Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetBOQUEST_CD31PLUS_VS_CD31MINUS_DN
Enrichment Score (ES)0.5198921
Normalized Enrichment Score (NES)1.9937094
Nominal p-value0.0
FDR q-value0.0061888862
FWER p-Value0.232
Table: GSEA Results Summary



Fig 1: Enrichment plot: BOQUEST_CD31PLUS_VS_CD31MINUS_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 231.0460.0594Yes
2COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)150.7370.1006Yes
3BHLHB3BHLHB3
Entrez,  Source
basic helix-loop-helix domain containing, class B, 3230.6820.1389Yes
4COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2280.6680.1767Yes
5MGPMGP
Entrez,  Source
matrix Gla protein620.5330.2046Yes
6MRC2MRC2
Entrez,  Source
mannose receptor, C type 2720.4850.2316Yes
7OMDOMD
Entrez,  Source
osteomodulin790.4700.2579Yes
8LOXLOX
Entrez,  Source
lysyl oxidase820.4650.2843Yes
9SERPINE2SERPINE2
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 21040.4240.3069Yes
10TNFAIP6TNFAIP6
Entrez,  Source
tumor necrosis factor, alpha-induced protein 61170.4020.3289Yes
11PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein1190.4010.3517Yes
12FSTFST
Entrez,  Source
follistatin1320.3880.3729Yes
13CRYABCRYAB
Entrez,  Source
crystallin, alpha B1410.3710.3935Yes
14CFDCFD
Entrez,  Source
complement factor D (adipsin)3370.2340.3920Yes
15EMP3EMP3
Entrez,  Source
epithelial membrane protein 33580.2270.4035Yes
16GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)4170.2050.4107Yes
17F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)4180.2050.4224Yes
18S100A4S100A4
Entrez,  Source
S100 calcium binding protein A44500.1950.4312Yes
19COL6A2COL6A2
Entrez,  Source
collagen, type VI, alpha 24600.1930.4415Yes
20FEZ1FEZ1
Entrez,  Source
fasciculation and elongation protein zeta 1 (zygin I)4680.1900.4518Yes
21FBN1FBN1
Entrez,  Source
fibrillin 14830.1850.4613Yes
22SGCESGCE
Entrez,  Source
sarcoglycan, epsilon4840.1850.4719Yes
23IGFBP3IGFBP3
Entrez,  Source
insulin-like growth factor binding protein 35670.1700.4754Yes
24SCRN1SCRN1
Entrez,  Source
secernin 15680.1700.4851Yes
25TSPAN8TSPAN8
Entrez,  Source
tetraspanin 86590.1560.4872Yes
26COL1A1COL1A1
Entrez,  Source
collagen, type I, alpha 17380.1460.4895Yes
27PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 17420.1450.4976Yes
28PLA2G4APLA2G4A
Entrez,  Source
phospholipase A2, group IVA (cytosolic, calcium-dependent)8120.1390.5003Yes
29TWIST1TWIST1
Entrez,  Source
twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)9780.1230.4948Yes
30LIFLIF
Entrez,  Source
leukemia inhibitory factor (cholinergic differentiation factor)10370.1180.4972Yes
31BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 110500.1180.5030Yes
32TMEM176BTMEM176B
Entrez,  Source
transmembrane protein 176B10870.1160.5068Yes
33PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D10880.1160.5134Yes
34CYBRD1CYBRD1
Entrez,  Source
cytochrome b reductase 111780.1110.5130Yes
35ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A111830.1100.5189Yes
36HNMTHNMT
Entrez,  Source
histamine N-methyltransferase13780.1000.5099Yes
37COL5A1COL5A1
Entrez,  Source
collagen, type V, alpha 114040.0980.5136Yes
38GSTM3GSTM3
Entrez,  Source
glutathione S-transferase M3 (brain)14190.0970.5181Yes
39EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 214680.0950.5199Yes
40PLA2G2APLA2G2A
Entrez,  Source
phospholipase A2, group IIA (platelets, synovial fluid)15780.0900.5168No
41APODAPOD
Entrez,  Source
apolipoprotein D16530.0870.5161No
42ACOX2ACOX2
Entrez,  Source
acyl-Coenzyme A oxidase 2, branched chain17110.0840.5166No
43CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta17740.0820.5165No
44OSR2OSR2
Entrez,  Source
odd-skipped related 2 (Drosophila)19010.0770.5113No
45LTBP2LTBP2
Entrez,  Source
latent transforming growth factor beta binding protein 219800.0740.5096No
46MFAP4MFAP4
Entrez,  Source
microfibrillar-associated protein 421150.0690.5034No
47PDE4DIPPDE4DIP
Entrez,  Source
phosphodiesterase 4D interacting protein (myomegalin)21580.0680.5041No
48NOVA1NOVA1
Entrez,  Source
neuro-oncological ventral antigen 121780.0680.5065No
49SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 523060.0640.5006No
50APOEAPOE
Entrez,  Source
apolipoprotein E23450.0630.5013No
51CHRDL1CHRDL1
Entrez,  Source
chordin-like 124160.0620.4995No
