Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | AGED_MOUSE_CORTEX_UP |
| Enrichment Score (ES) | 0.62127876 |
| Normalized Enrichment Score (NES) | 1.8477551 |
| Nominal p-value | 0.0018621974 |
| FDR q-value | 0.02390193 |
| FWER p-Value | 0.864 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 6 | 0.953 | 0.2560 | Yes |
| 2 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 56 | 0.562 | 0.4034 | Yes |
| 3 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 130 | 0.390 | 0.5029 | Yes |
| 4 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 406 | 0.208 | 0.5382 | Yes |
| 5 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 460 | 0.193 | 0.5861 | Yes |
| 6 | CPE | CPE Entrez, Source | carboxypeptidase E | 589 | 0.167 | 0.6213 | Yes |
| 7 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1045 | 0.118 | 0.6188 | No |
| 8 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 1688 | 0.085 | 0.5935 | No |
| 9 | SOS2 | SOS2 Entrez, Source | son of sevenless homolog 2 (Drosophila) | 2013 | 0.073 | 0.5888 | No |
| 10 | BCAP29 | BCAP29 Entrez, Source | B-cell receptor-associated protein 29 | 3213 | 0.044 | 0.5107 | No |
| 11 | RASGRF1 | RASGRF1 Entrez, Source | Ras protein-specific guanine nucleotide-releasing factor 1 | 4564 | 0.022 | 0.4150 | No |
| 12 | ACTB | ACTB Entrez, Source | actin, beta | 4714 | 0.019 | 0.4091 | No |
| 13 | EPHA7 | EPHA7 Entrez, Source | EPH receptor A7 | 5489 | 0.009 | 0.3532 | No |
| 14 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 6148 | 0.000 | 0.3038 | No |
| 15 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6398 | -0.003 | 0.2859 | No |
| 16 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 6870 | -0.009 | 0.2530 | No |
| 17 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 6950 | -0.010 | 0.2498 | No |
| 18 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 7287 | -0.014 | 0.2283 | No |
| 19 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 7545 | -0.017 | 0.2137 | No |
| 20 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 8130 | -0.026 | 0.1766 | No |
| 21 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 9787 | -0.050 | 0.0657 | No |
| 22 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 10069 | -0.055 | 0.0593 | No |
| 23 | PREP | PREP Entrez, Source | prolyl endopeptidase | 10771 | -0.068 | 0.0249 | No |
| 24 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 10816 | -0.069 | 0.0401 | No |
| 25 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10990 | -0.073 | 0.0467 | No |
| 26 | RDX | RDX Entrez, Source | radixin | 11042 | -0.074 | 0.0628 | No |
| 27 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 11160 | -0.077 | 0.0748 | No |
| 28 | C1QBP | C1QBP Entrez, Source | complement component 1, q subcomponent binding protein | 11506 | -0.086 | 0.0721 | No |
| 29 | EIF1 | EIF1 Entrez, Source | eukaryotic translation initiation factor 1 | 11741 | -0.093 | 0.0797 | No |
| 30 | DCK | DCK Entrez, Source | deoxycytidine kinase | 12784 | -0.151 | 0.0419 | No |
