Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$MYCMAX_01 |
| Enrichment Score (ES) | -0.46932718 |
| Normalized Enrichment Score (NES) | -1.8378693 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.040970605 |
| FWER p-Value | 0.773 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 173 | 0.414 | 0.0217 | No |
| 2 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 659 | 0.195 | 0.0015 | No |
| 3 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 710 | 0.184 | 0.0131 | No |
| 4 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1126 | 0.134 | -0.0070 | No |
| 5 | SLC6A15 | SLC6A15 Entrez, Source | solute carrier family 6, member 15 | 1417 | 0.112 | -0.0194 | No |
| 6 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1506 | 0.108 | -0.0170 | No |
| 7 | GPC3 | GPC3 Entrez, Source | glypican 3 | 1656 | 0.100 | -0.0199 | No |
| 8 | CRMP1 | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 1742 | 0.095 | -0.0183 | No |
| 9 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 1874 | 0.090 | -0.0207 | No |
| 10 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1906 | 0.088 | -0.0156 | No |
| 11 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 1956 | 0.087 | -0.0120 | No |
| 12 | RAMP2 | RAMP2 Entrez, Source | receptor (calcitonin) activity modifying protein 2 | 1999 | 0.085 | -0.0080 | No |
| 13 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 2086 | 0.081 | -0.0077 | No |
| 14 | G6PC3 | G6PC3 Entrez, Source | glucose 6 phosphatase, catalytic, 3 | 2090 | 0.081 | -0.0011 | No |
| 15 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 2174 | 0.078 | -0.0008 | No |
| 16 | CGREF1 | CGREF1 Entrez, Source | cell growth regulator with EF-hand domain 1 | 2198 | 0.077 | 0.0040 | No |
| 17 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 2623 | 0.064 | -0.0227 | No |
| 18 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 2792 | 0.060 | -0.0303 | No |
| 19 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 2882 | 0.058 | -0.0322 | No |
| 20 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 2900 | 0.057 | -0.0286 | No |
| 21 | ARL3 | ARL3 Entrez, Source | ADP-ribosylation factor-like 3 | 3079 | 0.052 | -0.0377 | No |
| 22 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 3256 | 0.048 | -0.0470 | No |
| 23 | MPP3 | MPP3 Entrez, Source | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | 3553 | 0.042 | -0.0658 | No |
| 24 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 3604 | 0.041 | -0.0662 | No |
| 25 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 3730 | 0.038 | -0.0724 | No |
| 26 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3826 | 0.036 | -0.0766 | No |
| 27 | DIABLO | DIABLO Entrez, Source | diablo homolog (Drosophila) | 4020 | 0.032 | -0.0885 | No |
| 28 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 4026 | 0.032 | -0.0861 | No |
| 29 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 4029 | 0.032 | -0.0835 | No |
| 30 | GPM6B | GPM6B Entrez, Source | glycoprotein M6B | 4058 | 0.032 | -0.0830 | No |
| 31 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 4552 | 0.022 | -0.1184 | No |
| 32 | STXBP2 | STXBP2 Entrez, Source | syntaxin binding protein 2 | 4719 | 0.020 | -0.1293 | No |
| 33 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4726 | 0.020 | -0.1281 | No |
| 34 | KCMF1 | KCMF1 Entrez, Source | potassium channel modulatory factor 1 | 5258 | 0.011 | -0.1673 | No |
| 35 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 5695 | 0.004 | -0.1999 | No |
| 36 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 5748 | 0.003 | -0.2036 | No |
| 37 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 6046 | -0.001 | -0.2260 | No |
| 38 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6078 | -0.001 | -0.2282 | No |
| 39 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 6406 | -0.006 | -0.2524 | No |
| 40 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 6499 | -0.008 | -0.2587 | No |
| 41 | GPS1 | GPS1 Entrez, Source | G protein pathway suppressor 1 | 6668 | -0.010 | -0.2705 | No |
| 42 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 6904 | -0.014 | -0.2872 | No |
| 43 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6949 | -0.014 | -0.2893 | No |
| 44 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 7036 | -0.016 | -0.2945 | No |
| 45 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 7269 | -0.019 | -0.3104 | No |
| 46 | PPARGC1B | PPARGC1B Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, beta | 7905 | -0.029 | -0.3559 | No |
| 47 | PITX3 | PITX3 Entrez, Source | paired-like homeodomain transcription factor 3 | 8020 | -0.031 | -0.3619 | No |
| 48 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 8084 | -0.032 | -0.3640 | No |
| 49 | RHEBL1 | RHEBL1 Entrez, Source | Ras homolog enriched in brain like 1 | 8166 | -0.033 | -0.3673 | No |
| 50 | WDR23 | WDR23 Entrez, Source | WD repeat domain 23 | 8174 | -0.033 | -0.3650 | No |
| 51 | TIMM9 | TIMM9 Entrez, Source | translocase of inner mitochondrial membrane 9 homolog (yeast) | 8417 | -0.038 | -0.3802 | No |
| 52 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 8430 | -0.038 | -0.3779 | No |
| 53 | SC65 | SC65 Entrez, Source | - | 8463 | -0.038 | -0.3771 | No |
| 54 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 8467 | -0.038 | -0.3741 | No |
| 55 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 8646 | -0.041 | -0.3841 | No |
