Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CELL_CELL_ADHESION |
| Enrichment Score (ES) | 0.6142017 |
| Normalized Enrichment Score (NES) | 1.9621682 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008053113 |
| FWER p-Value | 0.328 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 7 | 0.940 | 0.1803 | Yes |
| 2 | MGP | MGP Entrez, Source | matrix Gla protein | 62 | 0.533 | 0.2787 | Yes |
| 3 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 128 | 0.391 | 0.3490 | Yes |
| 4 | CLDN1 | CLDN1 Entrez, Source | claudin 1 | 157 | 0.357 | 0.4156 | Yes |
| 5 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 195 | 0.324 | 0.4752 | Yes |
| 6 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 255 | 0.280 | 0.5245 | Yes |
| 7 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 375 | 0.218 | 0.5575 | Yes |
| 8 | CLDN3 | CLDN3 Entrez, Source | claudin 3 | 504 | 0.181 | 0.5827 | Yes |
| 9 | ACVRL1 | ACVRL1 Entrez, Source | activin A receptor type II-like 1 | 678 | 0.153 | 0.5991 | Yes |
| 10 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 827 | 0.136 | 0.6142 | Yes |
| 11 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 2131 | 0.069 | 0.5294 | No |
| 12 | NLGN1 | NLGN1 Entrez, Source | neuroligin 1 | 2284 | 0.065 | 0.5305 | No |
| 13 | CNTN4 | CNTN4 Entrez, Source | contactin 4 | 2322 | 0.064 | 0.5400 | No |
| 14 | CLDN4 | CLDN4 Entrez, Source | claudin 4 | 2429 | 0.061 | 0.5438 | No |
| 15 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2472 | 0.060 | 0.5523 | No |
| 16 | CD93 | CD93 Entrez, Source | CD93 molecule | 2691 | 0.055 | 0.5465 | No |
| 17 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 2770 | 0.053 | 0.5509 | No |
| 18 | NPTN | NPTN Entrez, Source | neuroplastin | 2925 | 0.050 | 0.5490 | No |
| 19 | CLDN19 | CLDN19 Entrez, Source | claudin 19 | 3194 | 0.045 | 0.5374 | No |
| 20 | ATP2C1 | ATP2C1 Entrez, Source | ATPase, Ca++ transporting, type 2C, member 1 | 3896 | 0.032 | 0.4908 | No |
| 21 | CLDN5 | CLDN5 Entrez, Source | claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) | 4087 | 0.029 | 0.4821 | No |
| 22 | ROBO2 | ROBO2 Entrez, Source | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 4299 | 0.025 | 0.4711 | No |
| 23 | AMIGO3 | AMIGO3 Entrez, Source | adhesion molecule with Ig-like domain 3 | 4442 | 0.023 | 0.4649 | No |
| 24 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 4616 | 0.021 | 0.4559 | No |
| 25 | CD47 | CD47 Entrez, Source | CD47 molecule | 5066 | 0.014 | 0.4249 | No |
| 26 | LGALS7 | LGALS7 Entrez, Source | lectin, galactoside-binding, soluble, 7 (galectin 7) | 5154 | 0.013 | 0.4208 | No |
| 27 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 5466 | 0.009 | 0.3991 | No |
| 28 | SYK | SYK Entrez, Source | spleen tyrosine kinase | 5570 | 0.007 | 0.3928 | No |
| 29 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 5892 | 0.004 | 0.3693 | No |
| 30 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 6070 | 0.001 | 0.3563 | No |
| 31 | PKD1 | PKD1 Entrez, Source | polycystic kidney disease 1 (autosomal dominant) | 6183 | -0.000 | 0.3479 | No |
| 32 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 6196 | -0.001 | 0.3471 | No |
| 33 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 6253 | -0.001 | 0.3432 | No |
| 34 | BCL10 | BCL10 Entrez, Source | B-cell CLL/lymphoma 10 | 6386 | -0.003 | 0.3338 | No |
| 35 | CALCA | CALCA Entrez, Source | calcitonin/calcitonin-related polypeptide, alpha | 6521 | -0.005 | 0.3246 | No |
| 36 | EMCN | EMCN Entrez, Source | endomucin | 6694 | -0.007 | 0.3130 | No |
| 37 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 6951 | -0.010 | 0.2957 | No |
| 38 | NINJ2 | NINJ2 Entrez, Source | ninjurin 2 | 7033 | -0.011 | 0.2917 | No |
| 39 | CLDN8 | CLDN8 Entrez, Source | claudin 8 | 8413 | -0.030 | 0.1937 | No |
| 40 | CLDN11 | CLDN11 Entrez, Source | claudin 11 (oligodendrocyte transmembrane protein) | 8492 | -0.031 | 0.1937 | No |
| 41 | AMIGO2 | AMIGO2 Entrez, Source | adhesion molecule with Ig-like domain 2 | 8707 | -0.034 | 0.1841 | No |
| 42 | ROBO1 | ROBO1 Entrez, Source | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 9015 | -0.038 | 0.1683 | No |
| 43 | DLG1 | DLG1 Entrez, Source | discs, large homolog 1 (Drosophila) | 9232 | -0.041 | 0.1599 | No |
| 44 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 9586 | -0.047 | 0.1423 | No |
| 45 | GTPBP4 | GTPBP4 Entrez, Source | GTP binding protein 4 | 9786 | -0.050 | 0.1369 | No |
| 46 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 10692 | -0.066 | 0.0815 | No |
| 47 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 11286 | -0.081 | 0.0525 | No |
| 48 | NCAM2 | NCAM2 Entrez, Source | neural cell adhesion molecule 2 | 11610 | -0.089 | 0.0453 | No |
| 49 | REG3A | REG3A Entrez, Source | regenerating islet-derived 3 alpha | 12004 | -0.103 | 0.0356 | No |
| 50 | CLDN16 | CLDN16 Entrez, Source | claudin 16 | 12102 | -0.107 | 0.0490 | No |
| 51 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12189 | -0.111 | 0.0638 | No |
| 52 | CLDN14 | CLDN14 Entrez, Source | claudin 14 | 12357 | -0.119 | 0.0741 | No |
