Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F_Q4_01 |
| Enrichment Score (ES) | -0.42989454 |
| Normalized Enrichment Score (NES) | -1.6035951 |
| Nominal p-value | 0.004651163 |
| FDR q-value | 0.13602394 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0209 | No |
| 2 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 297 | 0.311 | 0.0558 | No |
| 3 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 404 | 0.258 | 0.0790 | No |
| 4 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 419 | 0.254 | 0.1087 | No |
| 5 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1109 | 0.135 | 0.0731 | No |
| 6 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 1294 | 0.120 | 0.0738 | No |
| 7 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1703 | 0.097 | 0.0547 | No |
| 8 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.0251 | No |
| 9 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2377 | 0.072 | 0.0220 | No |
| 10 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | -0.0005 | No |
| 11 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 2900 | 0.057 | -0.0030 | No |
| 12 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 2935 | 0.057 | 0.0012 | No |
| 13 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3345 | 0.046 | -0.0240 | No |
| 14 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 3527 | 0.042 | -0.0325 | No |
| 15 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 3689 | 0.039 | -0.0400 | No |
| 16 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3704 | 0.039 | -0.0364 | No |
| 17 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0598 | No |
| 18 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 4469 | 0.024 | -0.0872 | No |
| 19 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.1178 | No |
| 20 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 5124 | 0.013 | -0.1329 | No |
| 21 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.1394 | No |
| 22 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 5545 | 0.007 | -0.1623 | No |
| 23 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1710 | No |
| 24 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1779 | No |
| 25 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5892 | 0.002 | -0.1871 | No |
| 26 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.1878 | No |
| 27 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.1944 | No |
| 28 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1950 | No |
| 29 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6078 | -0.001 | -0.2005 | No |
| 30 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 6190 | -0.003 | -0.2085 | No |
| 31 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.2143 | No |
| 32 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.2206 | No |
| 33 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.2365 | No |
| 34 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.2418 | No |
| 35 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.2537 | No |
| 36 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 6887 | -0.013 | -0.2539 | No |
| 37 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7161 | -0.018 | -0.2723 | No |
| 38 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.2870 | No |
| 39 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 7754 | -0.027 | -0.3112 | No |
| 40 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 7770 | -0.027 | -0.3091 | No |
| 41 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 7823 | -0.028 | -0.3096 | No |
| 42 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 8161 | -0.033 | -0.3310 | No |
| 43 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.3352 | No |
| 44 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.3343 | No |
| 45 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8361 | -0.037 | -0.3328 | No |
| 46 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3437 | No |
| 47 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.3450 | No |
| 48 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.3502 | No |
| 49 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 9112 | -0.049 | -0.3681 | No |
| 50 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9320 | -0.053 | -0.3773 | No |
| 51 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 9451 | -0.055 | -0.3805 | No |
| 52 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.4090 | No |
| 53 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.4022 | No |
| 54 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 10090 | -0.068 | -0.4044 | No |
| 55 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 10429 | -0.075 | -0.4208 | Yes |
| 56 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 10475 | -0.077 | -0.4148 | Yes |
| 57 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.4106 | Yes |
| 58 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10598 | -0.080 | -0.4047 | Yes |
| 59 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3987 | Yes |
| 60 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.3918 | Yes |
| 61 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.3847 | Yes |
| 62 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 11042 | -0.092 | -0.3970 | Yes |
| 63 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3922 | Yes |
| 64 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3812 | Yes |
| 65 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11173 | -0.095 | -0.3724 | Yes |
| 66 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 11219 | -0.096 | -0.3641 | Yes |
| 67 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 11226 | -0.096 | -0.3529 | Yes |
| 68 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 11294 | -0.098 | -0.3460 | Yes |
| 69 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3567 | Yes |
| 70 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.3541 | Yes |
| 71 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.3643 | Yes |
| 72 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12284 | -0.141 | -0.3600 | Yes |
| 73 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.3528 | Yes |
| 74 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 12441 | -0.151 | -0.3353 | Yes |
| 75 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3190 | Yes |
| 76 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.3017 | Yes |
| 77 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.2969 | Yes |
| 78 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.2793 | Yes |
| 79 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 12899 | -0.199 | -0.2657 | Yes |
| 80 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2424 | Yes |
| 81 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12967 | -0.213 | -0.2204 | Yes |
| 82 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1974 | Yes |
| 83 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.1708 | Yes |
| 84 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.1460 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.1157 | Yes |
| 86 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0722 | Yes |
| 87 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
