Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_72h.class.cls
#double_gel_8d_versus_double_gel_72h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_72h_repos
Upregulated in classdouble_gel_8d
GeneSetDIAB_NEPH_DN
Enrichment Score (ES)0.5125446
Normalized Enrichment Score (NES)2.0672379
Nominal p-value0.0
FDR q-value0.0028107276
FWER p-Value0.065
Table: GSEA Results Summary



Fig 1: Enrichment plot: DIAB_NEPH_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 750.9720.0386Yes
2ANXA1ANXA1
Entrez,  Source
annexin A1100.8150.0709Yes
3SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1120.8030.1030Yes
4COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)150.7370.1324Yes
5ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 2190.7070.1605Yes
6LPLLPL
Entrez,  Source
lipoprotein lipase240.6800.1875Yes
7CTGFCTGF
Entrez,  Source
connective tissue growth factor320.6600.2134Yes
8ADMADM
Entrez,  Source
adrenomedullin340.6490.2393Yes
9GPRC5AGPRC5A
Entrez,  Source
G protein-coupled receptor, family C, group 5, member A490.5870.2618Yes
10PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)590.5570.2834Yes
11PRKAR2BPRKAR2B
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type II, beta690.4940.3025Yes
12F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor890.4560.3193Yes
13BMP2BMP2
Entrez,  Source
bone morphogenetic protein 2910.4510.3373Yes
14PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 11140.4080.3520Yes
15CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 21180.4020.3679Yes
16CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 21450.3670.3806Yes
17GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)1960.3240.3897Yes
18TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 32760.2630.3942Yes
19SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 12800.2610.4045Yes
20ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)3380.2340.4095Yes
21PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)3610.2250.4168Yes
22GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 54010.2090.4222Yes
23CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 14090.2070.4300Yes
24F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)4180.2050.4376Yes
25DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 94370.1990.4442Yes
26DPYSL3DPYSL3
Entrez,  Source
dihydropyrimidinase-like 34990.1820.4468Yes
27ADORA1ADORA1
Entrez,  Source
adenosine A1 receptor5470.1730.4502Yes
28TMEM123TMEM123
Entrez,  Source
transmembrane protein 1235510.1720.4568Yes
29CYR61CYR61
Entrez,  Source
cysteine-rich, angiogenic inducer, 615590.1710.4631Yes
30SCRN1SCRN1
Entrez,  Source
secernin 15680.1700.4694Yes
31TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)5770.1680.4755Yes
32PDGFAPDGFA
Entrez,  Source
platelet-derived growth factor alpha polypeptide6190.1620.4789Yes
33COLQCOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase7180.1490.4773Yes
34CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b8580.1330.4721Yes
35CALD1CALD1
Entrez,  Source
caldesmon 19200.1270.4725Yes
36FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)9210.1270.4776Yes
37ACSL3ACSL3
Entrez,  Source
acyl-CoA synthetase long-chain family member 39300.1260.4821Yes
38CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 59760.1230.4836Yes
39RGS10RGS10
Entrez,  Source
regulator of G-protein signalling 1010090.1210.4860Yes
40PLSCR1PLSCR1
Entrez,  Source
phospholipid scramblase 110730.1160.4858Yes
41PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D10880.1160.4894Yes
42DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 110980.1150.4933Yes
43PPFIA4PPFIA4
Entrez,  Source
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 410990.1150.4979Yes
44PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)11160.1140.5012Yes
45LOXL1LOXL1
Entrez,  Source
lysyl oxidase-like 111370.1130.5042Yes
46TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase12500.1070.5000Yes
47TSPAN3TSPAN3
Entrez,  Source
tetraspanin 312540.1070.5041Yes
48CASTCAST
Entrez,  Source
calpastatin12580.1070.5081Yes
49DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112970.1040.5094Yes
