Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_72h
GeneSetCELLULAR_BIOSYNTHETIC_PROCESS
Enrichment Score (ES)-0.29960588
Normalized Enrichment Score (NES)-1.296648
Nominal p-value0.025396826
FDR q-value0.5689108
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: CELLULAR_BIOSYNTHETIC_PROCESS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ADMADM
Entrez,  Source
adrenomedullin340.6490.0423No
2PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 11140.4080.0644No
3HSD3B1HSD3B1
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 12290.2990.0765No
4PFKFB1PFKFB1
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 13110.2440.0872No
5TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 23670.2230.0984No
6BCAT1BCAT1
Entrez,  Source
branched chain aminotransferase 1, cytosolic3960.2100.1108No
7DDAH2DDAH2
Entrez,  Source
dimethylarginine dimethylaminohydrolase 25220.1780.1137No
8TSPOTSPO
Entrez,  Source
translocator protein (18kDa)8360.1360.0992No
9EIF2B2EIF2B2
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa9240.1270.1014No
10IL17FIL17F
Entrez,  Source
interleukin 17F9460.1250.1085No
11PLOD1PLOD1
Entrez,  Source
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 110570.1170.1082No
12PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha10680.1160.1155No
13HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 110840.1160.1224No
14DEGS1DEGS1
Entrez,  Source
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)11690.1110.1237No
15SLC5A7SLC5A7
Entrez,  Source
solute carrier family 5 (choline transporter), member 712010.1090.1289No
16IL10IL10
Entrez,  Source
interleukin 1013290.1020.1263No
17ELA2ELA2
Entrez,  Source
elastase 2, neutrophil15220.0930.1182No
18GUK1GUK1
Entrez,  Source
guanylate kinase 115680.0910.1210No
19PAHPAH
Entrez,  Source
phenylalanine hydroxylase16380.0870.1218No
20FARS2FARS2
Entrez,  Source
phenylalanine-tRNA synthetase 2 (mitochondrial)17380.0830.1200No
21GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor19790.0740.1069No
22CD276CD276
Entrez,  Source
CD276 molecule20550.0710.1061No
23ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)21000.0700.1076No
24PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 723000.0640.0969No
25DDX25DDX25
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 2524440.0610.0902No
26MOCS2MOCS2
Entrez,  Source
molybdenum cofactor synthesis 224580.0610.0935No
27DHRS9DHRS9
Entrez,  Source
dehydrogenase/reductase (SDR family) member 926060.0570.0862No
28EIF2AK1EIF2AK1
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 126700.0560.0853No
29UROSUROS
Entrez,  Source
uroporphyrinogen III synthase (congenital erythropoietic porphyria)27550.0540.0826No
30TLR4TLR4
Entrez,  Source
toll-like receptor 428000.0530.0829No
31APBB1APBB1
Entrez,  Source
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)29290.0500.0767No
32EREGEREG
Entrez,  Source
epiregulin29990.0490.0748No
33MRPL41MRPL41
Entrez,  Source
mitochondrial ribosomal protein L4130760.0470.0723No
34EEF2KEEF2K
Entrez,  Source
eukaryotic elongation factor-2 kinase31160.0460.0725No
35GRM8GRM8
Entrez,  Source
glutamate receptor, metabotropic 831790.0450.0709No
36TNFRSF8TNFRSF8
Entrez,  Source
tumor necrosis factor receptor superfamily, member 832950.0430.0651No
37CMPKCMPK
Entrez,  Source
cytidylate kinase33180.0420.0663No
38AKR1D1AKR1D1
Entrez,  Source
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)33230.0420.0689No
39DEFB103ADEFB103A
Entrez,  Source
defensin, beta 103A33310.0420.0713No
40ARPP-19ARPP-19
Entrez,  Source
-33860.0410.0700No
41CHST3CHST3
Entrez,  Source
carbohydrate (chondroitin 6) sulfotransferase 336490.0360.0526No
42BACE2BACE2
Entrez,  Source
beta-site APP-cleaving enzyme 237400.0350.0481No
43LTA4HLTA4H
Entrez,  Source
leukotriene A4 hydrolase37670.0340.0485No
44EIF5EIF5
Entrez,  Source
eukaryotic translation initiation factor 543150.0250.0087No
45HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 243470.0250.0080No
46INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)45960.021-0.0094No
47HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 146550.020-0.0124No
48ATF4ATF4
Entrez,  Source
activating transcription factor 4 (tax-responsive enhancer element B67)46620.020-0.0114No
49AGPAT1AGPAT1
Entrez,  Source
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)46980.020-0.0127No
50EIF4A2EIF4A2
Entrez,  Source
eukaryotic translation initiation factor 4A, isoform 248060.018-0.0196No
51IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)49530.016-0.0296No
52GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone52310.012-0.0498No
53EIF2B1EIF2B1
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa53400.011-0.0573No
54TSC1TSC1
Entrez,  Source
tuberous sclerosis 154100.010-0.0619No
55EIF2AK3EIF2AK3
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 354370.009-0.0632No
56BMP6BMP6
Entrez,  Source
bone morphogenetic protein 654740.009-0.0654No
57PTGS1PTGS1
Entrez,  Source
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)55360.008-0.0695No
58HRSP12HRSP12
Entrez,  Source
heat-responsive protein 1256210.007-0.0754No
59CYP7B1CYP7B1
Entrez,  Source
cytochrome P450, family 7, subfamily B, polypeptide 157830.005-0.0873No
60HBS1LHBS1L
Entrez,  Source
HBS1-like (S. cerevisiae)58400.004-0.0913No
61DHPSDHPS
Entrez,  Source
deoxyhypusine synthase58520.004-0.0919No
62COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)59450.003-0.0987No
63AGPAT6AGPAT6
Entrez,  Source
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)6305-0.002-0.1258No
64GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)6337-0.002-0.1280No
65BCL10BCL10
Entrez,  Source
B-cell CLL/lymphoma 106386-0.003-0.1314No
66UCN2UCN2
Entrez,  Source
urocortin 26539-0.005-0.1427No
67APOA2APOA2
Entrez,  Source
apolipoprotein A-II6545-0.005-0.1427No
68PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)6790-0.008-0.1607No
69HSD3B7HSD3B7
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 76860-0.009-0.1653No
70HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)6866-0.009-0.1651No
71ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 16928-0.010-0.1690No
72IL12BIL12B
Entrez,  Source
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)6942-0.010-0.1693No
73ME1ME1
Entrez,  Source
malic enzyme 1, NADP(+)-dependent, cytosolic7060-0.011-0.1774No
74COQ7COQ7
Entrez,  Source
coenzyme Q7 homolog, ubiquinone (yeast)7099-0.012-0.1795No
75SPNSPN
Entrez,  Source
sialophorin (leukosialin, CD43)7129-0.012-0.1809No
76BBOX1BBOX1
Entrez,  Source
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 17181-0.013-0.1839No
77RPL9RPL9
Entrez,  Source
ribosomal protein L97187-0.013-0.1834No
78CYP11A1CYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 17492-0.017-0.2053No
79ADORA2AADORA2A
Entrez,  Source
adenosine A2a receptor7525-0.017-0.2066No
80EEF1A1EEF1A1
Entrez,  Source
eukaryotic translation elongation factor 1 alpha 17536-0.017-0.2061No
81GCHFRGCHFR
Entrez,  Source
GTP cyclohydrolase I feedback regulator7685-0.019-0.2161No
82OAZ1OAZ1
Entrez,  Source
ornithine decarboxylase antizyme 17785-0.021-0.2222No
83COQ3COQ3
Entrez,  Source
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)7878-0.022-0.2277No
84ADKADK
Entrez,  Source
adenosine kinase7944-0.023-0.2310No
85SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7962-0.023-0.2307No
86FADS1FADS1
Entrez,  Source
fatty acid desaturase 18129-0.025-0.2416No
87MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S78162-0.026-0.2422No
88COPS5COPS5
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)8246-0.027-0.2467No
89RPL26RPL26
Entrez,  Source
ribosomal protein L268372-0.029-0.2542No
90AP3D1AP3D1
Entrez,  Source
adaptor-related protein complex 3, delta 1 subunit8383-0.029-0.2529No
91EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 28447-0.030-0.2556No
92GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase8496-0.031-0.2572No
93ACN9ACN9
Entrez,  Source
ACN9 homolog (S. cerevisiae)8498-0.031-0.2551No
94EIF2B4EIF2B4
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa8566-0.032-0.2580No
