Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CHIARETTI_T_ALL |
| Enrichment Score (ES) | 0.5079459 |
| Normalized Enrichment Score (NES) | 1.8903947 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01745226 |
| FWER p-Value | 0.685 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 5 | 0.972 | 0.0555 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.1020 | Yes |
| 3 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 11 | 0.815 | 0.1489 | Yes |
| 4 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 19 | 0.707 | 0.1890 | Yes |
| 5 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 42 | 0.616 | 0.2227 | Yes |
| 6 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 47 | 0.597 | 0.2567 | Yes |
| 7 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 73 | 0.484 | 0.2826 | Yes |
| 8 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 104 | 0.424 | 0.3047 | Yes |
| 9 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 118 | 0.402 | 0.3268 | Yes |
| 10 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 140 | 0.372 | 0.3466 | Yes |
| 11 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 142 | 0.371 | 0.3678 | Yes |
| 12 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 165 | 0.350 | 0.3862 | Yes |
| 13 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 183 | 0.333 | 0.4041 | Yes |
| 14 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 218 | 0.309 | 0.4193 | Yes |
| 15 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 276 | 0.263 | 0.4301 | Yes |
| 16 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 358 | 0.227 | 0.4370 | Yes |
| 17 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 361 | 0.225 | 0.4498 | Yes |
| 18 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 414 | 0.206 | 0.4577 | Yes |
| 19 | S100A4 | S100A4 Entrez, Source | S100 calcium binding protein A4 | 450 | 0.195 | 0.4663 | Yes |
| 20 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 550 | 0.172 | 0.4687 | Yes |
| 21 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 646 | 0.158 | 0.4706 | Yes |
| 22 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 663 | 0.156 | 0.4783 | Yes |
| 23 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 742 | 0.145 | 0.4808 | Yes |
| 24 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 798 | 0.140 | 0.4846 | Yes |
| 25 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 827 | 0.136 | 0.4904 | Yes |
| 26 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 841 | 0.135 | 0.4971 | Yes |
| 27 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 881 | 0.131 | 0.5017 | Yes |
| 28 | CD69 | CD69 Entrez, Source | CD69 molecule | 898 | 0.129 | 0.5079 | Yes |
| 29 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 1208 | 0.109 | 0.4908 | No |
| 30 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 1285 | 0.105 | 0.4911 | No |
| 31 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1297 | 0.104 | 0.4962 | No |
| 32 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 1444 | 0.096 | 0.4907 | No |
| 33 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 1487 | 0.095 | 0.4930 | No |
| 34 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 1492 | 0.094 | 0.4981 | No |
| 35 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 1499 | 0.094 | 0.5030 | No |
| 36 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1672 | 0.086 | 0.4949 | No |
| 37 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 1676 | 0.086 | 0.4997 | No |
| 38 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 1774 | 0.082 | 0.4970 | No |
| 39 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 1914 | 0.076 | 0.4908 | No |
| 40 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1925 | 0.075 | 0.4944 | No |
| 41 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2100 | 0.070 | 0.4852 | No |
| 42 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 2181 | 0.068 | 0.4831 | No |
| 43 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 2222 | 0.067 | 0.4839 | No |
| 44 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 2231 | 0.066 | 0.4871 | No |
| 45 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 2278 | 0.065 | 0.4873 | No |
| 46 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 2366 | 0.063 | 0.4844 | No |
| 47 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 2447 | 0.061 | 0.4818 | No |
| 48 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 2697 | 0.055 | 0.4661 | No |
| 49 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 2779 | 0.053 | 0.4630 | No |
| 50 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 2895 | 0.051 | 0.4573 | No |
| 51 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 2927 | 0.050 | 0.4578 | No |
| 52 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 3036 | 0.048 | 0.4524 | No |
| 53 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 3052 | 0.047 | 0.4539 | No |
| 54 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 3107 | 0.046 | 0.4525 | No |
| 55 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 3143 | 0.046 | 0.4525 | No |
| 56 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 3209 | 0.044 | 0.4501 | No |
| 57 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 3216 | 0.044 | 0.4522 | No |
| 58 | SNF1LK | SNF1LK Entrez, Source | SNF1-like kinase | 3570 | 0.037 | 0.4276 | No |
| 59 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 3646 | 0.036 | 0.4240 | No |
| 60 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 3663 | 0.036 | 0.4249 | No |
| 61 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 3712 | 0.035 | 0.4232 | No |
| 62 | MAL | MAL Entrez, Source | mal, T-cell differentiation protein | 3748 | 0.034 | 0.4226 | No |
| 63 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 4260 | 0.026 | 0.3853 | No |
| 64 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 4288 | 0.026 | 0.3848 | No |
| 65 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 4344 | 0.025 | 0.3820 | No |
| 66 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 4566 | 0.022 | 0.3665 | No |
| 67 | CD2 | CD2 Entrez, Source | CD2 molecule | 4735 | 0.019 | 0.3549 | No |
| 68 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 5202 | 0.013 | 0.3203 | No |
| 69 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 5266 | 0.012 | 0.3162 | No |
| 70 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 5296 | 0.011 | 0.3147 | No |
| 71 | RUNX3 | RUNX3 Entrez, Source | runt-related transcription factor 3 | 5356 | 0.010 | 0.3108 | No |
