Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TPA_SENS_MIDDLE_UP |
| Enrichment Score (ES) | 0.6939478 |
| Normalized Enrichment Score (NES) | 2.164753 |
| Nominal p-value | 0.0 |
| FDR q-value | 5.84144E-4 |
| FWER p-Value | 0.0080 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 4 | 1.225 | 0.1624 | Yes |
| 2 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 56 | 0.628 | 0.2419 | Yes |
| 3 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 87 | 0.537 | 0.3110 | Yes |
| 4 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 145 | 0.452 | 0.3667 | Yes |
| 5 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 160 | 0.434 | 0.4233 | Yes |
| 6 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 229 | 0.365 | 0.4666 | Yes |
| 7 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 353 | 0.281 | 0.4946 | Yes |
| 8 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 485 | 0.232 | 0.5155 | Yes |
| 9 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 616 | 0.203 | 0.5327 | Yes |
| 10 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 659 | 0.195 | 0.5555 | Yes |
| 11 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 735 | 0.179 | 0.5737 | Yes |
| 12 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 754 | 0.176 | 0.5957 | Yes |
| 13 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 755 | 0.176 | 0.6191 | Yes |
| 14 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 784 | 0.172 | 0.6399 | Yes |
| 15 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 834 | 0.165 | 0.6581 | Yes |
| 16 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 860 | 0.161 | 0.6776 | Yes |
| 17 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 959 | 0.151 | 0.6902 | Yes |
| 18 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1191 | 0.129 | 0.6900 | Yes |
| 19 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 1504 | 0.108 | 0.6808 | Yes |
| 20 | AQP4 | AQP4 Entrez, Source | aquaporin 4 | 1520 | 0.107 | 0.6939 | Yes |
| 21 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 1849 | 0.091 | 0.6813 | No |
| 22 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 2582 | 0.065 | 0.6349 | No |
| 23 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 2724 | 0.062 | 0.6325 | No |
| 24 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 2746 | 0.061 | 0.6391 | No |
| 25 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 2983 | 0.055 | 0.6287 | No |
| 26 | AGA | AGA Entrez, Source | aspartylglucosaminidase | 3695 | 0.039 | 0.5803 | No |
| 27 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 4084 | 0.031 | 0.5553 | No |
| 28 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 5059 | 0.014 | 0.4839 | No |
| 29 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 5081 | 0.014 | 0.4842 | No |
| 30 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 5146 | 0.012 | 0.4810 | No |
| 31 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 5579 | 0.006 | 0.4493 | No |
| 32 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 5673 | 0.005 | 0.4430 | No |
| 33 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 6554 | -0.008 | 0.3779 | No |
| 34 | HSPA8 | HSPA8 Entrez, Source | heat shock 70kDa protein 8 | 6613 | -0.009 | 0.3747 | No |
| 35 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 7555 | -0.023 | 0.3071 | No |
| 36 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 7559 | -0.024 | 0.3100 | No |
| 37 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 7790 | -0.027 | 0.2963 | No |
| 38 | PREP | PREP Entrez, Source | prolyl endopeptidase | 8025 | -0.031 | 0.2829 | No |
| 39 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 8391 | -0.037 | 0.2603 | No |
| 40 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 8984 | -0.047 | 0.2221 | No |
| 41 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 10398 | -0.075 | 0.1257 | No |
| 42 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 10937 | -0.089 | 0.0971 | No |
| 43 | PIK3CB | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 11031 | -0.091 | 0.1022 | No |
| 44 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 11438 | -0.104 | 0.0854 | No |
| 45 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 11472 | -0.105 | 0.0969 | No |
| 46 | SLC13A3 | SLC13A3 Entrez, Source | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 12462 | -0.152 | 0.0426 | No |
| 47 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12736 | -0.177 | 0.0456 | No |
