Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F1_Q6_01 |
| Enrichment Score (ES) | -0.36487448 |
| Normalized Enrichment Score (NES) | -1.4093732 |
| Nominal p-value | 0.043583535 |
| FDR q-value | 0.3330008 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 164 | 0.430 | 0.0385 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0709 | No |
| 3 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 321 | 0.292 | 0.1009 | No |
| 4 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 419 | 0.254 | 0.1236 | No |
| 5 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 627 | 0.202 | 0.1318 | No |
| 6 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 666 | 0.194 | 0.1519 | No |
| 7 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 797 | 0.170 | 0.1622 | No |
| 8 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1210 | 0.127 | 0.1461 | No |
| 9 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.1531 | No |
| 10 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.1407 | No |
| 11 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 1737 | 0.096 | 0.1440 | No |
| 12 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2164 | 0.079 | 0.1211 | No |
| 13 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.1260 | No |
| 14 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | 0.0915 | No |
| 15 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 2911 | 0.057 | 0.0879 | No |
| 16 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 3297 | 0.047 | 0.0645 | No |
| 17 | FZD1 | FZD1 Entrez, Source | frizzled homolog 1 (Drosophila) | 3493 | 0.043 | 0.0549 | No |
| 18 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 3527 | 0.042 | 0.0574 | No |
| 19 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | 0.0082 | No |
| 20 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.0030 | No |
| 21 | HR | HR Entrez, Source | hairless homolog (mouse) | 5020 | 0.015 | -0.0469 | No |
| 22 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.0541 | No |
| 23 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 5224 | 0.011 | -0.0593 | No |
| 24 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.0584 | No |
| 25 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 5412 | 0.009 | -0.0710 | No |
| 26 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.0898 | No |
| 27 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 5683 | 0.005 | -0.0902 | No |
| 28 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.0946 | No |
| 29 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 5770 | 0.003 | -0.0959 | No |
| 30 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.1058 | No |
| 31 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 5914 | 0.001 | -0.1063 | No |
| 32 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.1122 | No |
| 33 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1127 | No |
| 34 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.1327 | No |
| 35 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.1390 | No |
| 36 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.1437 | No |
| 37 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 6525 | -0.008 | -0.1490 | No |
| 38 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.1530 | No |
| 39 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 6622 | -0.009 | -0.1540 | No |
| 40 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.1572 | No |
| 41 | FAF1 | FAF1 Entrez, Source | Fas (TNFRSF6) associated factor 1 | 6848 | -0.013 | -0.1681 | No |
| 42 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.1676 | No |
| 43 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.1678 | No |
| 44 | SPHK2 | SPHK2 Entrez, Source | sphingosine kinase 2 | 6993 | -0.015 | -0.1739 | No |
| 45 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7161 | -0.018 | -0.1845 | No |
| 46 | DHH | DHH Entrez, Source | desert hedgehog homolog (Drosophila) | 7363 | -0.020 | -0.1972 | No |
| 47 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 7610 | -0.024 | -0.2129 | No |
| 48 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7843 | -0.028 | -0.2271 | No |
| 49 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.2554 | No |
| 50 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.2639 | No |
| 51 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.2683 | No |
| 52 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.2698 | No |
| 53 | TCF8 | TCF8 Entrez, Source | transcription factor 8 (represses interleukin 2 expression) | 8965 | -0.047 | -0.2876 | No |
| 54 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 8995 | -0.047 | -0.2842 | No |
| 55 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | -0.2928 | No |
| 56 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.2964 | No |
| 57 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 9616 | -0.058 | -0.3117 | No |
| 58 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.3125 | No |
| 59 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.3513 | No |
| 60 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10533 | -0.079 | -0.3556 | Yes |
| 61 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.3472 | Yes |
| 62 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3453 | Yes |
| 63 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10670 | -0.082 | -0.3371 | Yes |
| 64 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.3289 | Yes |
| 65 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.3220 | Yes |
| 66 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 10963 | -0.089 | -0.3288 | Yes |
| 67 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3303 | Yes |
| 68 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3195 | Yes |
| 69 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11173 | -0.095 | -0.3109 | Yes |
| 70 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 11226 | -0.096 | -0.3035 | Yes |
| 71 | ENPP1 | ENPP1 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 11335 | -0.100 | -0.2998 | Yes |
| 72 | MGAT2 | MGAT2 Entrez, Source | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 11343 | -0.100 | -0.2885 | Yes |
| 73 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 11478 | -0.105 | -0.2862 | Yes |
| 74 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.2833 | Yes |
| 75 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.2810 | Yes |
| 76 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.2720 | Yes |
| 77 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12051 | -0.129 | -0.2732 | Yes |
| 78 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.2622 | Yes |
| 79 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 12376 | -0.147 | -0.2646 | Yes |
| 80 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12406 | -0.149 | -0.2492 | Yes |
| 81 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.2371 | Yes |
| 82 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12533 | -0.157 | -0.2218 | Yes |
| 83 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.2158 | Yes |
| 84 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.1968 | Yes |
| 85 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.1846 | Yes |
| 86 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12967 | -0.213 | -0.1632 | Yes |
| 87 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.1406 | Yes |
| 88 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1146 | Yes |
| 89 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.0886 | Yes |
| 90 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.0621 | Yes |
| 91 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.0383 | Yes |
| 92 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | 0.0041 | Yes |
