Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetCHIARETTI_T_ALL_DIFF
Enrichment Score (ES)0.49653357
Normalized Enrichment Score (NES)1.899382
Nominal p-value0.0
FDR q-value0.015885752
FWER p-Value0.631
Table: GSEA Results Summary



Fig 1: Enrichment plot: CHIARETTI_T_ALL_DIFF   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 750.9720.0536Yes
2ANXA1ANXA1
Entrez,  Source
annexin A1100.8150.0986Yes
3CCND2CCND2
Entrez,  Source
cyclin D2110.8150.1439Yes
4ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 2190.7070.1827Yes
5RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa420.6160.2152Yes
6LGALS1LGALS1
Entrez,  Source
lectin, galactoside-binding, soluble, 1 (galectin 1)470.5970.2480Yes
7MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)730.4840.2731Yes
8SERPINE2SERPINE2
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 21040.4240.2943Yes
9CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 21180.4020.3157Yes
10RGS1RGS1
Entrez,  Source
regulator of G-protein signalling 11400.3720.3348Yes
11FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog1420.3710.3553Yes
12AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)1650.3500.3730Yes
13CCL3CCL3
Entrez,  Source
chemokine (C-C motif) ligand 31830.3330.3903Yes
14ATF3ATF3
Entrez,  Source
activating transcription factor 32180.3090.4049Yes
15TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 32760.2630.4152Yes
16EMP3EMP3
Entrez,  Source
epithelial membrane protein 33580.2270.4216Yes
17PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)3610.2250.4340Yes
18PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)4140.2060.4415Yes
19S100A4S100A4
Entrez,  Source
S100 calcium binding protein A44500.1950.4497Yes
20ADFPADFP
Entrez,  Source
adipose differentiation-related protein5500.1720.4518Yes
21ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule6460.1580.4534Yes
22SPRY2SPRY2
Entrez,  Source
sprouty homolog 2 (Drosophila)6630.1560.4608Yes
23PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 17420.1450.4630Yes
24PF4PF4
Entrez,  Source
platelet factor 4 (chemokine (C-X-C motif) ligand 4)7980.1400.4666Yes
25TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)8250.1370.4722Yes
26LMO4LMO4
Entrez,  Source
LIM domain only 48270.1360.4797Yes
27IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 18410.1350.4862Yes
28PTTG1IPPTTG1IP
Entrez,  Source
pituitary tumor-transforming 1 interacting protein8810.1310.4906Yes
29CD69CD69
Entrez,  Source
CD69 molecule8980.1290.4965Yes
30DUSP2DUSP2
Entrez,  Source
dual specificity phosphatase 212080.1090.4792No
31PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule12850.1050.4792No
32DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112970.1040.4842No
33S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1014440.0960.4785No
34PDLIM1PDLIM1
Entrez,  Source
PDZ and LIM domain 1 (elfin)14870.0950.4806No
35SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 114920.0940.4855No
36BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)14990.0940.4903No
37ANXA5ANXA5
Entrez,  Source
annexin A515500.0920.4916No
38TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)16720.0860.4872No
39CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)16760.0860.4917No
40PRSS1PRSS1
Entrez,  Source
protease, serine, 1 (trypsin 1)17210.0840.4930No
41CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta17740.0820.4936No
42WASF1WASF1
Entrez,  Source
WAS protein family, member 119140.0760.4873No
43NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)19250.0750.4907No
44ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)21000.0700.4814No
45ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein21810.0680.4791No
46BCL11ABCL11A
Entrez,  Source
B-cell CLL/lymphoma 11A (zinc finger protein)22220.0670.4798No
47CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor22310.0660.4829No
48HES1HES1
Entrez,  Source
hairy and enhancer of split 1, (Drosophila)22780.0650.4830No
49CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 223660.0630.4799No
50CCL5CCL5
Entrez,  Source
chemokine (C-C motif) ligand 524470.0610.4772No
51CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase26970.0550.4614No
52HIST1H2BLHIST1H2BL
Entrez,  Source
histone cluster 1, H2bl27790.0530.4582No
53PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha28950.0510.4523No
54FRMD4BFRMD4B
Entrez,  Source
FERM domain containing 4B29270.0500.4528No
55MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 130520.0470.4460No
56GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 331070.0460.4445No
57CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)31430.0460.4444No
58NOTCH3NOTCH3
Entrez,  Source
Notch homolog 3 (Drosophila)32090.0440.4419No
59ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 132160.0440.4439No
60SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase35700.0370.4193No
61PTPREPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E36460.0360.4156No
62ALOX5ALOX5
Entrez,  Source
arachidonate 5-lipoxygenase36630.0360.4164No
63TSHRTSHR
Entrez,  Source
thyroid stimulating hormone receptor37120.0350.4147No
64MALMAL
Entrez,  Source
mal, T-cell differentiation protein37480.0340.4139No
65TRHTRH
Entrez,  Source
thyrotropin-releasing hormone40360.0300.3938No
66S100A8S100A8
Entrez,  Source
S100 calcium binding protein A842600.0260.3784No
67DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 642880.0260.3777No
68ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 343440.0250.3749No
69MX1MX1
Entrez,  Source
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)45660.0220.3594No
70CD2CD2
Entrez,  Source
CD2 molecule47350.0190.3477No
71CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)52020.0130.3131No
72FHL1FHL1
Entrez,  Source
four and a half LIM domains 152660.0120.3090No
73ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein52960.0110.3074No
74RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 353560.0100.3035No
75CTSHCTSH
Entrez,  Source
cathepsin H53870.0100.3018No
76ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle54640.0090.2965No
77PPBPPPBP
Entrez,  Source
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)56430.0060.2834No
78PRDX2PRDX2
Entrez,  Source
peroxiredoxin 257370.0050.2766No
79HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like58300.0040.2699No
80RAP2BRAP2B
Entrez,  Source
RAP2B, member of RAS oncogene family58930.0040.2654No
81GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 258990.0030.2652No
82IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 306191-0.0000.2431No
83STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)6193-0.0000.2431No
84CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)6239-0.0010.2397No
85MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase6546-0.0050.2168No
86ALDH1A2ALDH1A2
Entrez,  Source
aldehyde dehydrogenase 1 family, member A26558-0.0050.2163No
87LDLRLDLR
Entrez,  Source
low density lipoprotein receptor (familial hypercholesterolemia)6572-0.0050.2156No
88HOXA5HOXA5
Entrez,  Source
homeobox A56663-0.0070.2091No
89HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)6866-0.0090.1943No
90IL12AIL12A
Entrez,  Source
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)6887-0.0090.1933No
91ITGA6ITGA6
Entrez,  Source
integrin, alpha 66967-0.0100.1879No
92CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A7198-0.0130.1712No
93UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase7435-0.0160.1542No
94CD8ACD8A
Entrez,  Source
CD8a molecule7480-0.0160.1518No
95NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated7648-0.0190.1401No
96MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)7715-0.0200.1362No
97AHRAHR
Entrez,  Source
aryl hydrocarbon receptor7804-0.0210.1307No
98BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 27852-0.0210.1283No
99AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)7975-0.0230.1204No
100IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)8212-0.0270.1040No
101CD52CD52
Entrez,  Source
CD52 molecule8286-0.0280.1000No
102TOB1TOB1
Entrez,  Source
transducer of ERBB2, 18322-0.0280.0989No
103SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)8397-0.0290.0949No
104BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 38408-0.0290.0958No
105QKIQKI
Entrez,  Source
quaking homolog, KH domain RNA binding (mouse)8721-0.0340.0740No
106SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)8730-0.0340.0753No
107ARID5AARID5A
Entrez,  Source
AT rich interactive domain 5A (MRF1-like)8765-0.0340.0746No
108HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed8800-0.0350.0740No
109EPHB6EPHB6
Entrez,  Source
EPH receptor B68855-0.0360.0719No
110LAPTM4BLAPTM4B
Entrez,  Source
lysosomal associated protein transmembrane 4 beta8874-0.0360.0725No
111SOCS2SOCS2
Entrez,  Source
suppressor of cytokine signaling 28876-0.0360.0744No
112IL4RIL4R
Entrez,  Source
interleukin 4 receptor9332-0.0420.0423No
113ST18ST18
Entrez,  Source
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)9371-0.0430.0418No
114IRF7IRF7
Entrez,  Source
interferon regulatory factor 79469-0.0450.0369No
115CATCAT
Entrez,  Source
catalase9526-0.0460.0352No
116ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 69627-0.0470.0302No
117CD200CD200
Entrez,  Source
CD200 molecule9804-0.0500.0197No
118SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 39985-0.0530.0090No
119ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1610088-0.0550.0043No
120S100A9S100A9
Entrez,  Source
S100 calcium binding protein A910706-0.066-0.0388No
121STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa10803-0.068-0.0423No
122FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)10807-0.069-0.0387No
123SELLSELL
Entrez,  Source
selectin L (lymphocyte adhesion molecule 1)10918-0.071-0.0431No
124SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11182-0.078-0.0587No
125SPON1SPON1
Entrez,  Source
spondin 1, extracellular matrix protein11183-0.078-0.0543No
126CSDACSDA
Entrez,  Source
cold shock domain protein A11295-0.081-0.0582No
127IGJIGJ
Entrez,  Source
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides11533-0.087-0.0713No
128FXYD2FXYD2
Entrez,  Source
FXYD domain containing ion transport regulator 211644-0.090-0.0747No
129LATLAT
Entrez,  Source
linker for activation of T cells11646-0.090-0.0698No
130LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)11816-0.096-0.0772No
131TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)11920-0.100-0.0795No
132ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa12100-0.107-0.0871No
133GARNL1GARNL1
Entrez,  Source
GTPase activating Rap/RanGAP domain-like 112154-0.109-0.0850No
134LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12283-0.115-0.0883No
135USP1USP1
Entrez,  Source
ubiquitin specific peptidase 112463-0.125-0.0950No
136GCH1GCH1
Entrez,  Source
GTP cyclohydrolase 1 (dopa-responsive dystonia)12570-0.133-0.0956No
137CD97CD97
Entrez,  Source
CD97 molecule12593-0.134-0.0898No
138PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 212609-0.135-0.0835No
139SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 212646-0.138-0.0786No
140IFI44IFI44
Entrez,  Source
interferon-induced protein 4412681-0.140-0.0734No
141DDIT4DDIT4
Entrez,  Source
DNA-damage-inducible transcript 412743-0.146-0.0699No
142RASGRP1RASGRP1
Entrez,  Source
RAS guanyl releasing protein 1 (calcium and DAG-regulated)12782-0.150-0.0644No
143KLF10KLF10
Entrez,  Source
Kruppel-like factor 1012966-0.175-0.0686No
144H1F0H1F0
Entrez,  Source
H1 histone family, member 013032-0.193-0.0628No
145RCBTB2RCBTB2
Entrez,  Source
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 213039-0.195-0.0524No
146CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 413070-0.202-0.0435No
147SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)13196-0.252-0.0389No
148G0S2G0S2
Entrez,  Source
G0/G1switch 213227-0.274-0.0260No
149PSPHPSPH
Entrez,  Source
phosphoserine phosphatase13229-0.277-0.0107No
150ARNTLARNTL
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator-like13280-0.3450.0047No
Table: GSEA details [plain text format]



Fig 2: CHIARETTI_T_ALL_DIFF   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CHIARETTI_T_ALL_DIFF: Random ES distribution   
Gene set null distribution of ES for CHIARETTI_T_ALL_DIFF