF4 Entrez, Source | Ras association (RalGDS/AF-6) domain family 4 | 186 | 0.402 | 0.4451 | Yes |
| 11 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 200 | 0.388 | 0.4755 | Yes |
| 12 | HS3ST2 | HS3ST2 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 219 | 0.370 | 0.5042 | Yes |
| 13 | ST14 | ST14 Entrez, Source | suppression of tumorigenicity 14 (colon carcinoma) | 232 | 0.362 | 0.5327 | Yes |
| 14 | CD9 | CD9 Entrez, Source | CD9 molecule | 283 | 0.320 | 0.5549 | Yes |
| 15 | TSPAN2 | TSPAN2 Entrez, Source | tetraspanin 2 | 311 | 0.298 | 0.5770 | Yes |
| 16 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 533 | 0.219 | 0.5781 | Yes |
| 17 | C1QC | C1QC Entrez, Source | complement component 1, q subcomponent, C chain | 550 | 0.217 | 0.5945 | Yes |
| 18 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 860 | 0.161 | 0.5843 | Yes |
| 19 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 984 | 0.148 | 0.5870 | Yes |
| 20 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1007 | 0.146 | 0.5972 | Yes |
| 21 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 1041 | 0.142 | 0.6063 | Yes |
| 22 | PDE4DIP | PDE4DIP Entrez, Source | phosphodiesterase 4D interacting protein (myomegalin) | 1077 | 0.138 | 0.6148 | Yes |
| 23 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 1114 | 0.135 | 0.6231 | Yes |
| 24 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 1170 | 0.131 | 0.6295 | Yes |
| 25 | C1QA | C1QA Entrez, Source | complement component 1, q subcomponent, A chain | 1220 | 0.126 | 0.6360 | Yes |
| 26 | TMEM45B | TMEM45B Entrez, Source | transmembrane protein 45B | 1449 | 0.111 | 0.6278 | No |
| 27 | MS4A2 | MS4A2 Entrez, Source | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 1571 | 0.104 | 0.6271 | No |
| 28 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 1678 | 0.098 | 0.6271 | No |
| 29 | LGMN | LGMN Entrez, Source | legumain | 1864 | 0.090 | 0.6205 | No |
| 30 | APOE | APOE Entrez, Source | apolipoprotein E | 2123 | 0.080 | 0.6075 | No |
| 31 | HS3ST1 | HS3ST1 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 2172 | 0.078 | 0.6102 | No |
| 32 | FCER1A | FCER1A Entrez, Source | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 2214 | 0.077 | 0.6133 | No |
| 33 | ACSL6 | ACSL6 Entrez, Source | acyl-CoA synthetase long-chain family member 6 | 2697 | 0.063 | 0.5821 | No |
| 34 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 2700 | 0.063 | 0.5870 | No |
| 35 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 2902 | 0.057 | 0.5765 | No |
| 36 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 3017 | 0.054 | 0.5723 | No |
| 37 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3285 | 0.048 | 0.5560 | No |
| 38 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 3540 | 0.042 | 0.5402 | No |
| 39 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 3625 | 0.040 | 0.5372 | No |
| 40 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 3898 | 0.035 | 0.5195 | No |
| 41 | HRH4 | HRH4 Entrez, Source | histamine receptor H4 | 3986 | 0.033 | 0.5156 | No |
| 42 | ACP5 | ACP5 Entrez, Source | acid phosphatase 5, tartrate resistant | 4056 | 0.032 | 0.5130 | No |
| 43 | RGC32 | RGC32 Entrez, Source | - | 4104 | 0.031 | 0.5119 | No |
| 44 | RPS6KA2 | RPS6KA2 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 4460 | 0.024 | 0.4871 | No |
| 45 | PPP1R1B | PPP1R1B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) | 4556 | 0.022 | 0.4818 | No |
| 46 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 4697 | 0.020 | 0.4728 | No |
| 47 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 4730 | 0.020 | 0.4720 | No |
| 48 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 5439 | 0.008 | 0.4193 | No |
| 49 | KCNJ15 | KCNJ15 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 15 | 5526 | 0.007 | 0.4134 | No |
| 50 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 5599 | 0.006 | 0.4084 | No |
| 51 | C5AR1 | C5AR1 Entrez, Source | complement component 5a receptor 1 | 5691 | 0.004 | 0.4019 | No |
| 52 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 5751 | 0.003 | 0.3977 | No |
| 53 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 6353 | -0.006 | 0.3528 | No |
| 54 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 6591 | -0.009 | 0.3357 | No |
| 55 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | 0.3297 | No |
| 56 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 6833 | -0.013 | 0.3195 | No |
| 57 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 7051 | -0.016 | 0.3044 | No |
| 58 | ACE | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 7112 | -0.017 | 0.3012 | No |
| 59 | CORO2A | CORO2A Entrez, Source | coronin, actin binding protein, 2A | 7122 | -0.017 | 0.3019 | No |
| 60 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 7240 | -0.019 | 0.2946 | No |
| 61 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 7274 | -0.019 | 0.2937 | No |
| 62 | OLIG1 | OLIG1 Entrez, Source | oligodendrocyte transcription factor 1 | 7444 | -0.022 | 0.2827 | No |
| 63 | SLC7A8 | SLC7A8 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 7714 | -0.026 | 0.2645 | No |
| 64 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 7770 | -0.027 | 0.2626 | No |
| 65 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 8724 | -0.043 | 0.1942 | No |
| 66 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 8923 | -0.046 | 0.1830 | No |
| 67 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 9192 | -0.050 | 0.1668 | No |
| 68 | SLC25A27 | SLC25A27 Entrez, Source | solute carrier family 25, member 27 | 9626 | -0.058 | 0.1389 | No |
| 69 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 10000 | -0.066 | 0.1162 | No |
| 70 | CEBPE | CEBPE Entrez, Source | CCAAT/enhancer binding protein (C/EBP), epsilon | 10021 | -0.067 | 0.1201 | No |
| 71 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 10196 | -0.070 | 0.1127 | No |
| 72 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 10360 | -0.074 | 0.1064 | No |
| 73 | BLNK | BLNK Entrez, Source | B-cell linker | 10728 | -0.083 | 0.0854 | No |
| 74 | CTSB | CTSB Entrez, Source | cathepsin B | 10843 | -0.086 | 0.0839 | No |
| 75 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 11070 | -0.092 | 0.0743 | No |
| 76 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 11118 | -0.094 | 0.0784 | No |
| 77 | PCSK5 | PCSK5 Entrez, Source | proprotein convertase subtilisin/kexin type 5 | 11725 | -0.114 | 0.0419 | No |
| 78 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 11850 | -0.119 | 0.0422 | No |
| 79 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 12069 | -0.130 | 0.0363 | No |
| 80 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12150 | -0.134 | 0.0412 | No |
| 81 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 12485 | -0.154 | 0.0285 | No |
| 82 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 12923 | -0.203 | 0.0120 | No |
| 83 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 13073 | -0.241 | 0.0203 | No |