52GPC3GPC3
Entrez,  Source
glypican 325140.0590.4956No
53GPC4GPC4
Entrez,  Source
glypican 425530.0580.4960No
54CRABP2CRABP2
Entrez,  Source
cellular retinoic acid binding protein 225660.0580.4984No
55SLIT2SLIT2
Entrez,  Source
slit homolog 2 (Drosophila)28850.0510.4772No
56WISP2WISP2
Entrez,  Source
WNT1 inducible signaling pathway protein 229010.0510.4790No
57CDH11CDH11
Entrez,  Source
cadherin 11, type 2, OB-cadherin (osteoblast)29610.0500.4773No
58GAS7GAS7
Entrez,  Source
growth arrest-specific 730240.0480.4754No
59DCNDCN
Entrez,  Source
decorin30290.0480.4778No
60CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)31430.0460.4718No
61TIMP1TIMP1
Entrez,  Source
TIMP metallopeptidase inhibitor 132560.0440.4658No
62KCND2KCND2
Entrez,  Source
potassium voltage-gated channel, Shal-related subfamily, member 232720.0430.4671No
63GSTM5GSTM5
Entrez,  Source
glutathione S-transferase M533420.0420.4643No
64DZIP1DZIP1
Entrez,  Source
DAZ interacting protein 136420.0360.4437No
65HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 137900.0340.4344No
66DCXDCX
Entrez,  Source
doublecortex; lissencephaly, X-linked (doublecortin)38370.0330.4328No
67PTGFRPTGFR
Entrez,  Source
prostaglandin F receptor (FP)38850.0320.4311No
68GFPT2GFPT2
Entrez,  Source
glutamine-fructose-6-phosphate transaminase 239120.0320.4309No
69MMP2MMP2
Entrez,  Source
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)39780.0310.4277No
70FXYD1FXYD1
Entrez,  Source
FXYD domain containing ion transport regulator 1 (phospholemman)43780.0240.3989No
71INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)45960.0210.3836No
72LUMLUM
Entrez,  Source
lumican47280.0190.3748No
73FIGFFIGF
Entrez,  Source
c-fos induced growth factor (vascular endothelial growth factor D)48550.0170.3662No
74MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle48990.0170.3639No
75COL16A1COL16A1
Entrez,  Source
collagen, type XVI, alpha 150510.0150.3533No
76LSP1LSP1
Entrez,  Source
lymphocyte-specific protein 151150.0140.3493No
77PRRX1PRRX1
Entrez,  Source
paired related homeobox 151890.0130.3445No
78CTSKCTSK
Entrez,  Source
cathepsin K (pycnodysostosis)54160.0100.3279No
79CUGBP2CUGBP2
Entrez,  Source
CUG triplet repeat, RNA binding protein 254610.0090.3251No
80CAPN6CAPN6
Entrez,  Source
calpain 654800.0090.3242No
81SFRP4SFRP4
Entrez,  Source
secreted frizzled-related protein 454840.0090.3245No
82BMPR1ABMPR1A
Entrez,  Source
bone morphogenetic protein receptor, type IA56410.0060.3130No
83AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase56490.0060.3128No
84TMED3TMED3
Entrez,  Source
transmembrane emp24 protein transport domain containing 357970.0050.3020No
85FGF7FGF7
Entrez,  Source
fibroblast growth factor 7 (keratinocyte growth factor)58750.0040.2963No
86MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response58850.0040.2958No
87PCOLCEPCOLCE
Entrez,  Source
procollagen C-endopeptidase enhancer6215-0.0010.2709No
88CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)6239-0.0010.2693No
89IGFBP6IGFBP6
Entrez,  Source
insulin-like growth factor binding protein 66428-0.0040.2552No
90SRPXSRPX
Entrez,  Source
sushi-repeat-containing protein, X-linked6552-0.0050.2462No
91SPON2SPON2
Entrez,  Source
spondin 2, extracellular matrix protein6569-0.0050.2453No
92PDLIM3PDLIM3
Entrez,  Source
PDZ and LIM domain 36654-0.0060.2393No
93CXCL14CXCL14
Entrez,  Source
chemokine (C-X-C motif) ligand 146682-0.0070.2376No
94LRRC17LRRC17
Entrez,  Source
leucine rich repeat containing 176786-0.0080.2303No
95PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)6790-0.0080.2305No
96FBLN5FBLN5
Entrez,  Source
fibulin 56975-0.0100.2171No
97NPY1RNPY1R
Entrez,  Source
neuropeptide Y receptor Y16976-0.0100.2177No
98SPOCK1SPOCK1
Entrez,  Source
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 17173-0.0130.2036No
99DCAMKL1DCAMKL1
Entrez,  Source
doublecortin and CaM kinase-like 17197-0.0130.2026No
100NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 27314-0.0140.1946No
101PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide7343-0.0150.1933No
102ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)7439-0.0160.1870No
103DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 27491-0.0170.1841No
104KCNK1KCNK1
Entrez,  Source
