Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | VEGF_MMMEC_3HRS_UP |
| Enrichment Score (ES) | 0.5708611 |
| Normalized Enrichment Score (NES) | 1.8665596 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.017262414 |
| FWER p-Value | 0.78 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MGP | MGP Entrez, Source | matrix Gla protein | 52 | 0.634 | 0.0937 | Yes |
| 2 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 93 | 0.529 | 0.1723 | Yes |
| 3 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 145 | 0.452 | 0.2381 | Yes |
| 4 | BGN | BGN Entrez, Source | biglycan | 175 | 0.408 | 0.2989 | Yes |
| 5 | CD9 | CD9 Entrez, Source | CD9 molecule | 283 | 0.320 | 0.3402 | Yes |
| 6 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 411 | 0.256 | 0.3701 | Yes |
| 7 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 516 | 0.223 | 0.3967 | Yes |
| 8 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 548 | 0.217 | 0.4278 | Yes |
| 9 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 709 | 0.184 | 0.4441 | Yes |
| 10 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 721 | 0.182 | 0.4714 | Yes |
| 11 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 908 | 0.156 | 0.4814 | Yes |
| 12 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1007 | 0.146 | 0.4965 | Yes |
| 13 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 1041 | 0.142 | 0.5159 | Yes |
| 14 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1043 | 0.142 | 0.5378 | Yes |
| 15 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 1241 | 0.124 | 0.5421 | Yes |
| 16 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1402 | 0.113 | 0.5475 | Yes |
| 17 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1506 | 0.108 | 0.5564 | Yes |
| 18 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 1532 | 0.106 | 0.5709 | Yes |
| 19 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 2769 | 0.061 | 0.4873 | No |
| 20 | CEACAM1 | CEACAM1 Entrez, Source | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 3419 | 0.045 | 0.4453 | No |
| 21 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 3567 | 0.041 | 0.4406 | No |
| 22 | HCLS1 | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 4075 | 0.031 | 0.4073 | No |
| 23 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 4386 | 0.026 | 0.3879 | No |
| 24 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 4498 | 0.023 | 0.3832 | No |
| 25 | HEMGN | HEMGN Entrez, Source | hemogen | 4584 | 0.022 | 0.3802 | No |
| 26 | GALNT1 | GALNT1 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) | 4813 | 0.018 | 0.3658 | No |
| 27 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4938 | 0.016 | 0.3590 | No |
| 28 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 5143 | 0.012 | 0.3455 | No |
| 29 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 5673 | 0.005 | 0.3065 | No |
| 30 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 6239 | -0.004 | 0.2645 | No |
| 31 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 6300 | -0.005 | 0.2607 | No |
| 32 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 6646 | -0.010 | 0.2362 | No |
| 33 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 6909 | -0.014 | 0.2186 | No |
| 34 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 6935 | -0.014 | 0.2189 | No |
| 35 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 7266 | -0.019 | 0.1971 | No |
| 36 | ANGPT2 | ANGPT2 Entrez, Source | angiopoietin 2 | 7458 | -0.022 | 0.1861 | No |
| 37 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 8124 | -0.033 | 0.1411 | No |
| 38 | VWF | VWF Entrez, Source | von Willebrand factor | 8376 | -0.037 | 0.1279 | No |
| 39 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 8911 | -0.046 | 0.0947 | No |
| 40 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 9336 | -0.053 | 0.0710 | No |
| 41 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 9424 | -0.055 | 0.0729 | No |
| 42 | NDUFA1 | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 9627 | -0.058 | 0.0667 | No |
| 43 | PRKCI | PRKCI Entrez, Source | protein kinase C, iota | 10240 | -0.071 | 0.0316 | No |
| 44 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10603 | -0.080 | 0.0167 | No |
| 45 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 11104 | -0.093 | -0.0065 | No |
| 46 | SLC6A8 | SLC6A8 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 11161 | -0.095 | 0.0039 | No |
| 47 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.0237 | No |
| 48 | RALA | RALA Entrez, Source | v-ral simian leukemia viral oncogene homolog A (ras related) | 12043 | -0.128 | -0.0247 | No |
| 49 | RBX1 | RBX1 Entrez, Source | ring-box 1 | 12058 | -0.129 | -0.0059 | No |
| 50 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 12073 | -0.130 | 0.0131 | No |
| 51 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | -0.0017 | No |
| 52 | TRIM23 | TRIM23 Entrez, Source | tripartite motif-containing 23 | 12662 | -0.169 | 0.0203 | No |
| 53 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12902 | -0.200 | 0.0331 | No |
