Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F_Q3 |
| Enrichment Score (ES) | -0.49257398 |
| Normalized Enrichment Score (NES) | -1.8826888 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02748247 |
| FWER p-Value | 0.569 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0155 | No |
| 2 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 404 | 0.258 | 0.0318 | No |
| 3 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 417 | 0.254 | 0.0576 | No |
| 4 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 627 | 0.202 | 0.0630 | No |
| 5 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 783 | 0.172 | 0.0695 | No |
| 6 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1109 | 0.135 | 0.0591 | No |
| 7 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1629 | 0.101 | 0.0306 | No |
| 8 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 1881 | 0.089 | 0.0210 | No |
| 9 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.0036 | No |
| 10 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2377 | 0.072 | -0.0007 | No |
| 11 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2458 | 0.069 | 0.0006 | No |
| 12 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | -0.0167 | No |
| 13 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3345 | 0.046 | -0.0550 | No |
| 14 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3704 | 0.039 | -0.0779 | No |
| 15 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 4114 | 0.031 | -0.1056 | No |
| 16 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 4285 | 0.028 | -0.1155 | No |
| 17 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 4539 | 0.023 | -0.1322 | No |
| 18 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4978 | 0.016 | -0.1636 | No |
| 19 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 5185 | 0.012 | -0.1779 | No |
| 20 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.2138 | No |
| 21 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.2207 | No |
| 22 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5892 | 0.002 | -0.2300 | No |
| 23 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.2308 | No |
| 24 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 5912 | 0.001 | -0.2311 | No |
| 25 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.2372 | No |
| 26 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.2377 | No |
| 27 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.2577 | No |
| 28 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.2641 | No |
| 29 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.2866 | No |
| 30 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.2988 | No |
| 31 | CLTA | CLTA Entrez, Source | clathrin, light chain (Lca) | 7038 | -0.016 | -0.3103 | No |
| 32 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 7125 | -0.017 | -0.3150 | No |
| 33 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7161 | -0.018 | -0.3158 | No |
| 34 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 7295 | -0.019 | -0.3238 | No |
| 35 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 7388 | -0.021 | -0.3285 | No |
| 36 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.3264 | No |
| 37 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 7634 | -0.025 | -0.3422 | No |
| 38 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 7701 | -0.026 | -0.3444 | No |
| 39 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 7754 | -0.027 | -0.3456 | No |
| 40 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 7770 | -0.027 | -0.3439 | No |
| 41 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 8193 | -0.034 | -0.3722 | No |
| 42 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.3745 | No |
| 43 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.3741 | No |
| 44 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8361 | -0.037 | -0.3732 | No |
| 45 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 8448 | -0.038 | -0.3757 | No |
| 46 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3807 | No |
| 47 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.3827 | No |
| 48 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.3886 | No |
| 49 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 8892 | -0.045 | -0.3910 | No |
| 50 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 9066 | -0.048 | -0.3990 | No |
| 51 | LHX5 | LHX5 Entrez, Source | LIM homeobox 5 | 9552 | -0.057 | -0.4297 | No |
| 52 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.4516 | No |
| 53 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 10090 | -0.068 | -0.4561 | No |
| 54 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 10212 | -0.071 | -0.4578 | No |
| 55 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | -0.4726 | No |
| 56 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.4739 | No |
| 57 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.4683 | No |
| 58 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.4625 | No |
| 59 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.4827 | Yes |
| 60 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.4731 | Yes |
| 61 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11173 | -0.095 | -0.4659 | Yes |
| 62 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11338 | -0.100 | -0.4677 | Yes |
| 63 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 11350 | -0.100 | -0.4580 | Yes |
| 64 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.4663 | Yes |
| 65 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.4655 | Yes |
| 66 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.4581 | Yes |
| 67 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11838 | -0.119 | -0.4460 | Yes |
| 68 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 12092 | -0.131 | -0.4513 | Yes |
| 69 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.4609 | Yes |
| 70 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.4478 | Yes |
| 71 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12490 | -0.154 | -0.4331 | Yes |
| 72 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12523 | -0.156 | -0.4191 | Yes |
| 73 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.4081 | Yes |
| 74 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.3973 | Yes |
| 75 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.3825 | Yes |
| 76 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 12899 | -0.199 | -0.3721 | Yes |
| 77 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.3520 | Yes |
| 78 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 12979 | -0.214 | -0.3342 | Yes |
| 79 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.3139 | Yes |
| 80 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.2908 | Yes |
| 81 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.2702 | Yes |
| 82 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 13158 | -0.275 | -0.2442 | Yes |
| 83 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 13197 | -0.299 | -0.2157 | Yes |
| 84 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.1843 | Yes |
| 85 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.1474 | Yes |
| 86 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | -0.0840 | Yes |
| 87 | ASCL1 | ASCL1 Entrez, Source | achaete-scute complex-like 1 (Drosophila) | 13333 | -0.811 | 0.0007 | Yes |
