Details for gene set UVB_NHEK1

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	UVB_NHEK1_UP
Enrichment Score (ES)	0.5082857
Normalized Enrichment Score (NES)	1.8598871
Nominal p-value	0.0
FDR q-value	0.017989326
FWER p-Value	0.806

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CTGF	CTGF Entrez, Source	connective tissue growth factor	27	0.757	0.0604	Yes
2	IL1RL1	IL1RL1 Entrez, Source	interleukin 1 receptor-like 1	31	0.742	0.1213	Yes
3	CCL20	CCL20 Entrez, Source	chemokine (C-C motif) ligand 20	50	0.641	0.1728	Yes
4	HMGCS2	HMGCS2 Entrez, Source	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	83	0.552	0.2159	Yes
5	ADM	ADM Entrez, Source	adrenomedullin	96	0.523	0.2581	Yes
6	CXCL2	CXCL2 Entrez, Source	chemokine (C-X-C motif) ligand 2	138	0.458	0.2928	Yes
7	SGK	SGK Entrez, Source	serum/glucocorticoid regulated kinase	200	0.388	0.3202	Yes
8	CYBA	CYBA Entrez, Source	cytochrome b-245, alpha polypeptide	229	0.365	0.3482	Yes
9	CITED2	CITED2 Entrez, Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	297	0.311	0.3687	Yes
10	ATF3	ATF3 Entrez, Source	activating transcription factor 3	310	0.299	0.3925	Yes
11	IER3	IER3 Entrez, Source	immediate early response 3	392	0.264	0.4082	Yes
12	CLDN4	CLDN4 Entrez, Source	claudin 4	570	0.212	0.4123	Yes
13	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	585	0.209	0.4284	Yes
14	CYR61	CYR61 Entrez, Source	cysteine-rich, angiogenic inducer, 61	600	0.206	0.4444	Yes
15	ITPR1	ITPR1 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 1	816	0.167	0.4419	Yes
16	TGFB1	TGFB1 Entrez, Source	transforming growth factor, beta 1 (Camurati-Engelmann disease)	821	0.166	0.4553	Yes
17	NEU1	NEU1 Entrez, Source	sialidase 1 (lysosomal sialidase)	827	0.166	0.4686	Yes
18	NR1D1	NR1D1 Entrez, Source	nuclear receptor subfamily 1, group D, member 1	920	0.154	0.4744	Yes
19	KYNU	KYNU Entrez, Source	kynureninase (L-kynurenine hydrolase)	934	0.153	0.4860	Yes
20	CHRNB1	CHRNB1 Entrez, Source	cholinergic receptor, nicotinic, beta 1 (muscle)	1167	0.131	0.4793	Yes
21	GADD45B	GADD45B Entrez, Source	growth arrest and DNA-damage-inducible, beta	1210	0.127	0.4866	Yes
22	PHLDA1	PHLDA1 Entrez, Source	pleckstrin homology-like domain, family A, member 1	1221	0.126	0.4962	Yes
23	DUSP1	DUSP1 Entrez, Source	dual specificity phosphatase 1	1261	0.123	0.5034	Yes
24	IER2	IER2 Entrez, Source	immediate early response 2	1461	0.110	0.4974	Yes
25	GUK1	GUK1 Entrez, Source	guanylate kinase 1	1609	0.102	0.4947	Yes
26	CST6	CST6 Entrez, Source	cystatin E/M	1669	0.099	0.4984	Yes
27	ACO2	ACO2 Entrez, Source	aconitase 2, mitochondrial	1737	0.096	0.5013	Yes
28	COL11A1	COL11A1 Entrez, Source	collagen, type XI, alpha 1	1749	0.095	0.5083	Yes
29	HBEGF	HBEGF Entrez, Source	heparin-binding EGF-like growth factor	1849	0.091	0.5083	No
30	APOE	APOE Entrez, Source	apolipoprotein E	2123	0.080	0.4942	No
31	CLTB	CLTB Entrez, Source	clathrin, light chain (Lcb)	2253	0.076	0.4907	No
32	IGFBP6	IGFBP6 Entrez, Source	insulin-like growth factor binding protein 6	2356	0.072	0.4890	No
33	MYF6	MYF6 Entrez, Source	myogenic factor 6 (herculin)	2600	0.065	0.4760	No
34	BTG1	BTG1 Entrez, Source	B-cell translocation gene 1, anti-proliferative	2629	0.064	0.4791	No
