Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BASSO_GERMINAL_CENTER_CD40_UP |
| Enrichment Score (ES) | 0.53096986 |
| Normalized Enrichment Score (NES) | 1.7597777 |
| Nominal p-value | 0.0018518518 |
| FDR q-value | 0.038846258 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 27 | 0.668 | 0.0950 | Yes |
| 2 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 40 | 0.620 | 0.1843 | Yes |
| 3 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 47 | 0.597 | 0.2705 | Yes |
| 4 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 140 | 0.372 | 0.3177 | Yes |
| 5 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 183 | 0.333 | 0.3630 | Yes |
| 6 | PTK2B | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 279 | 0.262 | 0.3939 | Yes |
| 7 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 427 | 0.202 | 0.4121 | Yes |
| 8 | CD40 | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 467 | 0.191 | 0.4369 | Yes |
| 9 | IER3 | IER3 Entrez, Source | immediate early response 3 | 598 | 0.165 | 0.4510 | Yes |
| 10 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 866 | 0.132 | 0.4502 | Yes |
| 11 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.4675 | Yes |
| 12 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1014 | 0.121 | 0.4756 | Yes |
| 13 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1045 | 0.118 | 0.4905 | Yes |
| 14 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 1208 | 0.109 | 0.4942 | Yes |
| 15 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 1231 | 0.108 | 0.5082 | Yes |
| 16 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.5195 | Yes |
| 17 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 1350 | 0.101 | 0.5294 | Yes |
| 18 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 1510 | 0.093 | 0.5310 | Yes |
| 19 | TRIP10 | TRIP10 Entrez, Source | thyroid hormone receptor interactor 10 | 1763 | 0.082 | 0.5239 | No |
| 20 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 2324 | 0.064 | 0.4910 | No |
| 21 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 2770 | 0.053 | 0.4653 | No |
| 22 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 2955 | 0.050 | 0.4587 | No |
| 23 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 3045 | 0.048 | 0.4589 | No |
| 24 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 3143 | 0.046 | 0.4582 | No |
| 25 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 3468 | 0.039 | 0.4395 | No |
| 26 | SNF1LK | SNF1LK Entrez, Source | SNF1-like kinase | 3570 | 0.037 | 0.4373 | No |
| 27 | NEF3 | NEF3 Entrez, Source | neurofilament 3 (150kDa medium) | 3572 | 0.037 | 0.4427 | No |
| 28 | SYNGR2 | SYNGR2 Entrez, Source | synaptogyrin 2 | 3612 | 0.037 | 0.4451 | No |
| 29 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 3654 | 0.036 | 0.4472 | No |
| 30 | TNFSF9 | TNFSF9 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 9 | 4248 | 0.026 | 0.4064 | No |
| 31 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 4764 | 0.019 | 0.3703 | No |
| 32 | PLEK | PLEK Entrez, Source | pleckstrin | 4826 | 0.018 | 0.3683 | No |
| 33 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 4863 | 0.017 | 0.3682 | No |
| 34 | PHACTR1 | PHACTR1 Entrez, Source | phosphatase and actin regulator 1 | 4988 | 0.015 | 0.3611 | No |
| 35 | LTA | LTA Entrez, Source | lymphotoxin alpha (TNF superfamily, member 1) | 5175 | 0.013 | 0.3489 | No |
| 36 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 5665 | 0.006 | 0.3130 | No |
| 37 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 6191 | -0.000 | 0.2736 | No |
| 38 | ELL2 | ELL2 Entrez, Source | elongation factor, RNA polymerase II, 2 | 6213 | -0.001 | 0.2721 | No |
| 39 | STK10 | STK10 Entrez, Source | serine/threonine kinase 10 | 6444 | -0.004 | 0.2553 | No |
| 40 | EHD1 | EHD1 Entrez, Source | EH-domain containing 1 | 6660 | -0.007 | 0.2401 | No |
| 41 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 6719 | -0.007 | 0.2368 | No |
| 42 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 7239 | -0.014 | 0.1997 | No |
| 43 | HTR3A | HTR3A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 3A | 7483 | -0.016 | 0.1838 | No |
| 44 | CCL22 | CCL22 Entrez, Source | chemokine (C-C motif) ligand 22 | 7969 | -0.023 | 0.1506 | No |
| 45 | UNC119 | UNC119 Entrez, Source | unc-119 homolog (C. elegans) | 8442 | -0.030 | 0.1194 | No |
| 46 | DTX2 | DTX2 Entrez, Source | deltex homolog 2 (Drosophila) | 8976 | -0.037 | 0.0847 | No |
| 47 | TCEB3 | TCEB3 Entrez, Source | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | 9185 | -0.040 | 0.0749 | No |
| 48 | SH2B3 | SH2B3 Entrez, Source | SH2B adaptor protein 3 | 9274 | -0.041 | 0.0743 | No |
| 49 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 10190 | -0.057 | 0.0136 | No |
| 50 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.0225 | No |
| 51 | SNN | SNN Entrez, Source | stannin | 11331 | -0.082 | -0.0502 | No |
| 52 | KCNN4 | KCNN4 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 11462 | -0.085 | -0.0476 | No |
| 53 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 11635 | -0.090 | -0.0475 | No |
| 54 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11920 | -0.100 | -0.0544 | No |
| 55 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12283 | -0.115 | -0.0649 | No |
| 56 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12596 | -0.134 | -0.0688 | No |
| 57 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 12743 | -0.146 | -0.0587 | No |
| 58 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 12996 | -0.183 | -0.0510 | No |
| 59 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13324 | -0.530 | 0.0014 | No |
