Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | DER_IFNG_UP |
| Enrichment Score (ES) | -0.48620525 |
| Normalized Enrichment Score (NES) | -1.587913 |
| Nominal p-value | 0.025114154 |
| FDR q-value | 0.21681891 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 496 | 0.183 | 0.0173 | No |
| 2 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 772 | 0.143 | 0.0393 | No |
| 3 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 1206 | 0.109 | 0.0394 | No |
| 4 | TAS2R5 | TAS2R5 Entrez, Source | taste receptor, type 2, member 5 | 1562 | 0.091 | 0.0399 | No |
| 5 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1791 | 0.081 | 0.0469 | No |
| 6 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 2190 | 0.067 | 0.0371 | No |
| 7 | HIF3A | HIF3A Entrez, Source | hypoxia inducible factor 3, alpha subunit | 2328 | 0.064 | 0.0459 | No |
| 8 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2350 | 0.063 | 0.0632 | No |
| 9 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 2697 | 0.055 | 0.0538 | No |
| 10 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 3287 | 0.043 | 0.0223 | No |
| 11 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3372 | 0.041 | 0.0283 | No |
| 12 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 3738 | 0.035 | 0.0112 | No |
| 13 | SDCBP | SDCBP Entrez, Source | syndecan binding protein (syntenin) | 4064 | 0.029 | -0.0045 | No |
| 14 | CSRP3 | CSRP3 Entrez, Source | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 4369 | 0.024 | -0.0201 | No |
| 15 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 4646 | 0.020 | -0.0348 | No |
| 16 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4953 | 0.016 | -0.0531 | No |
| 17 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 5051 | 0.015 | -0.0560 | No |
| 18 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 5268 | 0.012 | -0.0688 | No |
| 19 | EIF2B1 | EIF2B1 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 5340 | 0.011 | -0.0710 | No |
| 20 | EPS15 | EPS15 Entrez, Source | epidermal growth factor receptor pathway substrate 15 | 7217 | -0.013 | -0.2080 | No |
| 21 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 7272 | -0.014 | -0.2079 | No |
| 22 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7318 | -0.014 | -0.2070 | No |
| 23 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8111 | -0.025 | -0.2590 | No |
| 24 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 8279 | -0.028 | -0.2633 | No |
| 25 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 8925 | -0.036 | -0.3009 | No |
| 26 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 10590 | -0.064 | -0.4068 | No |
| 27 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 10803 | -0.068 | -0.4023 | No |
| 28 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11920 | -0.100 | -0.4564 | Yes |
| 29 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 11925 | -0.100 | -0.4268 | Yes |
| 30 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 12042 | -0.105 | -0.4043 | Yes |
| 31 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 12165 | -0.110 | -0.3805 | Yes |
| 32 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12333 | -0.118 | -0.3579 | Yes |
| 33 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 12353 | -0.119 | -0.3239 | Yes |
| 34 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 12731 | -0.144 | -0.3091 | Yes |
| 35 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 12815 | -0.154 | -0.2692 | Yes |
| 36 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 12996 | -0.183 | -0.2280 | Yes |
| 37 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12999 | -0.184 | -0.1731 | Yes |
| 38 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 13048 | -0.197 | -0.1178 | Yes |
| 39 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 13106 | -0.211 | -0.0591 | Yes |
| 40 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 13202 | -0.257 | 0.0105 | Yes |
