Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | CELL_CYCLE_CHECKPOINT |
| Enrichment Score (ES) | -0.60972905 |
| Normalized Enrichment Score (NES) | -1.6446089 |
| Nominal p-value | 0.020501139 |
| FDR q-value | 0.18260045 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 406 | 0.208 | 0.1127 | No |
| 2 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 2991 | 0.049 | -0.0477 | No |
| 3 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 5139 | 0.013 | -0.1996 | No |
| 4 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5788 | 0.005 | -0.2450 | No |
| 5 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 7654 | -0.019 | -0.3720 | No |
| 6 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 7980 | -0.023 | -0.3804 | No |
| 7 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8883 | -0.036 | -0.4234 | No |
| 8 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11368 | -0.083 | -0.5525 | Yes |
| 9 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11628 | -0.090 | -0.5103 | Yes |
| 10 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.4752 | Yes |
| 11 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 12427 | -0.123 | -0.4097 | Yes |
| 12 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 12718 | -0.143 | -0.3331 | Yes |
| 13 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 12763 | -0.148 | -0.2346 | Yes |
| 14 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13022 | -0.190 | -0.1234 | Yes |
| 15 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13114 | -0.214 | 0.0171 | Yes |
