Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | UVB_NHEK3_C8 |
| Enrichment Score (ES) | 0.61454356 |
| Normalized Enrichment Score (NES) | 1.9552047 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.007206051 |
| FWER p-Value | 0.363 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 10 | 0.885 | 0.1477 | Yes |
| 2 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 29 | 0.753 | 0.2727 | Yes |
| 3 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 34 | 0.714 | 0.3920 | Yes |
| 4 | PTPRZ1 | PTPRZ1 Entrez, Source | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 68 | 0.591 | 0.4887 | Yes |
| 5 | HK1 | HK1 Entrez, Source | hexokinase 1 | 251 | 0.342 | 0.5324 | Yes |
| 6 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 525 | 0.222 | 0.5491 | Yes |
| 7 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 539 | 0.219 | 0.5848 | Yes |
| 8 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 1023 | 0.145 | 0.5727 | Yes |
| 9 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 1110 | 0.135 | 0.5889 | Yes |
| 10 | PON2 | PON2 Entrez, Source | paraoxonase 2 | 1301 | 0.120 | 0.5947 | Yes |
| 11 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.6145 | Yes |
| 12 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 1667 | 0.099 | 0.6040 | No |
| 13 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 1890 | 0.089 | 0.6023 | No |
| 14 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 2902 | 0.057 | 0.5359 | No |
| 15 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 3744 | 0.038 | 0.4789 | No |
| 16 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 4202 | 0.029 | 0.4495 | No |
| 17 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 4269 | 0.028 | 0.4492 | No |
| 18 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 4300 | 0.027 | 0.4515 | No |
| 19 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 4494 | 0.024 | 0.4410 | No |
| 20 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 4787 | 0.019 | 0.4221 | No |
| 21 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 4953 | 0.016 | 0.4124 | No |
| 22 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 5365 | 0.009 | 0.3830 | No |
| 23 | ST6GALNAC2 | ST6GALNAC2 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 5440 | 0.008 | 0.3788 | No |
| 24 | PFN2 | PFN2 Entrez, Source | profilin 2 | 5491 | 0.007 | 0.3763 | No |
| 25 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 5644 | 0.005 | 0.3657 | No |
| 26 | R3HDM1 | R3HDM1 Entrez, Source | R3H domain containing 1 | 6026 | -0.000 | 0.3371 | No |
| 27 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 6030 | -0.000 | 0.3370 | No |
| 28 | GLG1 | GLG1 Entrez, Source | golgi apparatus protein 1 | 6434 | -0.007 | 0.3078 | No |
| 29 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | 0.2910 | No |
| 30 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6731 | -0.011 | 0.2892 | No |
| 31 | TMED10 | TMED10 Entrez, Source | transmembrane emp24-like trafficking protein 10 (yeast) | 6987 | -0.015 | 0.2726 | No |
| 32 | FBN2 | FBN2 Entrez, Source | fibrillin 2 (congenital contractural arachnodactyly) | 7354 | -0.020 | 0.2484 | No |
| 33 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | 0.2494 | No |
| 34 | TOMM20 | TOMM20 Entrez, Source | translocase of outer mitochondrial membrane 20 homolog (yeast) | 8317 | -0.036 | 0.1857 | No |
| 35 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 8522 | -0.039 | 0.1769 | No |
| 36 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 8536 | -0.039 | 0.1825 | No |
| 37 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 8583 | -0.040 | 0.1858 | No |
| 38 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | 0.0515 | No |
| 39 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 11386 | -0.102 | 0.0055 | No |
| 40 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 11893 | -0.121 | -0.0123 | No |
| 41 | FASN | FASN Entrez, Source | fatty acid synthase | 12064 | -0.130 | -0.0033 | No |
| 42 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 12109 | -0.132 | 0.0156 | No |
| 43 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 12557 | -0.159 | 0.0086 | No |
| 44 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 13201 | -0.300 | 0.0106 | No |
