Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CMV_24HRS_DN |
| Enrichment Score (ES) | 0.6404846 |
| Normalized Enrichment Score (NES) | 2.0694947 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0028631464 |
| FWER p-Value | 0.064 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.1190 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 10 | 0.815 | 0.2114 | Yes |
| 3 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.3028 | Yes |
| 4 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 15 | 0.737 | 0.3867 | Yes |
| 5 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 28 | 0.668 | 0.4619 | Yes |
| 6 | ADM | ADM Entrez, Source | adrenomedullin | 34 | 0.649 | 0.5355 | Yes |
| 7 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 337 | 0.234 | 0.5394 | Yes |
| 8 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 351 | 0.229 | 0.5646 | Yes |
| 9 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 406 | 0.208 | 0.5842 | Yes |
| 10 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 460 | 0.193 | 0.6022 | Yes |
| 11 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 480 | 0.186 | 0.6220 | Yes |
| 12 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 577 | 0.168 | 0.6339 | Yes |
| 13 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 738 | 0.146 | 0.6384 | Yes |
| 14 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 1001 | 0.121 | 0.6325 | Yes |
| 15 | SGCG | SGCG Entrez, Source | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 1085 | 0.116 | 0.6395 | Yes |
| 16 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 1236 | 0.108 | 0.6405 | Yes |
| 17 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 1439 | 0.096 | 0.6363 | No |
| 18 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 1627 | 0.088 | 0.6322 | No |
| 19 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 2324 | 0.064 | 0.5871 | No |
| 20 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2713 | 0.055 | 0.5642 | No |
| 21 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 2822 | 0.052 | 0.5620 | No |
| 22 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 2961 | 0.050 | 0.5573 | No |
| 23 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 3082 | 0.047 | 0.5536 | No |
| 24 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3414 | 0.040 | 0.5333 | No |
| 25 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 4259 | 0.026 | 0.4727 | No |
| 26 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 4794 | 0.018 | 0.4346 | No |
| 27 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 4901 | 0.017 | 0.4286 | No |
| 28 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 5027 | 0.015 | 0.4209 | No |
| 29 | EPO | EPO Entrez, Source | erythropoietin | 5541 | 0.008 | 0.3831 | No |
| 30 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 5926 | 0.003 | 0.3546 | No |
| 31 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 7209 | -0.013 | 0.2596 | No |
| 32 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 7343 | -0.015 | 0.2513 | No |
| 33 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 7491 | -0.017 | 0.2421 | No |
| 34 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 7804 | -0.021 | 0.2210 | No |
| 35 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 8524 | -0.031 | 0.1705 | No |
| 36 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 8993 | -0.037 | 0.1395 | No |
| 37 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 9012 | -0.038 | 0.1425 | No |
| 38 | HIVEP2 | HIVEP2 Entrez, Source | human immunodeficiency virus type I enhancer binding protein 2 | 9216 | -0.040 | 0.1318 | No |
| 39 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 9270 | -0.041 | 0.1325 | No |
| 40 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 10107 | -0.055 | 0.0759 | No |
| 41 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 10417 | -0.061 | 0.0595 | No |
| 42 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 10438 | -0.061 | 0.0650 | No |
| 43 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 10816 | -0.069 | 0.0444 | No |
| 44 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 10964 | -0.073 | 0.0416 | No |
| 45 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10990 | -0.073 | 0.0481 | No |
| 46 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 11134 | -0.077 | 0.0461 | No |
| 47 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 11271 | -0.081 | 0.0450 | No |
| 48 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 12182 | -0.111 | -0.0109 | No |
| 49 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 12432 | -0.123 | -0.0156 | No |
| 50 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12567 | -0.133 | -0.0106 | No |
| 51 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 12892 | -0.163 | -0.0164 | No |
| 52 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13029 | -0.193 | -0.0046 | No |
| 53 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 13189 | -0.247 | 0.0115 | No |
