Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F1_Q3 |
| Enrichment Score (ES) | -0.42481017 |
| Normalized Enrichment Score (NES) | -1.6450003 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.115721166 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 85 | 0.548 | 0.0527 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0757 | No |
| 3 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 321 | 0.292 | 0.1027 | No |
| 4 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 627 | 0.202 | 0.1014 | No |
| 5 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.0632 | No |
| 6 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0533 | No |
| 7 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.0610 | No |
| 8 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2164 | 0.079 | 0.0292 | No |
| 9 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.0333 | No |
| 10 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 2324 | 0.073 | 0.0334 | No |
| 11 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2377 | 0.072 | 0.0372 | No |
| 12 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | 0.0386 | No |
| 13 | ATP1B4 | ATP1B4 Entrez, Source | ATPase, (Na+)/K+ transporting, beta 4 polypeptide | 3144 | 0.051 | -0.0076 | No |
| 14 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3345 | 0.046 | -0.0177 | No |
| 15 | CORT | CORT Entrez, Source | cortistatin | 3577 | 0.041 | -0.0307 | No |
| 16 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0641 | No |
| 17 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 4114 | 0.031 | -0.0644 | No |
| 18 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | -0.0696 | No |
| 19 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.0810 | No |
| 20 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 4539 | 0.023 | -0.0880 | No |
| 21 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 4711 | 0.020 | -0.0987 | No |
| 22 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.1113 | No |
| 23 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4937 | 0.016 | -0.1121 | No |
| 24 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4938 | 0.016 | -0.1104 | No |
| 25 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4978 | 0.016 | -0.1116 | No |
| 26 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.1221 | No |
| 27 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 5185 | 0.012 | -0.1244 | No |
| 28 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 5224 | 0.011 | -0.1261 | No |
| 29 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.1252 | No |
| 30 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1578 | No |
| 31 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1647 | No |
| 32 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5892 | 0.002 | -0.1739 | No |
| 33 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 5912 | 0.001 | -0.1752 | No |
| 34 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 5921 | 0.001 | -0.1757 | No |
| 35 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.1811 | No |
| 36 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1816 | No |
| 37 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.2017 | No |
| 38 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.2248 | No |
| 39 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.2302 | No |
| 40 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 7125 | -0.017 | -0.2617 | No |
| 41 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 7388 | -0.021 | -0.2792 | No |
| 42 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 7754 | -0.027 | -0.3039 | No |
| 43 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7843 | -0.028 | -0.3075 | No |
| 44 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.3203 | No |
| 45 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 8193 | -0.034 | -0.3267 | No |
| 46 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.3323 | No |
| 47 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.3378 | No |
| 48 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3426 | No |
| 49 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 8892 | -0.045 | -0.3620 | No |
| 50 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 9066 | -0.048 | -0.3698 | No |
| 51 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | -0.3736 | No |
| 52 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.3777 | No |
| 53 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 9616 | -0.058 | -0.3937 | No |
| 54 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.3951 | No |
| 55 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.4040 | No |
| 56 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 10090 | -0.068 | -0.4083 | No |
| 57 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 10212 | -0.071 | -0.4098 | No |
| 58 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.4124 | No |
| 59 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.4164 | Yes |
| 60 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10533 | -0.079 | -0.4089 | Yes |
| 61 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.4089 | Yes |
| 62 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10670 | -0.082 | -0.4016 | Yes |
| 63 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 10807 | -0.085 | -0.4026 | Yes |
| 64 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.4118 | Yes |
| 65 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.4068 | Yes |
| 66 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3970 | Yes |
| 67 | ABCE1 | ABCE1 Entrez, Source | ATP-binding cassette, sub-family E (OABP), member 1 | 11152 | -0.095 | -0.3879 | Yes |
| 68 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.3864 | Yes |
| 69 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 11350 | -0.100 | -0.3813 | Yes |
| 70 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3893 | Yes |
| 71 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3930 | Yes |
| 72 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12203 | -0.137 | -0.4061 | Yes |
| 73 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 12441 | -0.151 | -0.4078 | Yes |
| 74 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12447 | -0.151 | -0.3918 | Yes |
| 75 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3770 | Yes |
| 76 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12523 | -0.156 | -0.3641 | Yes |
| 77 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12533 | -0.157 | -0.3478 | Yes |
| 78 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.3356 | Yes |
| 79 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.3243 | Yes |
| 80 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.3090 | Yes |
| 81 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2989 | Yes |
| 82 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12979 | -0.214 | -0.2805 | Yes |
| 83 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.2593 | Yes |
| 84 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.2356 | Yes |
| 85 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.2119 | Yes |
| 86 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.1878 | Yes |
| 87 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.1656 | Yes |
| 88 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 13158 | -0.275 | -0.1388 | Yes |
| 89 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 13197 | -0.299 | -0.1094 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.0771 | Yes |
| 91 | ASCL1 | ASCL1 Entrez, Source | achaete-scute complex-like 1 (Drosophila) | 13333 | -0.811 | 0.0007 | Yes |
