Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$MAX_01 |
| Enrichment Score (ES) | -0.3652051 |
| Normalized Enrichment Score (NES) | -1.4301106 |
| Nominal p-value | 0.021276595 |
| FDR q-value | 0.31831345 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 47 | 0.660 | 0.0498 | No |
| 2 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 173 | 0.414 | 0.0738 | No |
| 3 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 265 | 0.332 | 0.0937 | No |
| 4 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 300 | 0.310 | 0.1161 | No |
| 5 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 659 | 0.195 | 0.1048 | No |
| 6 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 846 | 0.163 | 0.1039 | No |
| 7 | MAX | MAX Entrez, Source | MYC associated factor X | 1040 | 0.142 | 0.1008 | No |
| 8 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 1161 | 0.131 | 0.1024 | No |
| 9 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.1048 | No |
| 10 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.0887 | No |
| 11 | LZTFL1 | LZTFL1 Entrez, Source | leucine zipper transcription factor-like 1 | 1710 | 0.097 | 0.0872 | No |
| 12 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 1768 | 0.094 | 0.0905 | No |
| 13 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 1874 | 0.090 | 0.0898 | No |
| 14 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1906 | 0.088 | 0.0946 | No |
| 15 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 1956 | 0.087 | 0.0979 | No |
| 16 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2085 | 0.081 | 0.0948 | No |
| 17 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 2086 | 0.081 | 0.1014 | No |
| 18 | NIT1 | NIT1 Entrez, Source | nitrilase 1 | 2199 | 0.077 | 0.0992 | No |
| 19 | DZIP1 | DZIP1 Entrez, Source | DAZ interacting protein 1 | 2229 | 0.076 | 0.1032 | No |
| 20 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 2373 | 0.072 | 0.0981 | No |
| 21 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 2623 | 0.064 | 0.0845 | No |
| 22 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 2821 | 0.060 | 0.0744 | No |
| 23 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 2882 | 0.058 | 0.0746 | No |
| 24 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 3256 | 0.048 | 0.0503 | No |
| 25 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 3604 | 0.041 | 0.0273 | No |
| 26 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 3628 | 0.040 | 0.0289 | No |
| 27 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 3730 | 0.038 | 0.0243 | No |
| 28 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3826 | 0.036 | 0.0200 | No |
| 29 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3861 | 0.035 | 0.0203 | No |
| 30 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 4026 | 0.032 | 0.0105 | No |
| 31 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 4029 | 0.032 | 0.0130 | No |
| 32 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 4175 | 0.030 | 0.0044 | No |
| 33 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 4283 | 0.028 | -0.0014 | No |
| 34 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 4498 | 0.023 | -0.0157 | No |
| 35 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 4552 | 0.022 | -0.0179 | No |
| 36 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 4972 | 0.016 | -0.0483 | No |
| 37 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 5402 | 0.009 | -0.0800 | No |
| 38 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 5636 | 0.005 | -0.0972 | No |
| 39 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.1053 | No |
| 40 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 5871 | 0.002 | -0.1144 | No |
| 41 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6078 | -0.001 | -0.1299 | No |
| 42 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 6173 | -0.003 | -0.1368 | No |
| 43 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 6319 | -0.005 | -0.1473 | No |
| 44 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 6499 | -0.008 | -0.1602 | No |
| 45 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6949 | -0.014 | -0.1930 | No |
| 46 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 7031 | -0.016 | -0.1979 | No |
| 47 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 7269 | -0.019 | -0.2142 | No |
| 48 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 7842 | -0.028 | -0.2552 | No |
| 49 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 7946 | -0.030 | -0.2606 | No |
| 50 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 8084 | -0.032 | -0.2683 | No |
| 51 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 8258 | -0.035 | -0.2786 | No |
| 52 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 8355 | -0.037 | -0.2829 | No |
| 53 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 8430 | -0.038 | -0.2854 | No |
| 54 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8457 | -0.038 | -0.2843 | No |
| 55 | GGN | GGN Entrez, Source | gametogenetin | 8632 | -0.041 | -0.2941 | No |
