Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TGFBETA_EARLY_UP |
| Enrichment Score (ES) | 0.67620975 |
| Normalized Enrichment Score (NES) | 2.0369277 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.002840976 |
| FWER p-Value | 0.11 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 6 | 1.154 | 0.1791 | Yes |
| 2 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 21 | 0.785 | 0.3002 | Yes |
| 3 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 56 | 0.628 | 0.3953 | Yes |
| 4 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 166 | 0.428 | 0.4537 | Yes |
| 5 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 230 | 0.365 | 0.5057 | Yes |
| 6 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 317 | 0.293 | 0.5449 | Yes |
| 7 | PXN | PXN Entrez, Source | paxillin | 425 | 0.252 | 0.5760 | Yes |
| 8 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 533 | 0.219 | 0.6021 | Yes |
| 9 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 571 | 0.212 | 0.6323 | Yes |
| 10 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 709 | 0.184 | 0.6506 | Yes |
| 11 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 759 | 0.176 | 0.6743 | Yes |
| 12 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 1034 | 0.144 | 0.6761 | Yes |
| 13 | WNT2B | WNT2B Entrez, Source | wingless-type MMTV integration site family, member 2B | 1284 | 0.121 | 0.6762 | Yes |
| 14 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 1566 | 0.104 | 0.6713 | No |
| 15 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 1859 | 0.090 | 0.6634 | No |
| 16 | ZYX | ZYX Entrez, Source | zyxin | 2654 | 0.063 | 0.6136 | No |
| 17 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2715 | 0.062 | 0.6188 | No |
| 18 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 2772 | 0.061 | 0.6241 | No |
| 19 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 3937 | 0.034 | 0.5419 | No |
| 20 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4507 | 0.023 | 0.5027 | No |
| 21 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 4808 | 0.018 | 0.4830 | No |
| 22 | NID1 | NID1 Entrez, Source | nidogen 1 | 5553 | 0.007 | 0.4281 | No |
| 23 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 5611 | 0.005 | 0.4247 | No |
| 24 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 5770 | 0.003 | 0.4133 | No |
| 25 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 6129 | -0.002 | 0.3867 | No |
| 26 | JUP | JUP Entrez, Source | junction plakoglobin | 6593 | -0.009 | 0.3533 | No |
| 27 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 7208 | -0.018 | 0.3100 | No |
| 28 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 7625 | -0.025 | 0.2826 | No |
| 29 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 8238 | -0.035 | 0.2419 | No |
| 30 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 9690 | -0.060 | 0.1421 | No |
| 31 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 9946 | -0.065 | 0.1331 | No |
| 32 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 10103 | -0.068 | 0.1321 | No |
| 33 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 10432 | -0.076 | 0.1192 | No |
| 34 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 10450 | -0.076 | 0.1298 | No |
| 35 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 10770 | -0.085 | 0.1190 | No |
| 36 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 11646 | -0.111 | 0.0705 | No |
| 37 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 12769 | -0.180 | 0.0141 | No |
| 38 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12802 | -0.185 | 0.0406 | No |