95CHST12CHST12
Entrez,  Source
carbohydrate (chondroitin 4) sulfotransferase 128655-0.033-0.2624No
96HSP90AB1HSP90AB1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class B member 18666-0.033-0.2609No
97UMPSUMPS
Entrez,  Source
uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)8780-0.035-0.2671No
98RPL41RPL41
Entrez,  Source
ribosomal protein L418782-0.035-0.2648No
99PTSPTS
Entrez,  Source
6-pyruvoyltetrahydropterin synthase8826-0.035-0.2656No
100WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase8852-0.035-0.2650No
101EIF5AEIF5A
Entrez,  Source
eukaryotic translation initiation factor 5A8947-0.037-0.2696No
102TRSPAP1TRSPAP1
Entrez,  Source
tRNA selenocysteine associated protein 18952-0.037-0.2674No
103RPL19RPL19
Entrez,  Source
ribosomal protein L198959-0.037-0.2653No
104RPS17RPS17
Entrez,  Source
ribosomal protein S179118-0.039-0.2746No
105SIGIRRSIGIRR
Entrez,  Source
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain9143-0.039-0.2737No
106RPL8RPL8
Entrez,  Source
ribosomal protein L89208-0.040-0.2758No
107NQO1NQO1
Entrez,  Source
NAD(P)H dehydrogenase, quinone 19220-0.040-0.2738No
108RPL3RPL3
Entrez,  Source
ribosomal protein L39257-0.041-0.2737No
109ASMTASMT
Entrez,  Source
acetylserotonin O-methyltransferase9278-0.041-0.2724No
110SPRSPR
Entrez,  Source
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)9360-0.043-0.2756No
111GLMNGLMN
Entrez,  Source
glomulin, FKBP associated protein9440-0.044-0.2785No
112COASYCOASY
Entrez,  Source
Coenzyme A synthase9510-0.045-0.2806No
113ABCF1ABCF1
Entrez,  Source
ATP-binding cassette, sub-family F (GCN20), member 19738-0.049-0.2945No
114RPL5RPL5
Entrez,  Source
ribosomal protein L59787-0.050-0.2947No
115RPL37RPL37
Entrez,  Source
ribosomal protein L379799-0.050-0.2921No
116RPL4RPL4
Entrez,  Source
ribosomal protein L49822-0.051-0.2902No
117RPL6RPL6
Entrez,  Source
ribosomal protein L69882-0.052-0.2912No
118HPRT1HPRT1
Entrez,  Source
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)9884-0.052-0.2877No
119MIFMIF
Entrez,  Source
macrophage migration inhibitory factor (glycosylation-inhibiting factor)10013-0.054-0.2937No
120RPL29RPL29
Entrez,  Source
ribosomal protein L2910090-0.055-0.2957Yes
121RPS2RPS2
Entrez,  Source
ribosomal protein S210123-0.056-0.2942Yes
122EIF2B3EIF2B3
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa10129-0.056-0.2908Yes
123IL4IL4
Entrez,  Source
interleukin 410138-0.056-0.2875Yes
124RPL11RPL11
Entrez,  Source
ribosomal protein L1110157-0.056-0.2850Yes
125RPL31RPL31
Entrez,  Source
ribosomal protein L3110162-0.056-0.2814Yes
126GMPSGMPS
Entrez,  Source
guanine monphosphate synthetase10172-0.056-0.2782Yes
127DARSDARS
Entrez,  Source
aspartyl-tRNA synthetase10246-0.057-0.2798Yes
128RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A10285-0.058-0.2787Yes
129ALDH9A1ALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A110414-0.060-0.2842Yes
130NDST1NDST1
Entrez,  Source
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 110484-0.062-0.2852Yes
131RPL18RPL18
Entrez,  Source
ribosomal protein L1810558-0.063-0.2864Yes
132SFTPDSFTPD
Entrez,  Source
surfactant, pulmonary-associated protein D10726-0.067-0.2944Yes
133CYP27B1CYP27B1
Entrez,  Source
cytochrome P450, family 27, subfamily B, polypeptide 110795-0.068-0.2949Yes
134RPS10RPS10
Entrez,  Source
ribosomal protein S1010808-0.069-0.2911Yes
135AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 110838-0.069-0.2885Yes
136RPL15RPL15
Entrez,  Source
ribosomal protein L1510874-0.070-0.2863Yes
137RPS9RPS9
Entrez,  Source
ribosomal protein S910906-0.071-0.2837Yes
138PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase10929-0.072-0.2804Yes
139RPL28RPL28
Entrez,  Source
ribosomal protein L2810952-0.072-0.2771Yes
140TYMSTYMS
Entrez,  Source
thymidylate synthetase10993-0.073-0.2751Yes
141KARSKARS
Entrez,  Source
lysyl-tRNA synthetase11005-0.073-0.2709Yes
142RPL7RPL7
Entrez,  Source
ribosomal protein L711020-0.074-0.2668Yes
143RPL30RPL30
Entrez,  Source
