Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | DER_IFNA_UP |
| Enrichment Score (ES) | -0.49190408 |
| Normalized Enrichment Score (NES) | -1.5922978 |
| Nominal p-value | 0.015873017 |
| FDR q-value | 0.21809384 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 496 | 0.183 | 0.0227 | No |
| 2 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 1206 | 0.109 | 0.0054 | No |
| 3 | TAS2R5 | TAS2R5 Entrez, Source | taste receptor, type 2, member 5 | 1562 | 0.091 | 0.0085 | No |
| 4 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 2190 | 0.067 | -0.0165 | No |
| 5 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2350 | 0.063 | -0.0076 | No |
| 6 | GMPR | GMPR Entrez, Source | guanosine monophosphate reductase | 2611 | 0.057 | -0.0083 | No |
| 7 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 2697 | 0.055 | 0.0035 | No |
| 8 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 3287 | 0.043 | -0.0267 | No |
| 9 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | -0.0195 | No |
| 10 | SDCBP | SDCBP Entrez, Source | syndecan binding protein (syntenin) | 4064 | 0.029 | -0.0618 | No |
| 11 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 4150 | 0.028 | -0.0590 | No |
| 12 | CSRP3 | CSRP3 Entrez, Source | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 4369 | 0.024 | -0.0675 | No |
| 13 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 4566 | 0.022 | -0.0751 | No |
| 14 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 4616 | 0.021 | -0.0720 | No |
| 15 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | -0.0921 | No |
| 16 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 5051 | 0.015 | -0.0945 | No |
| 17 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5340 | 0.011 | -0.1127 | No |
| 18 | EPS15 | EPS15 Entrez, Source | epidermal growth factor receptor pathway substrate 15 | 7217 | -0.013 | -0.2493 | No |
| 19 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7318 | -0.014 | -0.2521 | No |
| 20 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.3034 | No |
| 21 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 8925 | -0.036 | -0.3525 | No |
| 22 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 10443 | -0.061 | -0.4464 | No |
| 23 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 10590 | -0.064 | -0.4363 | No |
| 24 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.4220 | No |
| 25 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.4080 | No |
| 26 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11920 | -0.100 | -0.4591 | Yes |
| 27 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 11925 | -0.100 | -0.4266 | Yes |
| 28 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 12042 | -0.105 | -0.4010 | Yes |
| 29 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 12165 | -0.110 | -0.3740 | Yes |
| 30 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 12353 | -0.119 | -0.3491 | Yes |
| 31 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12681 | -0.140 | -0.3277 | Yes |
| 32 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 12731 | -0.144 | -0.2840 | Yes |
| 33 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 12815 | -0.154 | -0.2395 | Yes |
| 34 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12999 | -0.184 | -0.1927 | Yes |
| 35 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 13048 | -0.197 | -0.1317 | Yes |
| 36 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 13106 | -0.211 | -0.0667 | Yes |
| 37 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 13202 | -0.257 | 0.0105 | Yes |
