Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F1_Q4_01 |
| Enrichment Score (ES) | -0.4620173 |
| Normalized Enrichment Score (NES) | -1.7651824 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.062441513 |
| FWER p-Value | 0.964 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0177 | No |
| 2 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 404 | 0.258 | 0.0357 | No |
| 3 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 419 | 0.254 | 0.0630 | No |
| 4 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1109 | 0.135 | 0.0261 | No |
| 5 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 1294 | 0.120 | 0.0256 | No |
| 6 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.0117 | No |
| 7 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1703 | 0.097 | 0.0170 | No |
| 8 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1841 | 0.091 | 0.0168 | No |
| 9 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 2059 | 0.083 | 0.0097 | No |
| 10 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.0062 | No |
| 11 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | -0.0040 | No |
| 12 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 2754 | 0.061 | -0.0194 | No |
| 13 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | -0.0140 | No |
| 14 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 2900 | 0.057 | -0.0171 | No |
| 15 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 3527 | 0.042 | -0.0596 | No |
| 16 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 3689 | 0.039 | -0.0674 | No |
| 17 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3704 | 0.039 | -0.0642 | No |
| 18 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0879 | No |
| 19 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.1491 | No |
| 20 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 5124 | 0.013 | -0.1643 | No |
| 21 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.1709 | No |
| 22 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 5545 | 0.007 | -0.1939 | No |
| 23 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.2026 | No |
| 24 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.2095 | No |
| 25 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.2198 | No |
| 26 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.2270 | No |
| 27 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6078 | -0.001 | -0.2326 | No |
| 28 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 6190 | -0.003 | -0.2406 | No |
| 29 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.2464 | No |
| 30 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.2528 | No |
| 31 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.2688 | No |
| 32 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.2742 | No |
| 33 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.2862 | No |
| 34 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.2865 | No |
| 35 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7161 | -0.018 | -0.3052 | No |
| 36 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 7295 | -0.019 | -0.3130 | No |
| 37 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 7364 | -0.020 | -0.3159 | No |
| 38 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.3154 | No |
| 39 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 7529 | -0.023 | -0.3233 | No |
| 40 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 7770 | -0.027 | -0.3384 | No |
| 41 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 7823 | -0.028 | -0.3393 | No |
| 42 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 8161 | -0.033 | -0.3610 | No |
| 43 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.3655 | No |
| 44 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.3649 | No |
| 45 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8361 | -0.037 | -0.3638 | No |
| 46 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.3660 | No |
| 47 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3707 | No |
| 48 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.3724 | No |
| 49 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.3781 | No |
| 50 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 8995 | -0.047 | -0.3878 | No |
| 51 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9125 | -0.049 | -0.3921 | No |
| 52 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.4008 | No |
| 53 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.4398 | No |
| 54 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.4336 | No |
| 55 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 10090 | -0.068 | -0.4365 | No |
| 56 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 10429 | -0.075 | -0.4536 | Yes |
| 57 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 10475 | -0.077 | -0.4484 | Yes |
| 58 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.4428 | Yes |
| 59 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.4361 | Yes |
| 60 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10598 | -0.080 | -0.4310 | Yes |
| 61 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.4257 | Yes |
| 62 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.4196 | Yes |
| 63 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.4133 | Yes |
| 64 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 11042 | -0.092 | -0.4264 | Yes |
| 65 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.4226 | Yes |
| 66 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.4124 | Yes |
| 67 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11173 | -0.095 | -0.4045 | Yes |
| 68 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 11226 | -0.096 | -0.3977 | Yes |
| 69 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11338 | -0.100 | -0.3949 | Yes |
| 70 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.4033 | Yes |
| 71 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.4018 | Yes |
| 72 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3936 | Yes |
| 73 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11838 | -0.119 | -0.3808 | Yes |
| 74 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.3867 | Yes |
| 75 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 12212 | -0.137 | -0.3788 | Yes |
| 76 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.3784 | Yes |
| 77 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3643 | Yes |
| 78 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.3485 | Yes |
| 79 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.3390 | Yes |
| 80 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.3270 | Yes |
| 81 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.3111 | Yes |
| 82 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 12899 | -0.199 | -0.2994 | Yes |
| 83 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2780 | Yes |
| 84 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12967 | -0.213 | -0.2580 | Yes |
| 85 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.2371 | Yes |
| 86 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.2126 | Yes |
| 87 | NUP155 | NUP155 Entrez, Source | nucleoporin 155kDa | 13054 | -0.235 | -0.1881 | Yes |
| 88 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.1641 | Yes |
| 89 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 13158 | -0.275 | -0.1363 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.1058 | Yes |
| 91 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0662 | Yes |
| 92 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
