Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | CANTHARIDIN_DN |
| Enrichment Score (ES) | -0.43680567 |
| Normalized Enrichment Score (NES) | -1.3786513 |
| Nominal p-value | 0.08811475 |
| FDR q-value | 0.48518738 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 139 | 0.373 | 0.1403 | No |
| 2 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1828 | 0.079 | 0.0455 | No |
| 3 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 3325 | 0.042 | -0.0499 | No |
| 4 | UQCRH | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 3467 | 0.039 | -0.0446 | No |
| 5 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 3505 | 0.039 | -0.0318 | No |
| 6 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 4457 | 0.023 | -0.0940 | No |
| 7 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 5246 | 0.012 | -0.1484 | No |
| 8 | ATP5G3 | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 5742 | 0.005 | -0.1835 | No |
| 9 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | -0.3237 | No |
| 10 | FARSLB | FARSLB Entrez, Source | phenylalanine-tRNA synthetase-like, beta subunit | 8478 | -0.031 | -0.3686 | No |
| 11 | HNRPC | HNRPC Entrez, Source | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 9106 | -0.039 | -0.3999 | No |
| 12 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 9276 | -0.041 | -0.3959 | No |
| 13 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 9822 | -0.051 | -0.4163 | Yes |
| 14 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 10090 | -0.055 | -0.4142 | Yes |
| 15 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 10227 | -0.057 | -0.4013 | Yes |
| 16 | TRAP1 | TRAP1 Entrez, Source | TNF receptor-associated protein 1 | 10316 | -0.059 | -0.3841 | Yes |
| 17 | ABCA3 | ABCA3 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 3 | 10729 | -0.067 | -0.3881 | Yes |
| 18 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 10874 | -0.070 | -0.3704 | Yes |
| 19 | EIF3S9 | EIF3S9 Entrez, Source | eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa | 10891 | -0.071 | -0.3431 | Yes |
| 20 | EEF1D | EEF1D Entrez, Source | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 11131 | -0.077 | -0.3301 | Yes |
| 21 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 11282 | -0.081 | -0.3087 | Yes |
| 22 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 12039 | -0.104 | -0.3232 | Yes |
| 23 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 12067 | -0.106 | -0.2825 | Yes |
| 24 | SLK | SLK Entrez, Source | STE20-like kinase (yeast) | 12099 | -0.107 | -0.2415 | Yes |
| 25 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12141 | -0.109 | -0.2005 | Yes |
| 26 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.1583 | Yes |
| 27 | GTF3A | GTF3A Entrez, Source | general transcription factor IIIA | 12256 | -0.114 | -0.1182 | Yes |
| 28 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 12683 | -0.140 | -0.0934 | Yes |
| 29 | ABCC4 | ABCC4 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 12968 | -0.176 | -0.0437 | Yes |
| 30 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 12975 | -0.177 | 0.0276 | Yes |