| 72 | CTSH | CTSH Entrez, Source | cathepsin H | 5387 | 0.010 | 0.3091 | No |
| 73 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 5464 | 0.009 | 0.3039 | No |
| 74 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 5643 | 0.006 | 0.2907 | No |
| 75 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 5737 | 0.005 | 0.2840 | No |
| 76 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 5830 | 0.004 | 0.2773 | No |
| 77 | RAP2B | RAP2B Entrez, Source | RAP2B, member of RAS oncogene family | 5893 | 0.004 | 0.2728 | No |
| 78 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 5899 | 0.003 | 0.2726 | No |
| 79 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 6191 | -0.000 | 0.2506 | No |
| 80 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 6193 | -0.000 | 0.2505 | No |
| 81 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6239 | -0.001 | 0.2472 | No |
| 82 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 6558 | -0.005 | 0.2234 | No |
| 83 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 6663 | -0.007 | 0.2159 | No |
| 84 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 6866 | -0.009 | 0.2011 | No |
| 85 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 6887 | -0.009 | 0.2001 | No |
| 86 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 6967 | -0.010 | 0.1947 | No |
| 87 | CLEC11A | CLEC11A Entrez, Source | C-type lectin domain family 11, member A | 7198 | -0.013 | 0.1781 | No |
| 88 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 7435 | -0.016 | 0.1611 | No |
| 89 | CD8A | CD8A Entrez, Source | CD8a molecule | 7480 | -0.016 | 0.1587 | No |
| 90 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 7648 | -0.019 | 0.1471 | No |
| 91 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 7715 | -0.020 | 0.1433 | No |
| 92 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 7804 | -0.021 | 0.1378 | No |
| 93 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 7852 | -0.021 | 0.1355 | No |
| 94 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 7975 | -0.023 | 0.1276 | No |
| 95 | CD52 | CD52 Entrez, Source | CD52 molecule | 8286 | -0.028 | 0.1057 | No |
| 96 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 8322 | -0.028 | 0.1046 | No |
| 97 | SLC4A1 | SLC4A1 Entrez, Source | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 8397 | -0.029 | 0.1007 | No |
| 98 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 8408 | -0.029 | 0.1016 | No |
| 99 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 8721 | -0.034 | 0.0800 | No |
| 100 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 8730 | -0.034 | 0.0813 | No |
| 101 | ARID5A | ARID5A Entrez, Source | AT rich interactive domain 5A (MRF1-like) | 8765 | -0.034 | 0.0807 | No |
| 102 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 8800 | -0.035 | 0.0801 | No |
| 103 | EPHB6 | EPHB6 Entrez, Source | EPH receptor B6 | 8855 | -0.036 | 0.0781 | No |
| 104 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 8876 | -0.036 | 0.0786 | No |
| 105 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 9332 | -0.042 | 0.0466 | No |
| 106 | ST18 | ST18 Entrez, Source | suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) | 9371 | -0.043 | 0.0462 | No |
| 107 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 9627 | -0.047 | 0.0296 | No |
| 108 | CD200 | CD200 Entrez, Source | CD200 molecule | 9804 | -0.050 | 0.0191 | No |
| 109 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 9985 | -0.053 | 0.0086 | No |
| 110 | ZBTB16 | ZBTB16 Entrez, Source | zinc finger and BTB domain containing 16 | 10088 | -0.055 | 0.0040 | No |
| 111 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 10706 | -0.066 | -0.0389 | No |
| 112 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.0423 | No |
| 113 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 10807 | -0.069 | -0.0385 | No |
| 114 | SELL | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 10918 | -0.071 | -0.0428 | No |
| 115 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 11182 | -0.078 | -0.0582 | No |
| 116 | SPON1 | SPON1 Entrez, Source | spondin 1, extracellular matrix protein | 11183 | -0.078 | -0.0538 | No |
| 117 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 11295 | -0.081 | -0.0575 | No |
| 118 | IGJ | IGJ Entrez, Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 11533 | -0.087 | -0.0704 | No |
| 119 | FXYD2 | FXYD2 Entrez, Source | FXYD domain containing ion transport regulator 2 | 11644 | -0.090 | -0.0736 | No |
| 120 | LAT | LAT Entrez, Source | linker for activation of T cells | 11646 | -0.090 | -0.0685 | No |
| 121 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 11816 | -0.096 | -0.0758 | No |
| 122 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11920 | -0.100 | -0.0778 | No |
| 123 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 12100 | -0.107 | -0.0852 | No |
| 124 | GARNL1 | GARNL1 Entrez, Source | GTPase activating Rap/RanGAP domain-like 1 | 12154 | -0.109 | -0.0830 | No |
| 125 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 12283 | -0.115 | -0.0860 | No |
| 126 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 12463 | -0.125 | -0.0924 | No |
| 127 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12570 | -0.133 | -0.0928 | No |
| 128 | CD97 | CD97 Entrez, Source | CD97 molecule | 12593 | -0.134 | -0.0868 | No |
| 129 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12609 | -0.135 | -0.0801 | No |
| 130 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 12646 | -0.138 | -0.0750 | No |
| 131 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 12743 | -0.146 | -0.0739 | No |
| 132 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 12782 | -0.150 | -0.0681 | No |
| 133 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 12966 | -0.175 | -0.0719 | No |
| 134 | H1F0 | H1F0 Entrez, Source | H1 histone family, member 0 | 13032 | -0.193 | -0.0657 | No |
| 135 | RCBTB2 | RCBTB2 Entrez, Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 13039 | -0.195 | -0.0550 | No |
| 136 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 13070 | -0.202 | -0.0457 | No |
| 137 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13196 | -0.252 | -0.0407 | No |
| 138 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13227 | -0.274 | -0.0272 | No |
| 139 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 13229 | -0.277 | -0.0114 | No |
| 140 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 13280 | -0.345 | 0.0047 | No |