| 56 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 9044 | -0.048 | -0.3213 | No |
| 57 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 9234 | -0.051 | -0.3315 | No |
| 58 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 9437 | -0.055 | -0.3423 | No |
| 59 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 9515 | -0.056 | -0.3436 | No |
| 60 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 9658 | -0.059 | -0.3495 | No |
| 61 | GNAS | GNAS Entrez, Source | GNAS complex locus | 9688 | -0.060 | -0.3469 | No |
| 62 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 9743 | -0.061 | -0.3461 | No |
| 63 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 9892 | -0.064 | -0.3521 | No |
| 64 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 9904 | -0.064 | -0.3477 | No |
| 65 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.3459 | No |
| 66 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 10207 | -0.071 | -0.3595 | Yes |
| 67 | IPO13 | IPO13 Entrez, Source | importin 13 | 10265 | -0.072 | -0.3580 | Yes |
| 68 | GUCY1A2 | GUCY1A2 Entrez, Source | guanylate cyclase 1, soluble, alpha 2 | 10348 | -0.074 | -0.3583 | Yes |
| 69 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 10416 | -0.075 | -0.3573 | Yes |
| 70 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 10458 | -0.077 | -0.3542 | Yes |
| 71 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 10491 | -0.078 | -0.3503 | Yes |
| 72 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 10495 | -0.078 | -0.3443 | Yes |
| 73 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10615 | -0.080 | -0.3468 | Yes |
| 74 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.3428 | Yes |
| 75 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 10710 | -0.083 | -0.3406 | Yes |
| 76 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 10713 | -0.083 | -0.3340 | Yes |
| 77 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 10892 | -0.088 | -0.3404 | Yes |
| 78 | ACY1 | ACY1 Entrez, Source | aminoacylase 1 | 10962 | -0.089 | -0.3384 | Yes |
| 79 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 11053 | -0.092 | -0.3378 | Yes |
| 80 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 11058 | -0.092 | -0.3306 | Yes |
| 81 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 11221 | -0.096 | -0.3351 | Yes |
| 82 | TIMM10 | TIMM10 Entrez, Source | translocase of inner mitochondrial membrane 10 homolog (yeast) | 11292 | -0.098 | -0.3324 | Yes |
| 83 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 11411 | -0.103 | -0.3331 | Yes |
| 84 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 11429 | -0.103 | -0.3260 | Yes |
| 85 | RAI14 | RAI14 Entrez, Source | retinoic acid induced 14 | 11447 | -0.104 | -0.3189 | Yes |
| 86 | FKBP11 | FKBP11 Entrez, Source | FK506 binding protein 11, 19 kDa | 11643 | -0.111 | -0.3247 | Yes |
| 87 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 11661 | -0.111 | -0.3170 | Yes |
| 88 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3203 | Yes |
| 89 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12031 | -0.128 | -0.3249 | Yes |
| 90 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12051 | -0.129 | -0.3159 | Yes |
| 91 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 12056 | -0.129 | -0.3058 | Yes |
| 92 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 12187 | -0.136 | -0.3046 | Yes |
| 93 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 12408 | -0.149 | -0.3092 | Yes |
| 94 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12447 | -0.151 | -0.2999 | Yes |
| 95 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12458 | -0.152 | -0.2884 | Yes |
| 96 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12468 | -0.152 | -0.2768 | Yes |
| 97 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.2659 | Yes |
| 98 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.2545 | Yes |
| 99 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 12663 | -0.169 | -0.2527 | Yes |
| 100 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.2434 | Yes |
| 101 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12783 | -0.183 | -0.2326 | Yes |
| 102 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 12994 | -0.216 | -0.2310 | Yes |
| 103 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 13004 | -0.219 | -0.2140 | Yes |
| 104 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13012 | -0.220 | -0.1967 | Yes |
| 105 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 13019 | -0.222 | -0.1792 | Yes |
| 106 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 13039 | -0.228 | -0.1623 | Yes |
| 107 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.1439 | Yes |
| 108 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 13074 | -0.242 | -0.1266 | Yes |
| 109 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 13197 | -0.299 | -0.1117 | Yes |
| 110 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0853 | Yes |
| 111 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13309 | -0.475 | -0.0484 | Yes |
| 112 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
