Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | V$USF_01 |
| Enrichment Score (ES) | -0.3209179 |
| Normalized Enrichment Score (NES) | -1.2796425 |
| Nominal p-value | 0.06403941 |
| FDR q-value | 0.5151914 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 47 | 0.660 | 0.0507 | No |
| 2 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 71 | 0.581 | 0.0968 | No |
| 3 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 265 | 0.332 | 0.1095 | No |
| 4 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 300 | 0.310 | 0.1324 | No |
| 5 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 639 | 0.199 | 0.1232 | No |
| 6 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 668 | 0.193 | 0.1369 | No |
| 7 | TEF | TEF Entrez, Source | thyrotrophic embryonic factor | 701 | 0.186 | 0.1498 | No |
| 8 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 710 | 0.184 | 0.1643 | No |
| 9 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 795 | 0.170 | 0.1719 | No |
| 10 | MAX | MAX Entrez, Source | MYC associated factor X | 1040 | 0.142 | 0.1652 | No |
| 11 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 1161 | 0.131 | 0.1669 | No |
| 12 | STX6 | STX6 Entrez, Source | syntaxin 6 | 1257 | 0.123 | 0.1698 | No |
| 13 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.1797 | No |
| 14 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1506 | 0.108 | 0.1701 | No |
| 15 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.1727 | No |
| 16 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 1768 | 0.094 | 0.1667 | No |
| 17 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1906 | 0.088 | 0.1637 | No |
| 18 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 1956 | 0.087 | 0.1671 | No |
| 19 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 2086 | 0.081 | 0.1640 | No |
| 20 | NIT1 | NIT1 Entrez, Source | nitrilase 1 | 2199 | 0.077 | 0.1619 | No |
| 21 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 2821 | 0.060 | 0.1199 | No |
| 22 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 3256 | 0.048 | 0.0911 | No |
| 23 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 3388 | 0.045 | 0.0849 | No |
| 24 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 3604 | 0.041 | 0.0720 | No |
| 25 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 3730 | 0.038 | 0.0657 | No |
| 26 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3861 | 0.035 | 0.0588 | No |
| 27 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 4026 | 0.032 | 0.0490 | No |
| 28 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 4175 | 0.030 | 0.0403 | No |
| 29 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 4213 | 0.029 | 0.0399 | No |
| 30 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 4283 | 0.028 | 0.0369 | No |
| 31 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 4477 | 0.024 | 0.0243 | No |
| 32 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 4552 | 0.022 | 0.0206 | No |
| 33 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 4718 | 0.020 | 0.0097 | No |
| 34 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 5528 | 0.007 | -0.0509 | No |
| 35 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 5636 | 0.005 | -0.0585 | No |
| 36 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5733 | 0.004 | -0.0655 | No |
| 37 | SCYL1 | SCYL1 Entrez, Source | SCY1-like 1 (S. cerevisiae) | 5974 | 0.000 | -0.0836 | No |
| 38 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 6173 | -0.003 | -0.0983 | No |
| 39 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 6319 | -0.005 | -0.1088 | No |
| 40 | ADAM10 | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 6375 | -0.006 | -0.1125 | No |
| 41 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 6499 | -0.008 | -0.1212 | No |
| 42 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 6500 | -0.008 | -0.1206 | No |
| 43 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 6904 | -0.014 | -0.1499 | No |
| 44 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6949 | -0.014 | -0.1520 | No |
| 45 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 7208 | -0.018 | -0.1700 | No |
| 46 | VPS33A | VPS33A Entrez, Source | vacuolar protein sorting 33 homolog A (S. cerevisiae) | 7773 | -0.027 | -0.2104 | No |
| 47 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 7946 | -0.030 | -0.2210 | No |
| 48 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 8084 | -0.032 | -0.2287 | No |
| 49 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 8258 | -0.035 | -0.2389 | No |
| 50 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 8355 | -0.037 | -0.2431 | No |
| 51 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8457 | -0.038 | -0.2476 | No |
| 52 | GGN | GGN Entrez, Source | gametogenetin | 8632 | -0.041 | -0.2574 | No |
| 53 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 8958 | -0.047 | -0.2781 | No |
| 54 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 9001 | -0.047 | -0.2774 | No |
| 55 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 9044 | -0.048 | -0.2766 | No |
