Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | WIELAND_HEPATITIS_B_INDUCED |
| Enrichment Score (ES) | -0.48060587 |
| Normalized Enrichment Score (NES) | -1.6841832 |
| Nominal p-value | 0.0045871558 |
| FDR q-value | 0.09183902 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 32 | 0.725 | 0.0704 | No |
| 2 | CD48 | CD48 Entrez, Source | CD48 molecule | 352 | 0.281 | 0.0746 | No |
| 3 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 398 | 0.260 | 0.0973 | No |
| 4 | HLA-DMB | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 503 | 0.226 | 0.1122 | No |
| 5 | TYROBP | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 586 | 0.208 | 0.1269 | No |
| 6 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 639 | 0.199 | 0.1430 | No |
| 7 | LPXN | LPXN Entrez, Source | leupaxin | 785 | 0.172 | 0.1494 | No |
| 8 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 810 | 0.168 | 0.1644 | No |
| 9 | IGSF6 | IGSF6 Entrez, Source | immunoglobulin superfamily, member 6 | 1187 | 0.129 | 0.1491 | No |
| 10 | SP110 | SP110 Entrez, Source | SP110 nuclear body protein | 1446 | 0.111 | 0.1408 | No |
| 11 | GZMK | GZMK Entrez, Source | granzyme K (granzyme 3; tryptase II) | 1600 | 0.103 | 0.1396 | No |
| 12 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 1774 | 0.094 | 0.1360 | No |
| 13 | CD53 | CD53 Entrez, Source | CD53 molecule | 2501 | 0.068 | 0.0882 | No |
| 14 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 2746 | 0.061 | 0.0760 | No |
| 15 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 2806 | 0.060 | 0.0776 | No |
| 16 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 2872 | 0.058 | 0.0785 | No |
| 17 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 2981 | 0.055 | 0.0759 | No |
| 18 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 3017 | 0.054 | 0.0787 | No |
| 19 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 3294 | 0.047 | 0.0627 | No |
| 20 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 3732 | 0.038 | 0.0336 | No |
| 21 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 4301 | 0.027 | -0.0064 | No |
| 22 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 5086 | 0.014 | -0.0641 | No |
| 23 | IL10RA | IL10RA Entrez, Source | interleukin 10 receptor, alpha | 5276 | 0.011 | -0.0772 | No |
| 24 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 5682 | 0.005 | -0.1073 | No |
| 25 | B2M | B2M Entrez, Source | beta-2-microglobulin | 5795 | 0.003 | -0.1154 | No |
| 26 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5981 | 0.000 | -0.1293 | No |
| 27 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 6572 | -0.009 | -0.1729 | No |
| 28 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 6782 | -0.012 | -0.1874 | No |
| 29 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 7555 | -0.023 | -0.2432 | No |
| 30 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 7609 | -0.024 | -0.2447 | No |
| 31 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 8911 | -0.046 | -0.3381 | No |
| 32 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 8913 | -0.046 | -0.3335 | No |
| 33 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 9192 | -0.050 | -0.3494 | No |
| 34 | CTSC | CTSC Entrez, Source | cathepsin C | 9429 | -0.055 | -0.3617 | No |
| 35 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 9903 | -0.064 | -0.3908 | No |
| 36 | CD38 | CD38 Entrez, Source | CD38 molecule | 9966 | -0.066 | -0.3889 | No |
| 37 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 10004 | -0.066 | -0.3850 | No |
| 38 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 10414 | -0.075 | -0.4083 | No |
| 39 | CTSB | CTSB Entrez, Source | cathepsin B | 10843 | -0.086 | -0.4318 | No |
| 40 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 10892 | -0.088 | -0.4266 | No |
| 41 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 11445 | -0.104 | -0.4577 | No |
| 42 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 11710 | -0.114 | -0.4662 | No |
| 43 | CD3D | CD3D Entrez, Source | CD3d molecule, delta (CD3-TCR complex) | 11751 | -0.115 | -0.4576 | No |
| 44 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 12057 | -0.129 | -0.4676 | Yes |
| 45 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12217 | -0.137 | -0.4658 | Yes |
| 46 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 12296 | -0.142 | -0.4574 | Yes |
| 47 | GIMAP5 | GIMAP5 Entrez, Source | GTPase, IMAP family member 5 | 12589 | -0.162 | -0.4631 | Yes |
| 48 | CD68 | CD68 Entrez, Source | CD68 molecule | 12657 | -0.169 | -0.4512 | Yes |
| 49 | AURKA | AURKA Entrez, Source | aurora kinase A | 12673 | -0.170 | -0.4352 | Yes |
| 50 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12736 | -0.177 | -0.4221 | Yes |
| 51 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12799 | -0.185 | -0.4082 | Yes |
| 52 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 12940 | -0.207 | -0.3980 | Yes |
| 53 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 12987 | -0.216 | -0.3798 | Yes |
| 54 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 13061 | -0.237 | -0.3614 | Yes |
| 55 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.3417 | Yes |
| 56 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13301 | -0.450 | -0.3037 | Yes |
| 57 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13325 | -0.617 | -0.2434 | Yes |
| 58 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 13330 | -0.714 | -0.1720 | Yes |
| 59 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13335 | -0.851 | -0.0869 | Yes |
| 60 | CD5L | CD5L Entrez, Source | CD5 molecule-like | 13336 | -0.870 | 0.0005 | Yes |
