Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F_01 |
| Enrichment Score (ES) | -0.48201364 |
| Normalized Enrichment Score (NES) | -1.5328333 |
| Nominal p-value | 0.02690583 |
| FDR q-value | 0.19771692 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 419 | 0.254 | 0.0557 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0037 | No |
| 3 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.0351 | No |
| 4 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 3417 | 0.045 | -0.0837 | No |
| 5 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3826 | 0.036 | -0.1020 | No |
| 6 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 4926 | 0.016 | -0.1790 | No |
| 7 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.2331 | No |
| 8 | NLGN3 | NLGN3 Entrez, Source | neuroligin 3 | 5755 | 0.003 | -0.2384 | No |
| 9 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.2491 | No |
| 10 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 5921 | 0.001 | -0.2498 | No |
| 11 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.3177 | No |
| 12 | GATA6 | GATA6 Entrez, Source | GATA binding protein 6 | 7526 | -0.023 | -0.3577 | No |
| 13 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 7594 | -0.024 | -0.3545 | No |
| 14 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 8161 | -0.033 | -0.3856 | No |
| 15 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.4026 | No |
| 16 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.4044 | No |
| 17 | PPP1R10 | PPP1R10 Entrez, Source | protein phosphatase 1, regulatory subunit 10 | 9241 | -0.051 | -0.4202 | No |
| 18 | ECEL1 | ECEL1 Entrez, Source | endothelin converting enzyme-like 1 | 9833 | -0.063 | -0.4431 | No |
| 19 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10352 | -0.074 | -0.4567 | Yes |
| 20 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.4442 | Yes |
| 21 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.4293 | Yes |
| 22 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.4269 | Yes |
| 23 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 11219 | -0.096 | -0.4004 | Yes |
| 24 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3922 | Yes |
| 25 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3680 | Yes |
| 26 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12051 | -0.129 | -0.3401 | Yes |
| 27 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12267 | -0.140 | -0.3080 | Yes |
| 28 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 12376 | -0.147 | -0.2656 | Yes |
| 29 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 12573 | -0.160 | -0.2255 | Yes |
| 30 | ADNP | ADNP Entrez, Source | activity-dependent neuroprotector | 12610 | -0.164 | -0.1719 | Yes |
| 31 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12967 | -0.213 | -0.1256 | Yes |
| 32 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.0531 | Yes |
| 33 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | 0.0234 | Yes |
