Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F1_Q6 |
| Enrichment Score (ES) | -0.37995136 |
| Normalized Enrichment Score (NES) | -1.4579821 |
| Nominal p-value | 0.017456358 |
| FDR q-value | 0.2791613 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 85 | 0.548 | 0.0587 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0853 | No |
| 3 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 321 | 0.292 | 0.1155 | No |
| 4 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 627 | 0.202 | 0.1164 | No |
| 5 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 666 | 0.194 | 0.1367 | No |
| 6 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.1027 | No |
| 7 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0939 | No |
| 8 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.1027 | No |
| 9 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 1737 | 0.096 | 0.1060 | No |
| 10 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2164 | 0.079 | 0.0832 | No |
| 11 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.0881 | No |
| 12 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 2324 | 0.073 | 0.0890 | No |
| 13 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | 0.0872 | No |
| 14 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 2911 | 0.057 | 0.0599 | No |
| 15 | CORT | CORT Entrez, Source | cortistatin | 3577 | 0.041 | 0.0146 | No |
| 16 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0185 | No |
| 17 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | -0.0270 | No |
| 18 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.0382 | No |
| 19 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 4711 | 0.020 | -0.0582 | No |
| 20 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.0706 | No |
| 21 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4937 | 0.016 | -0.0712 | No |
| 22 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4938 | 0.016 | -0.0693 | No |
| 23 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.0826 | No |
| 24 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.0883 | No |
| 25 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 5412 | 0.009 | -0.1009 | No |
| 26 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1197 | No |
| 27 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 5683 | 0.005 | -0.1201 | No |
| 28 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 5699 | 0.004 | -0.1208 | No |
| 29 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.1240 | No |
| 30 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1249 | No |
| 31 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 5921 | 0.001 | -0.1364 | No |
| 32 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.1418 | No |
| 33 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1423 | No |
| 34 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.1623 | No |
| 35 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.1686 | No |
| 36 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.1732 | No |
| 37 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.1836 | No |
| 38 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.1890 | No |
| 39 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 6693 | -0.011 | -0.1884 | No |
| 40 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.1996 | No |
| 41 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.1998 | No |
| 42 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 7388 | -0.021 | -0.2351 | No |
| 43 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7843 | -0.028 | -0.2660 | No |
| 44 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.2784 | No |
| 45 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.2938 | No |
| 46 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.2988 | No |
| 47 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3032 | No |
| 48 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.3150 | No |
| 49 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 9066 | -0.048 | -0.3296 | No |
| 50 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | -0.3328 | No |
| 51 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.3363 | No |
| 52 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 9690 | -0.060 | -0.3571 | No |
| 53 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.3523 | No |
| 54 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.3605 | No |
| 55 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 9944 | -0.065 | -0.3534 | No |
| 56 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.3460 | No |
| 57 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.3675 | No |
| 58 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.3706 | Yes |
| 59 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10533 | -0.079 | -0.3624 | Yes |
| 60 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.3540 | Yes |
| 61 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3520 | Yes |
| 62 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10670 | -0.082 | -0.3438 | Yes |
| 63 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.3384 | Yes |
| 64 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 10807 | -0.085 | -0.3339 | Yes |
| 65 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 10963 | -0.089 | -0.3349 | Yes |
| 66 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.3314 | Yes |
| 67 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3254 | Yes |
| 68 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.3243 | Yes |
| 69 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 11511 | -0.106 | -0.3297 | Yes |
| 70 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3243 | Yes |
| 71 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.3219 | Yes |
| 72 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3129 | Yes |
| 73 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12203 | -0.137 | -0.3245 | Yes |
| 74 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.3238 | Yes |
| 75 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3086 | Yes |
| 76 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12533 | -0.157 | -0.2946 | Yes |
| 77 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.2769 | Yes |
| 78 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.2617 | Yes |
| 79 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.2485 | Yes |
| 80 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.2293 | Yes |
| 81 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.2103 | Yes |
| 82 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.1980 | Yes |
| 83 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12979 | -0.214 | -0.1772 | Yes |
| 84 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.1536 | Yes |
| 85 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1275 | Yes |
| 86 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.1013 | Yes |
| 87 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.0747 | Yes |
| 88 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 13109 | -0.256 | -0.0493 | Yes |
| 89 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.0192 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | 0.0104 | Yes |
