Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CROONQUIST_IL6_STROMA_UP |
| Enrichment Score (ES) | 0.8316547 |
| Normalized Enrichment Score (NES) | 2.454606 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 3 | 1.046 | 0.1292 | Yes |
| 2 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 5 | 0.972 | 0.2494 | Yes |
| 3 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12 | 0.803 | 0.3483 | Yes |
| 4 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 32 | 0.660 | 0.4285 | Yes |
| 5 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 42 | 0.616 | 0.5041 | Yes |
| 6 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 56 | 0.562 | 0.5726 | Yes |
| 7 | LOX | LOX Entrez, Source | lysyl oxidase | 82 | 0.465 | 0.6283 | Yes |
| 8 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 118 | 0.402 | 0.6753 | Yes |
| 9 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 142 | 0.371 | 0.7195 | Yes |
| 10 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 183 | 0.333 | 0.7577 | Yes |
| 11 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 234 | 0.297 | 0.7907 | Yes |
| 12 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 427 | 0.202 | 0.8013 | Yes |
| 13 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 567 | 0.170 | 0.8119 | Yes |
| 14 | IER3 | IER3 Entrez, Source | immediate early response 3 | 598 | 0.165 | 0.8300 | Yes |
| 15 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 888 | 0.130 | 0.8245 | Yes |
| 16 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 1137 | 0.113 | 0.8198 | Yes |
| 17 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1297 | 0.104 | 0.8208 | Yes |
| 18 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 1439 | 0.096 | 0.8221 | Yes |
| 19 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 1470 | 0.095 | 0.8317 | Yes |
| 20 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 3209 | 0.044 | 0.7066 | No |
| 21 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 3468 | 0.039 | 0.6921 | No |
| 22 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | 0.5826 | No |
| 23 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 6410 | -0.003 | 0.4737 | No |
| 24 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 9270 | -0.041 | 0.2640 | No |
| 25 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 9694 | -0.049 | 0.2383 | No |
| 26 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 10417 | -0.061 | 0.1916 | No |
| 27 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 11567 | -0.088 | 0.1162 | No |
| 28 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 12653 | -0.138 | 0.0517 | No |
