Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$ARNT_01 |
| Enrichment Score (ES) | -0.33305326 |
| Normalized Enrichment Score (NES) | -1.3319771 |
| Nominal p-value | 0.042666666 |
| FDR q-value | 0.41852435 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 71 | 0.581 | 0.0487 | No |
| 2 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 222 | 0.366 | 0.0714 | No |
| 3 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 659 | 0.195 | 0.0566 | No |
| 4 | TEF | TEF Entrez, Source | thyrotrophic embryonic factor | 701 | 0.186 | 0.0707 | No |
| 5 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 795 | 0.170 | 0.0795 | No |
| 6 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 886 | 0.157 | 0.0873 | No |
| 7 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 920 | 0.154 | 0.0991 | No |
| 8 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 1161 | 0.131 | 0.0932 | No |
| 9 | STX6 | STX6 Entrez, Source | syntaxin 6 | 1257 | 0.123 | 0.0974 | No |
| 10 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1506 | 0.108 | 0.0887 | No |
| 11 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0924 | No |
| 12 | CRY2 | CRY2 Entrez, Source | cryptochrome 2 (photolyase-like) | 1759 | 0.095 | 0.0882 | No |
| 13 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 1768 | 0.094 | 0.0963 | No |
| 14 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 1812 | 0.092 | 0.1016 | No |
| 15 | AP1GBP1 | AP1GBP1 Entrez, Source | AP1 gamma subunit binding protein 1 | 1896 | 0.089 | 0.1036 | No |
| 16 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1906 | 0.088 | 0.1112 | No |
| 17 | LTBR | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 1914 | 0.088 | 0.1188 | No |
| 18 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 1956 | 0.087 | 0.1238 | No |
| 19 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2085 | 0.081 | 0.1217 | No |
| 20 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 2086 | 0.081 | 0.1293 | No |
| 21 | NIT1 | NIT1 Entrez, Source | nitrilase 1 | 2199 | 0.077 | 0.1280 | No |
| 22 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2331 | 0.073 | 0.1249 | No |
| 23 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 2821 | 0.060 | 0.0934 | No |
| 24 | RNF44 | RNF44 Entrez, Source | ring finger protein 44 | 2838 | 0.059 | 0.0977 | No |
| 25 | TBC1D15 | TBC1D15 Entrez, Source | TBC1 domain family, member 15 | 2955 | 0.056 | 0.0942 | No |
| 26 | ZFP91 | ZFP91 Entrez, Source | zinc finger protein 91 homolog (mouse) | 3065 | 0.053 | 0.0908 | No |
| 27 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 3256 | 0.048 | 0.0809 | No |
| 28 | SLCO1C1 | SLCO1C1 Entrez, Source | solute carrier organic anion transporter family, member 1C1 | 3311 | 0.047 | 0.0812 | No |
| 29 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 3604 | 0.041 | 0.0630 | No |
| 30 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 3652 | 0.040 | 0.0631 | No |
| 31 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 3730 | 0.038 | 0.0608 | No |
| 32 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 3802 | 0.036 | 0.0588 | No |
| 33 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3826 | 0.036 | 0.0604 | No |
| 34 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 4026 | 0.032 | 0.0484 | No |
| 35 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 4283 | 0.028 | 0.0316 | No |
| 36 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 4552 | 0.022 | 0.0135 | No |
| 37 | PPP1R1B | PPP1R1B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) | 4556 | 0.022 | 0.0153 | No |
| 38 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 5224 | 0.011 | -0.0340 | No |
| 39 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 5609 | 0.006 | -0.0625 | No |
| 40 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 5636 | 0.005 | -0.0640 | No |
| 41 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.0721 | No |
| 42 | SCYL1 | SCYL1 Entrez, Source | SCY1-like 1 (S. cerevisiae) | 5974 | 0.000 | -0.0890 | No |
| 43 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 5985 | 0.000 | -0.0898 | No |
| 44 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 6173 | -0.003 | -0.1037 | No |
| 45 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 6403 | -0.006 | -0.1204 | No |
| 46 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 6447 | -0.007 | -0.1230 | No |
| 47 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 6499 | -0.008 | -0.1261 | No |
| 48 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 6500 | -0.008 | -0.1254 | No |
| 49 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6949 | -0.014 | -0.1579 | No |
| 50 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 7031 | -0.016 | -0.1626 | No |
| 51 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 7036 | -0.016 | -0.1615 | No |
| 52 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 7283 | -0.019 | -0.1783 | No |
| 53 | MTUS1 | MTUS1 Entrez, Source | mitochondrial tumor suppressor 1 | 7482 | -0.022 | -0.1912 | No |
| 54 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 7528 | -0.023 | -0.1924 | No |
