Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F4DP1_01 |
| Enrichment Score (ES) | -0.39009032 |
| Normalized Enrichment Score (NES) | -1.5191253 |
| Nominal p-value | 0.004938272 |
| FDR q-value | 0.21415043 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 85 | 0.548 | 0.0510 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0728 | No |
| 3 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 321 | 0.292 | 0.0989 | No |
| 4 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 417 | 0.254 | 0.1183 | No |
| 5 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 666 | 0.194 | 0.1199 | No |
| 6 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 783 | 0.172 | 0.1292 | No |
| 7 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.1024 | No |
| 8 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0922 | No |
| 9 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.0995 | No |
| 10 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 1737 | 0.096 | 0.1014 | No |
| 11 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 1881 | 0.089 | 0.1000 | No |
| 12 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2164 | 0.079 | 0.0869 | No |
| 13 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 2324 | 0.073 | 0.0825 | No |
| 14 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | 0.0798 | No |
| 15 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 2638 | 0.064 | 0.0729 | No |
| 16 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 2911 | 0.057 | 0.0584 | No |
| 17 | CORT | CORT Entrez, Source | cortistatin | 3577 | 0.041 | 0.0125 | No |
| 18 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0211 | No |
| 19 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | -0.0300 | No |
| 20 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.0415 | No |
| 21 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 4711 | 0.020 | -0.0618 | No |
| 22 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.0745 | No |
| 23 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4937 | 0.016 | -0.0753 | No |
| 24 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4938 | 0.016 | -0.0736 | No |
| 25 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 5051 | 0.014 | -0.0806 | No |
| 26 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.0856 | No |
| 27 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.0914 | No |
| 28 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 5412 | 0.009 | -0.1042 | No |
| 29 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1230 | No |
| 30 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 5683 | 0.005 | -0.1235 | No |
| 31 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 5699 | 0.004 | -0.1242 | No |
| 32 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.1275 | No |
| 33 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1284 | No |
| 34 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 5921 | 0.001 | -0.1399 | No |
| 35 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1459 | No |
| 36 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.1660 | No |
| 37 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.1778 | No |
| 38 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.1883 | No |
| 39 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.1938 | No |
| 40 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 6693 | -0.011 | -0.1934 | No |
| 41 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.2066 | No |
| 42 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 7634 | -0.025 | -0.2603 | No |
| 43 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7843 | -0.028 | -0.2731 | No |
| 44 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.2860 | No |
| 45 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.3019 | No |
| 46 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 8336 | -0.036 | -0.2992 | No |
| 47 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.3036 | No |
| 48 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3085 | No |
| 49 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | -0.3499 | No |
| 50 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.3542 | No |
| 51 | LHX5 | LHX5 Entrez, Source | LIM homeobox 5 | 9552 | -0.057 | -0.3657 | No |
| 52 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 9690 | -0.060 | -0.3698 | No |
| 53 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.3658 | No |
| 54 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.3749 | No |
| 55 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 9944 | -0.065 | -0.3688 | No |
| 56 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.3623 | No |
| 57 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 10099 | -0.068 | -0.3663 | No |
| 58 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.3776 | No |
| 59 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.3819 | Yes |
| 60 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10533 | -0.079 | -0.3747 | Yes |
| 61 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.3675 | Yes |
| 62 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3666 | Yes |
| 63 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10670 | -0.082 | -0.3595 | Yes |
| 64 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.3554 | Yes |
| 65 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 10807 | -0.085 | -0.3520 | Yes |
| 66 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 10963 | -0.089 | -0.3544 | Yes |
| 67 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.3522 | Yes |
| 68 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3474 | Yes |
| 69 | RET | RET Entrez, Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 11258 | -0.097 | -0.3468 | Yes |
| 70 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.3375 | Yes |
| 71 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 11511 | -0.106 | -0.3444 | Yes |
| 72 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3405 | Yes |
| 73 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.3398 | Yes |
| 74 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3324 | Yes |
| 75 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 11843 | -0.119 | -0.3207 | Yes |
| 76 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 12092 | -0.131 | -0.3257 | Yes |
| 77 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12203 | -0.137 | -0.3197 | Yes |
| 78 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3238 | Yes |
| 79 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12490 | -0.154 | -0.3091 | Yes |
| 80 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12533 | -0.157 | -0.2958 | Yes |
| 81 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.2804 | Yes |
| 82 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.2675 | Yes |
| 83 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.2567 | Yes |
| 84 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.2401 | Yes |
| 85 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.2236 | Yes |
| 86 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2141 | Yes |
| 87 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.1984 | Yes |
| 88 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1754 | Yes |
| 89 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.1525 | Yes |
| 90 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.1291 | Yes |
| 91 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 13109 | -0.256 | -0.1073 | Yes |
| 92 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.0809 | Yes |
| 93 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.0555 | Yes |
| 94 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