| 56 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 9092 | -0.049 | -0.2762 | No |
| 57 | SLC12A6 | SLC12A6 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 6 | 9210 | -0.051 | -0.2808 | No |
| 58 | RAB24 | RAB24 Entrez, Source | RAB24, member RAS oncogene family | 9508 | -0.056 | -0.2987 | No |
| 59 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 9515 | -0.056 | -0.2945 | No |
| 60 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 9538 | -0.056 | -0.2915 | No |
| 61 | TOM1 | TOM1 Entrez, Source | target of myb1 (chicken) | 9621 | -0.058 | -0.2929 | No |
| 62 | GNAS | GNAS Entrez, Source | GNAS complex locus | 9688 | -0.060 | -0.2930 | No |
| 63 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 9743 | -0.061 | -0.2921 | No |
| 64 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 9892 | -0.064 | -0.2980 | No |
| 65 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 9904 | -0.064 | -0.2936 | No |
| 66 | SC5DL | SC5DL Entrez, Source | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like | 9978 | -0.066 | -0.2937 | No |
| 67 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10173 | -0.070 | -0.3026 | No |
| 68 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 10335 | -0.073 | -0.3087 | No |
| 69 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 10458 | -0.077 | -0.3116 | No |
| 70 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 10495 | -0.078 | -0.3080 | No |
| 71 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 10536 | -0.079 | -0.3045 | No |
| 72 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10615 | -0.080 | -0.3038 | No |
| 73 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 10649 | -0.081 | -0.2997 | No |
| 74 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 10710 | -0.083 | -0.2974 | No |
| 75 | HTF9C | HTF9C Entrez, Source | - | 10732 | -0.084 | -0.2921 | No |
| 76 | ATIC | ATIC Entrez, Source | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 10742 | -0.084 | -0.2859 | No |
| 77 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 11053 | -0.092 | -0.3018 | No |
| 78 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 11136 | -0.094 | -0.3002 | No |
| 79 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 11411 | -0.103 | -0.3125 | Yes |
| 80 | RAI14 | RAI14 Entrez, Source | retinoic acid induced 14 | 11447 | -0.104 | -0.3066 | Yes |
| 81 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.3100 | Yes |
| 82 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 11661 | -0.111 | -0.3044 | Yes |
| 83 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 11832 | -0.118 | -0.3075 | Yes |
| 84 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 11863 | -0.120 | -0.2999 | Yes |
| 85 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 11911 | -0.122 | -0.2935 | Yes |
| 86 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12031 | -0.128 | -0.2919 | Yes |
| 87 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 12038 | -0.128 | -0.2819 | Yes |
| 88 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12051 | -0.129 | -0.2722 | Yes |
| 89 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 12056 | -0.129 | -0.2618 | Yes |
| 90 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 12149 | -0.134 | -0.2578 | Yes |
| 91 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 12187 | -0.136 | -0.2494 | Yes |
| 92 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 12408 | -0.149 | -0.2538 | Yes |
| 93 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12447 | -0.151 | -0.2442 | Yes |
| 94 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12458 | -0.152 | -0.2325 | Yes |
| 95 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.2221 | Yes |
| 96 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.2105 | Yes |
| 97 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 12527 | -0.156 | -0.1993 | Yes |
| 98 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 12663 | -0.169 | -0.1955 | Yes |
| 99 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12783 | -0.183 | -0.1895 | Yes |
| 100 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 12788 | -0.183 | -0.1748 | Yes |
| 101 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 12951 | -0.209 | -0.1698 | Yes |
| 102 | CUL5 | CUL5 Entrez, Source | cullin 5 | 12964 | -0.212 | -0.1533 | Yes |
| 103 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 12994 | -0.216 | -0.1377 | Yes |
| 104 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 13004 | -0.219 | -0.1204 | Yes |
| 105 | GTF2A1 | GTF2A1 Entrez, Source | general transcription factor IIA, 1, 19/37kDa | 13010 | -0.220 | -0.1026 | Yes |
| 106 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 13019 | -0.222 | -0.0850 | Yes |
| 107 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.0677 | Yes |
| 108 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 13197 | -0.299 | -0.0547 | Yes |
| 109 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 13228 | -0.322 | -0.0305 | Yes |
| 110 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13309 | -0.475 | 0.0025 | Yes |