| 55 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 7575 | -0.024 | -0.1937 | No |
| 56 | RHEBL1 | RHEBL1 Entrez, Source | Ras homolog enriched in brain like 1 | 8166 | -0.033 | -0.2352 | No |
| 57 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 8258 | -0.035 | -0.2388 | No |
| 58 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 8355 | -0.037 | -0.2427 | No |
| 59 | TIMM9 | TIMM9 Entrez, Source | translocase of inner mitochondrial membrane 9 homolog (yeast) | 8417 | -0.038 | -0.2438 | No |
| 60 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8457 | -0.038 | -0.2432 | No |
| 61 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 8718 | -0.043 | -0.2589 | No |
| 62 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 9001 | -0.047 | -0.2758 | No |
| 63 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 9044 | -0.048 | -0.2745 | No |
| 64 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 9165 | -0.050 | -0.2789 | No |
| 65 | TAC1 | TAC1 Entrez, Source | tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) | 9176 | -0.050 | -0.2750 | No |
| 66 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 9437 | -0.055 | -0.2895 | No |
| 67 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 9658 | -0.059 | -0.3007 | No |
| 68 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 9743 | -0.061 | -0.3014 | No |
| 69 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 9904 | -0.064 | -0.3075 | No |
| 70 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 10133 | -0.069 | -0.3183 | No |
| 71 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 10329 | -0.073 | -0.3262 | Yes |
| 72 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 10335 | -0.073 | -0.3198 | Yes |
| 73 | CELSR3 | CELSR3 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) | 10349 | -0.074 | -0.3139 | Yes |
| 74 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 10458 | -0.077 | -0.3150 | Yes |
| 75 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 10536 | -0.079 | -0.3135 | Yes |
| 76 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3144 | Yes |
| 77 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10670 | -0.082 | -0.3083 | Yes |
| 78 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 10710 | -0.083 | -0.3036 | Yes |
| 79 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 10713 | -0.083 | -0.2960 | Yes |
| 80 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 10867 | -0.087 | -0.2995 | Yes |
| 81 | SLC39A11 | SLC39A11 Entrez, Source | solute carrier family 39 (metal ion transporter), member 11 | 11126 | -0.094 | -0.3102 | Yes |
| 82 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3022 | Yes |
| 83 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 11350 | -0.100 | -0.3089 | Yes |
| 84 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 11429 | -0.103 | -0.3052 | Yes |
| 85 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 11627 | -0.110 | -0.3099 | Yes |
| 86 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11730 | -0.114 | -0.3070 | Yes |
| 87 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3036 | Yes |
| 88 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12031 | -0.128 | -0.3067 | Yes |
| 89 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12037 | -0.128 | -0.2952 | Yes |
| 90 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12051 | -0.129 | -0.2842 | Yes |
| 91 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 12056 | -0.129 | -0.2725 | Yes |
| 92 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 12149 | -0.134 | -0.2670 | Yes |
| 93 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 12187 | -0.136 | -0.2571 | Yes |
| 94 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12447 | -0.151 | -0.2627 | Yes |
| 95 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12458 | -0.152 | -0.2493 | Yes |
| 96 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12468 | -0.152 | -0.2358 | Yes |
| 97 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.2231 | Yes |
| 98 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.2098 | Yes |
| 99 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 12527 | -0.156 | -0.1968 | Yes |
| 100 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.1957 | Yes |
| 101 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 12994 | -0.216 | -0.1955 | Yes |
| 102 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13012 | -0.220 | -0.1763 | Yes |
| 103 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 13019 | -0.222 | -0.1561 | Yes |
| 104 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 13039 | -0.228 | -0.1364 | Yes |
| 105 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.1152 | Yes |
| 106 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 13102 | -0.253 | -0.0961 | Yes |
| 107 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13246 | -0.341 | -0.0752 | Yes |
| 108 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0401 | Yes |
| 109 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13309 | -0.475 | 0.0025 | Yes |
