Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BASSO_HCL_DIFF |
| Enrichment Score (ES) | 0.6046394 |
| Normalized Enrichment Score (NES) | 1.9269816 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011885933 |
| FWER p-Value | 0.484 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.1366 | Yes |
| 2 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 44 | 0.606 | 0.2362 | Yes |
| 3 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 46 | 0.599 | 0.3371 | Yes |
| 4 | TACC1 | TACC1 Entrez, Source | transforming, acidic coiled-coil containing protein 1 | 53 | 0.575 | 0.4335 | Yes |
| 5 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 73 | 0.484 | 0.5137 | Yes |
| 6 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 251 | 0.281 | 0.5477 | Yes |
| 7 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.5527 | Yes |
| 8 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 633 | 0.160 | 0.5748 | Yes |
| 9 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 663 | 0.156 | 0.5989 | Yes |
| 10 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 881 | 0.131 | 0.6046 | Yes |
| 11 | IL3RA | IL3RA Entrez, Source | interleukin 3 receptor, alpha (low affinity) | 1257 | 0.107 | 0.5944 | No |
| 12 | MYF6 | MYF6 Entrez, Source | myogenic factor 6 (herculin) | 1536 | 0.092 | 0.5890 | No |
| 13 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 1871 | 0.078 | 0.5770 | No |
| 14 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 2152 | 0.069 | 0.5674 | No |
| 15 | PDE4DIP | PDE4DIP Entrez, Source | phosphodiesterase 4D interacting protein (myomegalin) | 2158 | 0.068 | 0.5786 | No |
| 16 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 2178 | 0.068 | 0.5886 | No |
| 17 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 2366 | 0.063 | 0.5851 | No |
| 18 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 2421 | 0.061 | 0.5914 | No |
| 19 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 2687 | 0.055 | 0.5808 | No |
| 20 | HBB | HBB Entrez, Source | hemoglobin, beta | 2720 | 0.055 | 0.5876 | No |
| 21 | GAS7 | GAS7 Entrez, Source | growth arrest-specific 7 | 3024 | 0.048 | 0.5729 | No |
| 22 | VAMP3 | VAMP3 Entrez, Source | vesicle-associated membrane protein 3 (cellubrevin) | 3135 | 0.046 | 0.5723 | No |
| 23 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 3256 | 0.044 | 0.5706 | No |
| 24 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 4047 | 0.030 | 0.5162 | No |
| 25 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 4666 | 0.020 | 0.4731 | No |
| 26 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 4764 | 0.019 | 0.4689 | No |
| 27 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 4794 | 0.018 | 0.4698 | No |
| 28 | B2M | B2M Entrez, Source | beta-2-microglobulin | 4992 | 0.015 | 0.4576 | No |
| 29 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 5027 | 0.015 | 0.4576 | No |
| 30 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 5138 | 0.013 | 0.4515 | No |
| 31 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 5148 | 0.013 | 0.4531 | No |
| 32 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 5527 | 0.008 | 0.4260 | No |
| 33 | CD63 | CD63 Entrez, Source | CD63 molecule | 6300 | -0.002 | 0.3682 | No |
| 34 | SIX3 | SIX3 Entrez, Source | sine oculis homeobox homolog 3 (Drosophila) | 6502 | -0.004 | 0.3539 | No |
| 35 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 7176 | -0.013 | 0.3054 | No |
| 36 | SDC3 | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 7719 | -0.020 | 0.2679 | No |
| 37 | ENG | ENG Entrez, Source | endoglin (Osler-Rendu-Weber syndrome 1) | 8089 | -0.025 | 0.2444 | No |
| 38 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 8524 | -0.031 | 0.2170 | No |
| 39 | RTN2 | RTN2 Entrez, Source | reticulon 2 | 9234 | -0.041 | 0.1705 | No |
| 40 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 9958 | -0.053 | 0.1250 | No |
| 41 | TBKBP1 | TBKBP1 Entrez, Source | TBK1 binding protein 1 | 10053 | -0.054 | 0.1271 | No |
| 42 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 10156 | -0.056 | 0.1289 | No |
| 43 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 10721 | -0.067 | 0.0977 | No |
| 44 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 10807 | -0.069 | 0.1028 | No |
| 45 | PTPRM | PTPRM Entrez, Source | protein tyrosine phosphatase, receptor type, M | 10978 | -0.073 | 0.1023 | No |
| 46 | RCBTB2 | RCBTB2 Entrez, Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 13039 | -0.195 | -0.0197 | No |
| 47 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 13197 | -0.252 | 0.0109 | No |
