Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$E2F_Q6_01 |
| Enrichment Score (ES) | -0.41592747 |
| Normalized Enrichment Score (NES) | -1.5729011 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.15412985 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 260 | 0.335 | 0.0207 | No |
| 2 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 297 | 0.311 | 0.0554 | No |
| 3 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 404 | 0.258 | 0.0784 | No |
| 4 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 600 | 0.206 | 0.0886 | No |
| 5 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 627 | 0.202 | 0.1109 | No |
| 6 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 1294 | 0.120 | 0.0751 | No |
| 7 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 1504 | 0.108 | 0.0724 | No |
| 8 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1703 | 0.097 | 0.0691 | No |
| 9 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 1768 | 0.094 | 0.0757 | No |
| 10 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 2220 | 0.077 | 0.0509 | No |
| 11 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2377 | 0.072 | 0.0477 | No |
| 12 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | 0.0253 | No |
| 13 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 2900 | 0.057 | 0.0227 | No |
| 14 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 2935 | 0.057 | 0.0269 | No |
| 15 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 3345 | 0.046 | 0.0016 | No |
| 16 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | -0.0053 | No |
| 17 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3704 | 0.039 | -0.0155 | No |
| 18 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 4066 | 0.032 | -0.0389 | No |
| 19 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.1000 | No |
| 20 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4978 | 0.016 | -0.1037 | No |
| 21 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 5051 | 0.014 | -0.1074 | No |
| 22 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 5230 | 0.011 | -0.1195 | No |
| 23 | SNCB | SNCB Entrez, Source | synuclein, beta | 5417 | 0.008 | -0.1325 | No |
| 24 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 5545 | 0.007 | -0.1413 | No |
| 25 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 5669 | 0.005 | -0.1500 | No |
| 26 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 5766 | 0.003 | -0.1569 | No |
| 27 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5892 | 0.002 | -0.1661 | No |
| 28 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | -0.1668 | No |
| 29 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 5921 | 0.001 | -0.1678 | No |
| 30 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.1732 | No |
| 31 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.1737 | No |
| 32 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 6190 | -0.003 | -0.1875 | No |
| 33 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.1933 | No |
| 34 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.1996 | No |
| 35 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6594 | -0.009 | -0.2155 | No |
| 36 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.2208 | No |
| 37 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6862 | -0.013 | -0.2327 | No |
| 38 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 7180 | -0.018 | -0.2545 | No |
| 39 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.2677 | No |
| 40 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 7770 | -0.027 | -0.2931 | No |
| 41 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 7823 | -0.028 | -0.2937 | No |
| 42 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 8274 | -0.035 | -0.3234 | No |
| 43 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 8320 | -0.036 | -0.3224 | No |
| 44 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8361 | -0.037 | -0.3210 | No |
| 45 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8570 | -0.040 | -0.3319 | No |
| 46 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 8795 | -0.044 | -0.3435 | No |
| 47 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 8813 | -0.044 | -0.3395 | No |
| 48 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 9066 | -0.048 | -0.3527 | No |
| 49 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 9112 | -0.049 | -0.3502 | No |
| 50 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9125 | -0.049 | -0.3452 | No |
| 51 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 9451 | -0.055 | -0.3630 | No |
| 52 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9934 | -0.065 | -0.3916 | No |
| 53 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 10014 | -0.067 | -0.3895 | No |
| 54 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 10090 | -0.068 | -0.3870 | No |
| 55 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 10475 | -0.077 | -0.4067 | Yes |
| 56 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.4025 | Yes |
| 57 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.4004 | Yes |
| 58 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.3935 | Yes |
| 59 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.3865 | Yes |
| 60 | HTR2C | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C | 10920 | -0.088 | -0.3900 | Yes |
| 61 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 11042 | -0.092 | -0.3881 | Yes |
| 62 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.3784 | Yes |
| 63 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.3722 | Yes |
| 64 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3612 | Yes |
| 65 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11173 | -0.095 | -0.3525 | Yes |
| 66 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 11219 | -0.096 | -0.3443 | Yes |
| 67 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 11294 | -0.098 | -0.3380 | Yes |
| 68 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3488 | Yes |
| 69 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.3463 | Yes |
| 70 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.3565 | Yes |
| 71 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12284 | -0.141 | -0.3523 | Yes |
| 72 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.3452 | Yes |
| 73 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 12441 | -0.151 | -0.3278 | Yes |
| 74 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 12470 | -0.153 | -0.3115 | Yes |
| 75 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.2944 | Yes |
| 76 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12490 | -0.154 | -0.2758 | Yes |
| 77 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.2711 | Yes |
| 78 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 12759 | -0.178 | -0.2536 | Yes |
| 79 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2410 | Yes |
| 80 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12967 | -0.213 | -0.2191 | Yes |
| 81 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1963 | Yes |
| 82 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.1698 | Yes |
| 83 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13118 | -0.258 | -0.1452 | Yes |
| 84 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.1150 | Yes |
| 85 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0718 | Yes |
| 86 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
