Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | DER_IFNB_UP |
| Enrichment Score (ES) | -0.4271835 |
| Normalized Enrichment Score (NES) | -1.4994401 |
| Nominal p-value | 0.028639618 |
| FDR q-value | 0.3340291 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 772 | 0.143 | -0.0232 | No |
| 2 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 920 | 0.127 | -0.0031 | No |
| 3 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 1206 | 0.109 | 0.0022 | No |
| 4 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 1327 | 0.103 | 0.0182 | No |
| 5 | TAS2R5 | TAS2R5 Entrez, Source | taste receptor, type 2, member 5 | 1562 | 0.091 | 0.0228 | No |
| 6 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 1588 | 0.090 | 0.0428 | No |
| 7 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1791 | 0.081 | 0.0474 | No |
| 8 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 2190 | 0.067 | 0.0340 | No |
| 9 | HIF3A | HIF3A Entrez, Source | hypoxia inducible factor 3, alpha subunit | 2328 | 0.064 | 0.0392 | No |
| 10 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2350 | 0.063 | 0.0531 | No |
| 11 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 2697 | 0.055 | 0.0406 | No |
| 12 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 3287 | 0.043 | 0.0068 | No |
| 13 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | 0.0105 | No |
| 14 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 3738 | 0.035 | -0.0085 | No |
| 15 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 4150 | 0.028 | -0.0326 | No |
| 16 | CSRP3 | CSRP3 Entrez, Source | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 4369 | 0.024 | -0.0430 | No |
| 17 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 4566 | 0.022 | -0.0525 | No |
| 18 | TEAD1 | TEAD1 Entrez, Source | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 4615 | 0.021 | -0.0511 | No |
| 19 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 4616 | 0.021 | -0.0460 | No |
| 20 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 4892 | 0.017 | -0.0625 | No |
| 21 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | -0.0632 | No |
| 22 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 5091 | 0.014 | -0.0701 | No |
| 23 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 5268 | 0.012 | -0.0805 | No |
| 24 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5340 | 0.011 | -0.0833 | No |
| 25 | AP3M2 | AP3M2 Entrez, Source | adaptor-related protein complex 3, mu 2 subunit | 5555 | 0.007 | -0.0975 | No |
| 26 | EPS15 | EPS15 Entrez, Source | epidermal growth factor receptor pathway substrate 15 | 7217 | -0.013 | -0.2193 | No |
| 27 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 7272 | -0.014 | -0.2199 | No |
| 28 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7318 | -0.014 | -0.2198 | No |
| 29 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 7835 | -0.021 | -0.2534 | No |
| 30 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.2680 | No |
| 31 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 8279 | -0.028 | -0.2738 | No |
| 32 | CTR9 | CTR9 Entrez, Source | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 8385 | -0.029 | -0.2746 | No |
| 33 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 8925 | -0.036 | -0.3063 | No |
| 34 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 9881 | -0.052 | -0.3655 | No |
| 35 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 10443 | -0.061 | -0.3928 | No |
| 36 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10688 | -0.066 | -0.3950 | No |
| 37 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.3868 | No |
| 38 | ELF1 | ELF1 Entrez, Source | E74-like factor 1 (ets domain transcription factor) | 11340 | -0.083 | -0.4070 | Yes |
| 39 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 11566 | -0.088 | -0.4023 | Yes |
| 40 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 11822 | -0.096 | -0.3980 | Yes |
| 41 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11880 | -0.098 | -0.3782 | Yes |
| 42 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11920 | -0.100 | -0.3567 | Yes |
| 43 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 11925 | -0.100 | -0.3326 | Yes |
| 44 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 12042 | -0.105 | -0.3157 | Yes |
| 45 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 12130 | -0.108 | -0.2957 | Yes |
| 46 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 12165 | -0.110 | -0.2714 | Yes |
| 47 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 12268 | -0.115 | -0.2510 | Yes |
| 48 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 12353 | -0.119 | -0.2283 | Yes |
| 49 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12681 | -0.140 | -0.2187 | Yes |
| 50 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 12731 | -0.144 | -0.1871 | Yes |
| 51 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 12815 | -0.154 | -0.1556 | Yes |
| 52 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12999 | -0.184 | -0.1243 | Yes |
| 53 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 13048 | -0.197 | -0.0798 | Yes |
| 54 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 13083 | -0.205 | -0.0322 | Yes |
| 55 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 13106 | -0.211 | 0.0178 | Yes |
