Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ASTON_DEPRESSION_UP |
| Enrichment Score (ES) | 0.6617917 |
| Normalized Enrichment Score (NES) | 1.7881954 |
| Nominal p-value | 0.0018552876 |
| FDR q-value | 0.033426344 |
| FWER p-Value | 0.978 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 5 | 0.972 | 0.3582 | Yes |
| 2 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 372 | 0.219 | 0.4116 | Yes |
| 3 | JUN | JUN Entrez, Source | jun oncogene | 458 | 0.194 | 0.4767 | Yes |
| 4 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 742 | 0.145 | 0.5091 | Yes |
| 5 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 920 | 0.127 | 0.5427 | Yes |
| 6 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 1099 | 0.115 | 0.5717 | Yes |
| 7 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 1170 | 0.111 | 0.6074 | Yes |
| 8 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1360 | 0.101 | 0.6303 | Yes |
| 9 | GSTM3 | GSTM3 Entrez, Source | glutathione S-transferase M3 (brain) | 1419 | 0.097 | 0.6618 | Yes |
| 10 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 2222 | 0.067 | 0.6261 | No |
| 11 | TTR | TTR Entrez, Source | transthyretin (prealbumin, amyloidosis type I) | 2525 | 0.059 | 0.6253 | No |
| 12 | OSBPL2 | OSBPL2 Entrez, Source | oxysterol binding protein-like 2 | 3359 | 0.041 | 0.5780 | No |
| 13 | PTHR1 | PTHR1 Entrez, Source | parathyroid hormone receptor 1 | 3437 | 0.040 | 0.5869 | No |
| 14 | DLGAP1 | DLGAP1 Entrez, Source | discs, large (Drosophila) homolog-associated protein 1 | 4562 | 0.022 | 0.5105 | No |
| 15 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 5410 | 0.010 | 0.4504 | No |
| 16 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 5461 | 0.009 | 0.4500 | No |
| 17 | CCKBR | CCKBR Entrez, Source | cholecystokinin B receptor | 6826 | -0.008 | 0.3507 | No |
| 18 | RAB2 | RAB2 Entrez, Source | RAB2, member RAS oncogene family | 9314 | -0.042 | 0.1795 | No |
| 19 | APC | APC Entrez, Source | adenomatosis polyposis coli | 9645 | -0.048 | 0.1723 | No |
| 20 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 10344 | -0.059 | 0.1417 | No |
| 21 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 13154 | -0.226 | 0.0141 | No |
