Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BLEO_HUMAN_LYMPH_HIGH_24HRS_UP |
| Enrichment Score (ES) | 0.5680228 |
| Normalized Enrichment Score (NES) | 1.8859324 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.018365253 |
| FWER p-Value | 0.709 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 11 | 0.815 | 0.1170 | Yes |
| 2 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 58 | 0.559 | 0.1943 | Yes |
| 3 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 76 | 0.477 | 0.2620 | Yes |
| 4 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 126 | 0.391 | 0.3148 | Yes |
| 5 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 160 | 0.355 | 0.3636 | Yes |
| 6 | LPXN | LPXN Entrez, Source | leupaxin | 317 | 0.240 | 0.3866 | Yes |
| 7 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 326 | 0.238 | 0.4203 | Yes |
| 8 | CD40 | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 467 | 0.191 | 0.4373 | Yes |
| 9 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 722 | 0.148 | 0.4396 | Yes |
| 10 | TAX1BP3 | TAX1BP3 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 791 | 0.140 | 0.4548 | Yes |
| 11 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.4664 | Yes |
| 12 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 979 | 0.123 | 0.4774 | Yes |
| 13 | ENC1 | ENC1 Entrez, Source | ectodermal-neural cortex (with BTB-like domain) | 1029 | 0.119 | 0.4908 | Yes |
| 14 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 1050 | 0.118 | 0.5063 | Yes |
| 15 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 1206 | 0.109 | 0.5104 | Yes |
| 16 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 1208 | 0.109 | 0.5261 | Yes |
| 17 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.5356 | Yes |
| 18 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 1439 | 0.096 | 0.5380 | Yes |
| 19 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 1454 | 0.096 | 0.5508 | Yes |
| 20 | PKIG | PKIG Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 1533 | 0.092 | 0.5583 | Yes |
| 21 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 1688 | 0.085 | 0.5590 | Yes |
| 22 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 1729 | 0.083 | 0.5680 | Yes |
| 23 | PTP4A1 | PTP4A1 Entrez, Source | protein tyrosine phosphatase type IVA, member 1 | 2184 | 0.068 | 0.5436 | No |
| 24 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2350 | 0.063 | 0.5404 | No |
| 25 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 2447 | 0.061 | 0.5419 | No |
| 26 | PRKAB1 | PRKAB1 Entrez, Source | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 2502 | 0.060 | 0.5465 | No |
| 27 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 2648 | 0.056 | 0.5437 | No |
| 28 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 2902 | 0.051 | 0.5320 | No |
| 29 | MRPL49 | MRPL49 Entrez, Source | mitochondrial ribosomal protein L49 | 3463 | 0.039 | 0.4955 | No |
| 30 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 3468 | 0.039 | 0.5009 | No |
| 31 | HCLS1 | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 3587 | 0.037 | 0.4973 | No |
| 32 | SMTN | SMTN Entrez, Source | smoothelin | 3924 | 0.031 | 0.4766 | No |
| 33 | TNFSF9 | TNFSF9 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 9 | 4248 | 0.026 | 0.4561 | No |
| 34 | PLEK | PLEK Entrez, Source | pleckstrin | 4826 | 0.018 | 0.4152 | No |
| 35 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 4863 | 0.017 | 0.4150 | No |
| 36 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 4892 | 0.017 | 0.4153 | No |
| 37 | LTA | LTA Entrez, Source | lymphotoxin alpha (TNF superfamily, member 1) | 5175 | 0.013 | 0.3960 | No |
| 38 | RUNX3 | RUNX3 Entrez, Source | runt-related transcription factor 3 | 5356 | 0.010 | 0.3839 | No |
| 39 | CTSH | CTSH Entrez, Source | cathepsin H | 5387 | 0.010 | 0.3831 | No |
| 40 | SH3BP5 | SH3BP5 Entrez, Source | SH3-domain binding protein 5 (BTK-associated) | 5605 | 0.007 | 0.3678 | No |
| 41 | RPS6KA1 | RPS6KA1 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 5670 | 0.006 | 0.3638 | No |
| 42 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5788 | 0.005 | 0.3557 | No |
| 43 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 5876 | 0.004 | 0.3496 | No |
| 44 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 6479 | -0.004 | 0.3049 | No |
| 45 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 6971 | -0.010 | 0.2694 | No |
| 46 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 7239 | -0.014 | 0.2513 | No |
| 47 | EI24 | EI24 Entrez, Source | etoposide induced 2.4 mRNA | 7443 | -0.016 | 0.2383 | No |
| 48 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 7976 | -0.023 | 0.2016 | No |
| 49 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 8130 | -0.026 | 0.1938 | No |
| 50 | WDR1 | WDR1 Entrez, Source | WD repeat domain 1 | 8188 | -0.026 | 0.1933 | No |
| 51 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 8408 | -0.029 | 0.1811 | No |
| 52 | PLXNB2 | PLXNB2 Entrez, Source | plexin B2 | 9773 | -0.050 | 0.0856 | No |
| 53 | CRYZ | CRYZ Entrez, Source | crystallin, zeta (quinone reductase) | 10382 | -0.060 | 0.0484 | No |
| 54 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 11436 | -0.085 | -0.0186 | No |
| 55 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 11477 | -0.086 | -0.0092 | No |
| 56 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12567 | -0.133 | -0.0720 | No |
| 57 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12570 | -0.133 | -0.0530 | No |
| 58 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12596 | -0.134 | -0.0355 | No |
| 59 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 12996 | -0.183 | -0.0390 | No |
| 60 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | -0.0136 | No |
| 61 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 13202 | -0.257 | 0.0105 | No |
