Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetVEGF_MMMEC_ALL_UP
Enrichment Score (ES)0.61833924
Normalized Enrichment Score (NES)2.1075249
Nominal p-value0.0
FDR q-value0.0011050116
FWER p-Value0.027
Table: GSEA Results Summary



Fig 1: Enrichment plot: VEGF_MMMEC_ALL_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 261.1540.1224Yes
2MGPMGP
Entrez,  Source
matrix Gla protein520.6340.1865Yes
3ANKRD1ANKRD1
Entrez,  Source
ankyrin repeat domain 1 (cardiac muscle)930.5290.2398Yes
4CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 21450.4520.2841Yes
5BGNBGN
Entrez,  Source
biglycan1750.4080.3254Yes
6CD9CD9
Entrez,  Source
CD9 molecule2830.3200.3515Yes
7FOXO1AFOXO1A
Entrez,  Source
forkhead box O1A (rhabdomyosarcoma)4110.2560.3691Yes
8RGS5RGS5
Entrez,  Source
regulator of G-protein signalling 55130.2240.3853Yes
9VCAM1VCAM1
Entrez,  Source
vascular cell adhesion molecule 15160.2230.4090Yes
10AQP7AQP7
Entrez,  Source
aquaporin 75480.2170.4297Yes
11IGFBP3IGFBP3
Entrez,  Source
insulin-like growth factor binding protein 35710.2120.4506Yes
12SGCESGCE
Entrez,  Source
sarcoglycan, epsilon6500.1970.4657Yes
13RHOBRHOB
Entrez,  Source
ras homolog gene family, member B7090.1840.4810Yes
14DIRC2DIRC2
Entrez,  Source
disrupted in renal carcinoma 27100.1840.5005Yes
15FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 17200.1820.5193Yes
16IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 37210.1820.5387Yes
17CCL7CCL7
Entrez,  Source
chemokine (C-C motif) ligand 78600.1610.5454Yes
18SULT1E1SULT1E1
Entrez,  Source
sulfotransferase family 1E, estrogen-preferring, member 19080.1560.5585Yes
19HEXAHEXA
Entrez,  Source
hexosaminidase A (alpha polypeptide)10070.1460.5666Yes
20CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)10410.1420.5793Yes
21NR4A1NR4A1
Entrez,  Source
nuclear receptor subfamily 4, group A, member 110430.1420.5943Yes
22TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 212410.1240.5927Yes
23NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)13490.1160.5971Yes
24PIRPIR
Entrez,  Source
pirin (iron-binding nuclear protein)14020.1130.6052Yes
25BMP4BMP4
Entrez,  Source
bone morphogenetic protein 415060.1080.6089Yes
26FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 115320.1060.6183Yes
27TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 127690.0610.5317No
28SDC4SDC4
Entrez,  Source
syndecan 4 (amphiglycan, ryudocan)33850.0450.4902No
29CEACAM1CEACAM1
Entrez,  Source
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)34190.0450.4925No
30KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)35670.0410.4858No
31ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor36930.0390.4805No
32HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 140750.0310.4552No
33ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)43860.0260.4345No
34BMP6BMP6
Entrez,  Source
bone morphogenetic protein 644980.0230.4287No
35HEMGNHEMGN
Entrez,  Source
hemogen45840.0220.4246No
36GALNT1GALNT1
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)48130.0180.4093No
37SP3SP3
Entrez,  Source
Sp3 transcription factor49380.0160.4017No
38PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein51430.0120.3877No
39DYNLL1DYNLL1
Entrez,  Source
dynein, light chain, LC8-type 156730.0050.3483No
40MMP2MMP2
Entrez,  Source
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)57800.0030.3406No
41OXTROXTR
Entrez,  Source
oxytocin receptor6165-0.0020.3120No
42PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)6239-0.0040.3069No
43PVALBPVALB
Entrez,  Source
parvalbumin6278-0.0040.3044No
44ESR1ESR1
Entrez,  Source
estrogen receptor 16300-0.0050.3034No
45MMP10MMP10
Entrez,  Source
matrix metallopeptidase 10 (stromelysin 2)6646-0.0100.2784No
46GJA4GJA4
Entrez,  Source
gap junction protein, alpha 4, 37kDa (connexin 37)6909-0.0140.2601No
47HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 26935-0.0140.2597No
48NAGKNAGK
Entrez,  Source
N-acetylglucosamine kinase7266-0.0190.2369No
49ANGPT2ANGPT2
Entrez,  Source
angiopoietin 27458-0.0220.2248No
50UBDUBD
Entrez,  Source
ubiquitin D8096-0.0320.1803No
51EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 18124-0.0330.1817No
52VWFVWF
Entrez,  Source
von Willebrand factor8376-0.0370.1668No
53EMR1EMR1
Entrez,  Source
egf-like module containing, mucin-like, hormone receptor-like 18911-0.0460.1314No
54ISL1ISL1
Entrez,  Source
ISL1 transcription factor, LIM/homeodomain, (islet-1)9336-0.0530.1051No
55ADD2ADD2
Entrez,  Source
adducin 2 (beta)9424-0.0550.1044No
56NDUFA1NDUFA1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa9627-0.0580.0954No
57CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)9690-0.0600.0970No
58PRKCIPRKCI
Entrez,  Source
protein kinase C, iota10240-0.0710.0633No
59RANGAP1RANGAP1
Entrez,  Source
Ran GTPase activating protein 110603-0.0800.0445No
60HTR2BHTR2B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2B10954-0.0890.0276No
61GSTT1GSTT1
Entrez,  Source
glutathione S-transferase theta 111104-0.0930.0263No
62SLC6A8SLC6A8
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, creatine), member 811161-0.0950.0322No
63FAPFAP
Entrez,  Source
fibroblast activation protein, alpha11212-0.0960.0387No
64THY1THY1
Entrez,  Source
Thy-1 cell surface antigen11400-0.1020.0355No
65UNGUNG
Entrez,  Source
uracil-DNA glycosylase11765-0.1160.0203No
66RALARALA
Entrez,  Source
v-ral simian leukemia viral oncogene homolog A (ras related)12043-0.1280.0131No
67RBX1RBX1
Entrez,  Source
ring-box 112058-0.1290.0259No
68MRPL19MRPL19
Entrez,  Source
mitochondrial ribosomal protein L1912073-0.1300.0387No
69PIM1PIM1
Entrez,  Source
pim-1 oncogene12606-0.1640.0160No
70TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2312662-0.1690.0299No
71GGHGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)12902-0.2000.0332No
Table: GSEA details [plain text format]



Fig 2: VEGF_MMMEC_ALL_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VEGF_MMMEC_ALL_UP: Random ES distribution   
Gene set null distribution of ES for VEGF_MMMEC_ALL_UP