Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F1DP1RB_01 |
| Enrichment Score (ES) | -0.38629106 |
| Normalized Enrichment Score (NES) | -1.485015 |
| Nominal p-value | 0.019753087 |
| FDR q-value | 0.26287332 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 85 | 0.548 | 0.0495 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0704 | No |
| 3 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 321 | 0.292 | 0.0956 | No |
| 4 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 404 | 0.258 | 0.1157 | No |
| 5 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 417 | 0.254 | 0.1407 | No |
| 6 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 783 | 0.172 | 0.1308 | No |
| 7 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1109 | 0.135 | 0.1200 | No |
| 8 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.1175 | No |
| 9 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.1069 | No |
| 10 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.1140 | No |
| 11 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 1881 | 0.089 | 0.1042 | No |
| 12 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2164 | 0.079 | 0.0909 | No |
| 13 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 2324 | 0.073 | 0.0863 | No |
| 14 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | 0.0833 | No |
| 15 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 2638 | 0.064 | 0.0763 | No |
| 16 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | 0.0724 | No |
| 17 | CORT | CORT Entrez, Source | cortistatin | 3577 | 0.041 | 0.0160 | No |
| 18 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3704 | 0.039 | 0.0104 | No |
| 19 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0136 | No |
| 20 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | -0.0226 | No |
| 21 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 4285 | 0.028 | -0.0242 | No |
| 22 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.0313 | No |
| 23 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 4711 | 0.020 | -0.0517 | No |
| 24 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.0644 | No |
| 25 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4937 | 0.016 | -0.0652 | No |
| 26 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4938 | 0.016 | -0.0636 | No |
| 27 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 5051 | 0.014 | -0.0706 | No |
| 28 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.0756 | No |
| 29 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.0815 | No |
| 30 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1141 | No |
| 31 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1210 | No |
| 32 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.1313 | No |
| 33 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 5921 | 0.001 | -0.1323 | No |
| 34 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1383 | No |
| 35 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.1584 | No |
| 36 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.1815 | No |
| 37 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.1870 | No |
| 38 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.1992 | No |
| 39 | CLTA | CLTA Entrez, Source | clathrin, light chain (Lca) | 7038 | -0.016 | -0.2108 | No |
| 40 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 7295 | -0.019 | -0.2282 | No |
| 41 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.2331 | No |
| 42 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 7634 | -0.025 | -0.2490 | No |
| 43 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 7701 | -0.026 | -0.2513 | No |
| 44 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 7770 | -0.027 | -0.2537 | No |
| 45 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7843 | -0.028 | -0.2563 | No |
| 46 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.2693 | No |
| 47 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.2852 | No |
| 48 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 8336 | -0.036 | -0.2827 | No |
| 49 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.2872 | No |
| 50 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.2922 | No |
| 51 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.2944 | No |
| 52 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.3004 | No |
| 53 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | -0.3249 | No |
| 54 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.3294 | No |
| 55 | LHX5 | LHX5 Entrez, Source | LIM homeobox 5 | 9552 | -0.057 | -0.3410 | No |
| 56 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.3476 | No |
| 57 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.3569 | No |
| 58 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 10099 | -0.068 | -0.3623 | No |
| 59 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.3738 | No |
| 60 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.3783 | Yes |
| 61 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10533 | -0.079 | -0.3714 | Yes |
| 62 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3718 | Yes |
| 63 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10670 | -0.082 | -0.3650 | Yes |
| 64 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.3581 | Yes |
| 65 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 10807 | -0.085 | -0.3581 | Yes |
| 66 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.3678 | Yes |
| 67 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3634 | Yes |
| 68 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3541 | Yes |
| 69 | RET | RET Entrez, Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 11258 | -0.097 | -0.3533 | Yes |
| 70 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.3444 | Yes |
| 71 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3588 | Yes |
| 72 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.3585 | Yes |
| 73 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3514 | Yes |
| 74 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11838 | -0.119 | -0.3397 | Yes |
| 75 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 11843 | -0.119 | -0.3278 | Yes |
| 76 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 12092 | -0.131 | -0.3332 | Yes |
| 77 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12203 | -0.137 | -0.3275 | Yes |
| 78 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.3293 | Yes |
| 79 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3167 | Yes |
| 80 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12490 | -0.154 | -0.3024 | Yes |
| 81 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.2944 | Yes |
| 82 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 12641 | -0.167 | -0.2799 | Yes |
| 83 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.2670 | Yes |
| 84 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.2528 | Yes |
| 85 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 12899 | -0.199 | -0.2430 | Yes |
| 86 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2236 | Yes |
| 87 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.2084 | Yes |
| 88 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1861 | Yes |
| 89 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.1637 | Yes |
| 90 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.1410 | Yes |
| 91 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.1203 | Yes |
| 92 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.0958 | Yes |
| 93 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0602 | Yes |
| 94 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