50MYO1BMYO1B
Entrez,  Source
myosin IB13110.1040.5125Yes
51COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 413730.1000.5119No
52SULF1SULF1
Entrez,  Source
sulfatase 114700.0950.5084No
53APODAPOD
Entrez,  Source
apolipoprotein D16530.0870.4980No
54TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)16720.0860.5000No
55CAPN2CAPN2
Entrez,  Source
calpain 2, (m/II) large subunit17260.0840.4993No
56SERINC5SERINC5
Entrez,  Source
serine incorporator 518580.0780.4925No
57MYO1EMYO1E
Entrez,  Source
myosin IE19420.0750.4891No
58PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)19750.0740.4896No
59PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1420070.0730.4902No
60TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 520900.0700.4867No
61FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES21180.0690.4875No
62CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor22310.0660.4816No
63ATXN1ATXN1
Entrez,  Source
ataxin 122540.0660.4825No
64ING1ING1
Entrez,  Source
inhibitor of growth family, member 122890.0650.4825No
65PAWRPAWR
Entrez,  Source
PRKC, apoptosis, WT1, regulator24210.0610.4750No
66DDNDDN
Entrez,  Source
dendrin25350.0590.4687No
67SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)25780.0580.4678No
68PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 627340.0540.4582No
69SYNPOSYNPO
Entrez,  Source
synaptopodin28310.0520.4529No
70PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)29020.0510.4496No
71ARL1ARL1
Entrez,  Source
ADP-ribosylation factor-like 129080.0510.4513No
72ALDH3B1ALDH3B1
Entrez,  Source
aldehyde dehydrogenase 3 family, member B129190.0500.4525No
73NPTNNPTN
Entrez,  Source
neuroplastin29250.0500.4542No
74BCAMBCAM
Entrez,  Source
basal cell adhesion molecule (Lutheran blood group)29880.0490.4514No
75PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 130060.0480.4520No
76SKP1ASKP1A
Entrez,  Source
S-phase kinase-associated protein 1A (p19A)32870.0430.4324No
77MSH2MSH2
Entrez,  Source
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)34050.0400.4251No
78PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 134370.0400.4243No
79GTF2A2GTF2A2
Entrez,  Source
general transcription factor IIA, 2, 12kDa36150.0370.4123No
80LITAFLITAF
Entrez,  Source
lipopolysaccharide-induced TNF factor36540.0360.4108No
81ITGB5ITGB5
Entrez,  Source
integrin, beta 537140.0350.4077No
82HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 137900.0340.4033No
83CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 138480.0330.4003No
84GSTA4GSTA4
Entrez,  Source
glutathione S-transferase A439970.0300.3902No
85AIF1AIF1
Entrez,  Source
allograft inflammatory factor 140470.0300.3876No
86ABI1ABI1
Entrez,  Source
abl-interactor 141120.0290.3839No
87OAS1OAS1
Entrez,  Source
2',5'-oligoadenylate synthetase 1, 40/46kDa41500.0280.3822No
88PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform41660.0280.3822No
89TNNT2TNNT2
Entrez,  Source
troponin T type 2 (cardiac)41820.0270.3821No
90PHYHIPPHYHIP
Entrez,  Source
phytanoyl-CoA 2-hydroxylase interacting protein42330.0260.3794No
91RARRES2RARRES2
Entrez,  Source
retinoic acid receptor responder (tazarotene induced) 244070.0240.3671No
92PRDX6PRDX6
Entrez,  Source
peroxiredoxin 644300.0230.3664No
93STX7STX7
Entrez,  Source
syntaxin 744520.0230.3657No
94PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O45110.0220.3621No
95CD164CD164
Entrez,  Source
CD164 molecule, sialomucin46160.0210.3550No
96HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 146550.0200.3530No
97RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family46810.0200.3518No
98CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)46990.0200.3513No
99TMEM23TMEM23
Entrez,  Source
transmembrane protein 2347100.0190.3513No
100TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)47570.0190.3486No
101DNM1LDNM1L
Entrez,  Source
dynamin 1-like47830.0180.3474No
102PDIA3PDIA3
Entrez,  Source
protein disulfide isomerase family A, member 348430.0180.3436No
103CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator48630.0170.3429No
104DPP6DPP6
Entrez,  Source
dipeptidyl-peptidase 649570.0160.3364No