35	UQCRB	UQCRB Entrez, Source	ubiquinol-cytochrome c reductase binding protein	2719	0.062	0.4775	No
36	TRIB1	TRIB1 Entrez, Source	tribbles homolog 1 (Drosophila)	2792	0.060	0.4771	No
37	MAP1LC3B	MAP1LC3B Entrez, Source	microtubule-associated protein 1 light chain 3 beta	2854	0.059	0.4773	No
38	PCTK1	PCTK1 Entrez, Source	PCTAIRE protein kinase 1	3282	0.048	0.4490	No
39	GPI	GPI Entrez, Source	glucose phosphate isomerase	3287	0.048	0.4526	No
40	CCNA1	CCNA1 Entrez, Source	cyclin A1	3333	0.046	0.4530	No
41	CEACAM1	CEACAM1 Entrez, Source	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	3419	0.045	0.4503	No
42	COX7A2	COX7A2 Entrez, Source	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	3787	0.037	0.4256	No
43	PSMD8	PSMD8 Entrez, Source	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	3796	0.037	0.4280	No
44	YKT6	YKT6 Entrez, Source	YKT6 v-SNARE homolog (S. cerevisiae)	3808	0.036	0.4302	No
45	JUND	JUND Entrez, Source	jun D proto-oncogene	3846	0.036	0.4303	No
46	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	3854	0.036	0.4327	No
47	BAMBI	BAMBI Entrez, Source	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	3945	0.034	0.4287	No
48	ANXA2	ANXA2 Entrez, Source	annexin A2	3949	0.034	0.4313	No
49	PPIF	PPIF Entrez, Source	peptidylprolyl isomerase F (cyclophilin F)	4337	0.027	0.4042	No
50	CAPNS1	CAPNS1 Entrez, Source	calpain, small subunit 1	4360	0.026	0.4047	No
51	STXBP2	STXBP2 Entrez, Source	syntaxin binding protein 2	4719	0.020	0.3793	No
52	TAGLN3	TAGLN3 Entrez, Source	transgelin 3	4815	0.018	0.3736	No
53	SPINK1	SPINK1 Entrez, Source	serine peptidase inhibitor, Kazal type 1	4848	0.018	0.3727	No
54	HCRT	HCRT Entrez, Source	hypocretin (orexin) neuropeptide precursor	5181	0.012	0.3486	No
55	CHRNB4	CHRNB4 Entrez, Source	cholinergic receptor, nicotinic, beta 4	5454	0.008	0.3287	No
56	MNAT1	MNAT1 Entrez, Source	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	5616	0.005	0.3170	No
57	DYNLL1	DYNLL1 Entrez, Source	dynein, light chain, LC8-type 1	5673	0.005	0.3131	No
58	BCL2	BCL2 Entrez, Source	B-cell CLL/lymphoma 2	6363	-0.006	0.2615	No
59	BRD2	BRD2 Entrez, Source	bromodomain containing 2	6500	-0.008	0.2519	No
60	MMP10	MMP10 Entrez, Source	matrix metallopeptidase 10 (stromelysin 2)	6646	-0.010	0.2417	No
61	GAST	GAST Entrez, Source	gastrin	6705	-0.011	0.2383	No
62	ATP5I	ATP5I Entrez, Source	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	6710	-0.011	0.2388	No
63	CCK	CCK Entrez, Source	cholecystokinin	7195	-0.018	0.2038	No
64	PPBP	PPBP Entrez, Source	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	7274	-0.019	0.1995	No
65	BCL2L11	BCL2L11 Entrez, Source	BCL2-like 11 (apoptosis facilitator)	7593	-0.024	0.1774	No
66	H2AFX	H2AFX Entrez, Source	H2A histone family, member X	7594	-0.024	0.1794	No
67	HSP90AB1	HSP90AB1 Entrez, Source	heat shock protein 90kDa alpha (cytosolic), class B member 1	7690	-0.026	0.1744	No
68	EEF1A1	EEF1A1 Entrez, Source	eukaryotic translation elongation factor 1 alpha 1	7752	-0.027	0.1720	No
69	SURF1	SURF1 Entrez, Source	surfeit 1	8109	-0.032	0.1477	No
70	PIK3R3	PIK3R3 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)	8161	-0.033	0.1466	No