ribosomal protein L3011059-0.075-0.2646Yes
144RPS11RPS11
Entrez,  Source
ribosomal protein S1111120-0.076-0.2639Yes
145SCYE1SCYE1
Entrez,  Source
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)11138-0.077-0.2599Yes
146RPS5RPS5
Entrez,  Source
ribosomal protein S511241-0.080-0.2621Yes
147CPOXCPOX
Entrez,  Source
coproporphyrinogen oxidase11247-0.080-0.2570Yes
148RPS27RPS27
Entrez,  Source
ribosomal protein S27 (metallopanstimulin 1)11258-0.080-0.2522Yes
149MRPL23MRPL23
Entrez,  Source
mitochondrial ribosomal protein L2311272-0.081-0.2476Yes
150EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)11286-0.081-0.2430Yes
151RPL21RPL21
Entrez,  Source
ribosomal protein L2111315-0.082-0.2395Yes
152RPL13RPL13
Entrez,  Source
ribosomal protein L1311394-0.084-0.2396Yes
153RPS3RPS3
Entrez,  Source
ribosomal protein S311521-0.087-0.2432Yes
154MTIF2MTIF2
Entrez,  Source
mitochondrial translational initiation factor 211529-0.087-0.2376Yes
155RPL24RPL24
Entrez,  Source
ribosomal protein L2411552-0.088-0.2332Yes
156BRCA1BRCA1
Entrez,  Source
breast cancer 1, early onset11628-0.090-0.2327Yes
157ALADALAD
Entrez,  Source
aminolevulinate, delta-, dehydratase11672-0.091-0.2297Yes
158RPS12RPS12
Entrez,  Source
ribosomal protein S1211705-0.092-0.2258Yes
159EIF1EIF1
Entrez,  Source
eukaryotic translation initiation factor 111741-0.093-0.2220Yes
160DGAT2DGAT2
Entrez,  Source
diacylglycerol O-acyltransferase homolog 2 (mouse)11757-0.094-0.2166Yes
161AARSAARS
Entrez,  Source
alanyl-tRNA synthetase11763-0.094-0.2105Yes
162RPL35RPL35
Entrez,  Source
ribosomal protein L3511865-0.098-0.2114Yes
163GCLMGCLM
Entrez,  Source
glutamate-cysteine ligase, modifier subunit12046-0.105-0.2179Yes
164RPL22RPL22
Entrez,  Source
ribosomal protein L2212075-0.106-0.2127Yes
165RPL14RPL14
Entrez,  Source
ribosomal protein L1412085-0.107-0.2060Yes
166EIF2B5EIF2B5
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa12127-0.108-0.2016Yes
167ETF1ETF1
Entrez,  Source
eukaryotic translation termination factor 112179-0.110-0.1979Yes
168YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase12233-0.113-0.1941Yes
169CD28CD28
Entrez,  Source
CD28 molecule12261-0.114-0.1882Yes
170INHAINHA
Entrez,  Source
inhibin, alpha12340-0.118-0.1860Yes
171PABPC4PABPC4
Entrez,  Source
poly(A) binding protein, cytoplasmic 4 (inducible form)12431-0.123-0.1843Yes
172RPS19RPS19
Entrez,  Source
ribosomal protein S1912470-0.125-0.1786Yes
173EIF4BEIF4B
Entrez,  Source
eukaryotic translation initiation factor 4B12532-0.130-0.1742Yes
174GCH1GCH1
Entrez,  Source
GTP cyclohydrolase 1 (dopa-responsive dystonia)12570-0.133-0.1678Yes
175CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I12594-0.134-0.1603Yes
176SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 1012799-0.152-0.1653Yes
177PPATPPAT
Entrez,  Source
phosphoribosyl pyrophosphate amidotransferase12816-0.154-0.1558Yes
178GCLCGCLC
Entrez,  Source
glutamate-cysteine ligase, catalytic subunit12866-0.161-0.1484Yes
179UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase12882-0.162-0.1384Yes
180DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)12922-0.168-0.1297Yes
181GAMTGAMT
Entrez,  Source
guanidinoacetate N-methyltransferase12960-0.175-0.1205Yes
182RPL39RPL39
Entrez,  Source
ribosomal protein L3913115-0.215-0.1174Yes
183FADS2FADS2
Entrez,  Source
fatty acid desaturase 213155-0.226-0.1047Yes
184ABCA1ABCA1
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 113254-0.302-0.0912Yes
185GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)13266-0.315-0.0703Yes
186CD74CD74
Entrez,  Source
CD74 molecule, major histocompatibility complex, class II invariant chain13324-0.530-0.0380Yes
187LTBLTB
Entrez,  Source
lymphotoxin beta (TNF superfamily, member 3)13327-0.5680.0011Yes
Table: GSEA details [plain text format]



Fig 2: CELLULAR_BIOSYNTHETIC_PROCESS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CELLULAR_BIOSYNTHETIC_PROCESS: Random ES distribution   
Gene set null distribution of ES for CELLULAR_BIOSYNTHETIC_PROCESS