| 56 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 8663 | -0.041 | -0.3818 | No |
| 57 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 8872 | -0.045 | -0.3938 | No |
| 58 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 9437 | -0.055 | -0.4318 | No |
| 59 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 9515 | -0.056 | -0.4329 | No |
| 60 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 9658 | -0.059 | -0.4387 | No |
| 61 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 9743 | -0.061 | -0.4399 | No |
| 62 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 9950 | -0.065 | -0.4500 | No |
| 63 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 10207 | -0.071 | -0.4634 | Yes |
| 64 | IPO13 | IPO13 Entrez, Source | importin 13 | 10265 | -0.072 | -0.4617 | Yes |
| 65 | SLC12A5 | SLC12A5 Entrez, Source | solute carrier family 12, (potassium-chloride transporter) member 5 | 10280 | -0.072 | -0.4567 | Yes |
| 66 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 10416 | -0.075 | -0.4606 | Yes |
| 67 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 10458 | -0.077 | -0.4572 | Yes |
| 68 | KCNN4 | KCNN4 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 10587 | -0.080 | -0.4602 | Yes |
| 69 | POU3F2 | POU3F2 Entrez, Source | POU domain, class 3, transcription factor 2 | 10612 | -0.080 | -0.4553 | Yes |
| 70 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.4512 | Yes |
| 71 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 10710 | -0.083 | -0.4488 | Yes |
| 72 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.4433 | Yes |
| 73 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10821 | -0.086 | -0.4428 | Yes |
| 74 | ACY1 | ACY1 Entrez, Source | aminoacylase 1 | 10962 | -0.089 | -0.4458 | Yes |
| 75 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 11058 | -0.092 | -0.4453 | Yes |
| 76 | LYAR | LYAR Entrez, Source | - | 11179 | -0.095 | -0.4464 | Yes |
| 77 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 11221 | -0.096 | -0.4414 | Yes |
| 78 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 11248 | -0.097 | -0.4352 | Yes |
| 79 | PUS1 | PUS1 Entrez, Source | pseudouridylate synthase 1 | 11257 | -0.097 | -0.4276 | Yes |
| 80 | TIMM10 | TIMM10 Entrez, Source | translocase of inner mitochondrial membrane 10 homolog (yeast) | 11292 | -0.098 | -0.4219 | Yes |
| 81 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 11429 | -0.103 | -0.4235 | Yes |
| 82 | RAI14 | RAI14 Entrez, Source | retinoic acid induced 14 | 11447 | -0.104 | -0.4161 | Yes |
| 83 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 11627 | -0.110 | -0.4203 | Yes |
| 84 | FKBP11 | FKBP11 Entrez, Source | FK506 binding protein 11, 19 kDa | 11643 | -0.111 | -0.4121 | Yes |
| 85 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 11661 | -0.111 | -0.4040 | Yes |
| 86 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11730 | -0.114 | -0.3996 | Yes |
| 87 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3973 | Yes |
| 88 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12051 | -0.129 | -0.4029 | Yes |
| 89 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 12056 | -0.129 | -0.3924 | Yes |
| 90 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.3855 | Yes |
| 91 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 12187 | -0.136 | -0.3796 | Yes |
| 92 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12468 | -0.152 | -0.3879 | Yes |
| 93 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.3765 | Yes |
| 94 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12500 | -0.155 | -0.3643 | Yes |
| 95 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.3516 | Yes |
| 96 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 12509 | -0.155 | -0.3387 | Yes |
| 97 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 12663 | -0.169 | -0.3361 | Yes |
| 98 | XTP3TPA | XTP3TPA Entrez, Source | - | 12705 | -0.174 | -0.3246 | Yes |
| 99 | ATAD3A | ATAD3A Entrez, Source | ATPase family, AAA domain containing 3A | 12723 | -0.175 | -0.3111 | Yes |
| 100 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12730 | -0.176 | -0.2968 | Yes |
| 101 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12799 | -0.185 | -0.2864 | Yes |
| 102 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2781 | Yes |
| 103 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 12951 | -0.209 | -0.2631 | Yes |
| 104 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13012 | -0.220 | -0.2491 | Yes |
| 105 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 13029 | -0.225 | -0.2314 | Yes |
| 106 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 13039 | -0.228 | -0.2130 | Yes |
| 107 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.1938 | Yes |
| 108 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 13074 | -0.242 | -0.1758 | Yes |
| 109 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 13102 | -0.253 | -0.1566 | Yes |
| 110 | DAZAP1 | DAZAP1 Entrez, Source | DAZ associated protein 1 | 13172 | -0.281 | -0.1382 | Yes |
| 111 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 13197 | -0.299 | -0.1149 | Yes |
| 112 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13288 | -0.411 | -0.0871 | Yes |
| 113 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 13302 | -0.454 | -0.0500 | Yes |
| 114 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13326 | -0.630 | 0.0012 | Yes |