71	CSRP1	CSRP1 Entrez, Source	cysteine and glycine-rich protein 1	8162	-0.033	0.1494	No
72	DSCR1L1	DSCR1L1 Entrez, Source	Down syndrome critical region gene 1-like 1	8243	-0.035	0.1462	No
73	CDH16	CDH16 Entrez, Source	cadherin 16, KSP-cadherin	8265	-0.035	0.1475	No
74	SCG5	SCG5 Entrez, Source	secretogranin V (7B2 protein)	8494	-0.039	0.1335	No
75	HTR4	HTR4 Entrez, Source	5-hydroxytryptamine (serotonin) receptor 4	8591	-0.040	0.1295	No
76	CXCR3	CXCR3 Entrez, Source	chemokine (C-X-C motif) receptor 3	8633	-0.041	0.1298	No
77	PPP2R1A	PPP2R1A Entrez, Source	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	8698	-0.042	0.1285	No
78	RAP1A	RAP1A Entrez, Source	RAP1A, member of RAS oncogene family	8724	-0.043	0.1301	No
79	NR4A2	NR4A2 Entrez, Source	nuclear receptor subfamily 4, group A, member 2	8840	-0.044	0.1251	No
80	RALY	RALY Entrez, Source	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))	9125	-0.049	0.1077	No
81	RPL37	RPL37 Entrez, Source	ribosomal protein L37	9228	-0.051	0.1042	No
82	TITF1	TITF1 Entrez, Source	thyroid transcription factor 1	9298	-0.052	0.1033	No
83	PAX8	PAX8 Entrez, Source	paired box gene 8	9509	-0.056	0.0921	No
84	RPL31	RPL31 Entrez, Source	ribosomal protein L31	9579	-0.057	0.0916	No
85	TOM1	TOM1 Entrez, Source	target of myb1 (chicken)	9621	-0.058	0.0933	No
86	NDUFA1	NDUFA1 Entrez, Source	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa	9627	-0.058	0.0977	No
87	RPS17	RPS17 Entrez, Source	ribosomal protein S17	9686	-0.060	0.0982	No
88	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	9785	-0.062	0.0959	No
89	PGK1	PGK1 Entrez, Source	phosphoglycerate kinase 1	9880	-0.064	0.0941	No
90	GADD45A	GADD45A Entrez, Source	growth arrest and DNA-damage-inducible, alpha	10152	-0.069	0.0793	No
91	RPS21	RPS21 Entrez, Source	ribosomal protein S21	10215	-0.071	0.0805	No
92	TOB1	TOB1 Entrez, Source	transducer of ERBB2, 1	10294	-0.072	0.0806	No
93	ARHGDIA	ARHGDIA Entrez, Source	Rho GDP dissociation inhibitor (GDI) alpha	10450	-0.076	0.0751	No
94	RPS2	RPS2 Entrez, Source	ribosomal protein S2	10491	-0.078	0.0785	No
95	PFN1	PFN1 Entrez, Source	profilin 1	10821	-0.086	0.0607	No
96	TUBB3	TUBB3 Entrez, Source	tubulin, beta 3	11003	-0.091	0.0545	No
97	RPS23	RPS23 Entrez, Source	ribosomal protein S23	11016	-0.091	0.0611	No
98	CRYBA4	CRYBA4 Entrez, Source	crystallin, beta A4	11054	-0.092	0.0659	No
99	TACSTD2	TACSTD2 Entrez, Source	tumor-associated calcium signal transducer 2	11118	-0.094	0.0689	No
100	GAD2	GAD2 Entrez, Source	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	11228	-0.096	0.0686	No
101	RPS27	RPS27 Entrez, Source	ribosomal protein S27 (metallopanstimulin 1)	11346	-0.100	0.0680	No
102	TSC22D1	TSC22D1 Entrez, Source	TSC22 domain family, member 1	11438	-0.104	0.0697	No
103	MAOB	MAOB Entrez, Source	monoamine oxidase B	11520	-0.106	0.0724	No
104	PDLIM5	PDLIM5 Entrez, Source	PDZ and LIM domain 5	11910	-0.122	0.0530	No
105	EIF3S4	EIF3S4 Entrez, Source	eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa	12079	-0.131	0.0511	No
106	ID2	ID2 Entrez, Source	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	12777	-0.181	0.0134	No
107	HIST2H2AA3	HIST2H2AA3 Entrez, Source	histone cluster 2, H2aa3	13256	-0.354	0.0065	No