potassium channel, subfamily K, member 17542-0.0170.1813No
105SLIT3SLIT3
Entrez,  Source
slit homolog 3 (Drosophila)7586-0.0180.1791No
106MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)7620-0.0180.1776No
107IRS1IRS1
Entrez,  Source
insulin receptor substrate 18456-0.0300.1160No
108PDGFRLPDGFRL
Entrez,  Source
platelet-derived growth factor receptor-like8576-0.0320.1088No
109CFHCFH
Entrez,  Source
complement factor H8669-0.0330.1037No
110SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 18926-0.0360.0864No
111CD302CD302
Entrez,  Source
CD302 molecule8988-0.0370.0839No
112ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)8993-0.0370.0858No
113PTGISPTGIS
Entrez,  Source
prostaglandin I2 (prostacyclin) synthase9012-0.0380.0865No
114ROBO1ROBO1
Entrez,  Source
roundabout, axon guidance receptor, homolog 1 (Drosophila)9015-0.0380.0885No
115HSPB8HSPB8
Entrez,  Source
heat shock 22kDa protein 89051-0.0380.0881No
116ANGPT1ANGPT1
Entrez,  Source
angiopoietin 19136-0.0390.0839No
117THBS2THBS2
Entrez,  Source
thrombospondin 29270-0.0410.0762No
118RNASE4RNASE4
Entrez,  Source
ribonuclease, RNase A family, 49382-0.0430.0703No
119ATP1A2ATP1A2
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide9475-0.0450.0658No
120MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)9601-0.0470.0590No
121FMODFMOD
Entrez,  Source
fibromodulin9724-0.0490.0526No
122COLEC12COLEC12
Entrez,  Source
collectin sub-family member 129996-0.0530.0351No
123IGF1IGF1
Entrez,  Source
insulin-like growth factor 1 (somatomedin C)10373-0.0600.0100No
124CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)10417-0.0610.0102No
125GRIA3GRIA3
Entrez,  Source
glutamate receptor, ionotrophic, AMPA 310426-0.0610.0130No
126WNT5AWNT5A
Entrez,  Source
wingless-type MMTV integration site family, member 5A10507-0.0620.0105No
127LRP1LRP1
Entrez,  Source
low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)10559-0.0630.0103No
128NET1NET1
Entrez,  Source
neuroepithelial cell transforming gene 110614-0.0650.0098No
129PLNPLN
Entrez,  Source
phospholamban10671-0.0660.0093No
130GDF10GDF10
Entrez,  Source
growth differentiation factor 1010910-0.071-0.0047No
131PDGFDPDGFD
Entrez,  Source
platelet derived growth factor D10958-0.072-0.0041No
132SLC22A3SLC22A3
Entrez,  Source
solute carrier family 22 (extraneuronal monoamine transporter), member 311185-0.078-0.0168No
133EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)11286-0.081-0.0198No
134NT5ENT5E
Entrez,  Source
5'-nucleotidase, ecto (CD73)11299-0.081-0.0160No
135SHOX2SHOX2
Entrez,  Source
short stature homeobox 211349-0.083-0.0150No
136SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)11419-0.084-0.0154No
137CFBCFB
Entrez,  Source
complement factor B11731-0.093-0.0337No
138MBPMBP
Entrez,  Source
myelin basic protein11862-0.098-0.0380No
139EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 112182-0.111-0.0559No
140F10F10
Entrez,  Source
coagulation factor X12278-0.115-0.0565No
141C1ORF24C1ORF24
Entrez,  Source
chromosome 1 open reading frame 2412389-0.121-0.0580No
142OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)12390-0.121-0.0511No
143SOX9SOX9
Entrez,  Source
SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)12395-0.121-0.0445No
144GPNMBGPNMB
Entrez,  Source
glycoprotein (transmembrane) nmb12406-0.122-0.0383No
145CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I12594-0.134-0.0449No
146FAPFAP
Entrez,  Source
fibroblast activation protein, alpha12774-0.149-0.0499No
147UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase12882-0.162-0.0488No
148CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)12892-0.163-0.0401No
149C6C6
Entrez,  Source
complement component 612932-0.169-0.0334No
150NOTCH2NOTCH2
Entrez,  Source
Notch homolog 2 (Drosophila)13133-0.220-0.0361No
151AOX1AOX1
Entrez,  Source
aldehyde oxidase 113183-0.242-0.0260No
152FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 113185-0.244-0.0121No
153CES1CES1
Entrez,  Source
carboxylesterase 1 (monocyte/macrophage serine esterase 1)13305-0.4200.0028No
Table: GSEA details [plain text format]



Fig 2: BOQUEST_CD31PLUS_VS_CD31MINUS_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BOQUEST_CD31PLUS_VS_CD31MINUS_DN: Random ES distribution   
Gene set null distribution of ES for BOQUEST_CD31PLUS_VS_CD31MINUS_DN