105ACBD3ACBD3
Entrez,  Source
acyl-Coenzyme A binding domain containing 349640.0160.3366No
106WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 149860.0150.3356No
107DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)50070.0150.3347No
108CD47CD47
Entrez,  Source
CD47 molecule50660.0140.3308No
109HMGN3HMGN3
Entrez,  Source
high mobility group nucleosomal binding domain 350920.0140.3295No
110MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1051480.0130.3258No
111VPS26AVPS26A
Entrez,  Source
vacuolar protein sorting 26 homolog A (yeast)51850.0130.3236No
112CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta52680.0120.3178No
113OPTNOPTN
Entrez,  Source
optineurin52990.0110.3159No
114RHOBTB2RHOBTB2
Entrez,  Source
Rho-related BTB domain containing 254500.0090.3049No
115PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase55010.0080.3014No
116CACNB2CACNB2
Entrez,  Source
calcium channel, voltage-dependent, beta 2 subunit55710.0070.2964No
117MTX2MTX2
Entrez,  Source
metaxin 256270.0070.2925No
118AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase56490.0060.2911No
119PFN2PFN2
Entrez,  Source
profilin 257380.0050.2846No
120NBNNBN
Entrez,  Source
nibrin57690.0050.2825No
121GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha57880.0050.2813No
122TBCATBCA
Entrez,  Source
tubulin-specific chaperone a57930.0050.2812No
123HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like58300.0040.2786No
124PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)58530.0040.2771No
125GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 258990.0030.2738No
126RHEBRHEB
Entrez,  Source
Ras homolog enriched in brain59180.0030.2726No
127CMAHCMAH
Entrez,  Source
cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase)59910.0020.2672No
128ATXN10ATXN10
Entrez,  Source
ataxin 1060350.0020.2639No
129PRKCIPRKCI
Entrez,  Source
protein kinase C, iota60410.0020.2636No
130NDNNDN
Entrez,  Source
necdin homolog (mouse)61080.0010.2586No
131TAX1BP1TAX1BP1
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 161360.0000.2566No
132ATP6AP2ATP6AP2
Entrez,  Source
ATPase, H+ transporting, lysosomal accessory protein 26241-0.0010.2487No
133CANXCANX
Entrez,  Source
calnexin6492-0.0040.2298No
134MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase6546-0.0050.2259No
135HSPA5HSPA5
Entrez,  Source
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)6557-0.0050.2254No
136DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)6712-0.0070.2139No
137WT1WT1
Entrez,  Source
Wilms tumor 16748-0.0080.2115No
138TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)6770-0.0080.2102No
139TCF21TCF21
Entrez,  Source
transcription factor 216846-0.0090.2049No
140HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)6866-0.0090.2038No
141NAB1NAB1
Entrez,  Source
NGFI-A binding protein 1 (EGR1 binding protein 1)6874-0.0090.2036No
142NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 16962-0.0100.1974No
143SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 26971-0.0100.1972No
144SACM1LSACM1L
Entrez,  Source
SAC1 suppressor of actin mutations 1-like (yeast)7162-0.0130.1832No
145NPHS1NPHS1
Entrez,  Source
nephrosis 1, congenital, Finnish type (nephrin)7169-0.0130.1832No
146CASP1CASP1
Entrez,  Source
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)7177-0.0130.1832No
147HMGN1HMGN1
Entrez,  Source
high-mobility group nucleosome binding domain 17215-0.0130.1809No
148EPS15EPS15
Entrez,  Source
epidermal growth factor receptor pathway substrate 157217-0.0130.1814No
149PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 17272-0.0140.1778No
150NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 27314-0.0140.1753No
151SEPT2SEPT2
Entrez,  Source
septin 27427-0.0160.1673No
152UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase7435-0.0160.1674No
153CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 27447-0.0160.1672No
154UBE2L6UBE2L6
Entrez,  Source
ubiquitin-conjugating enzyme E2L 67569-0.0180.1587No
155PSMA2PSMA2
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 27610-0.0180.1564No
156MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)7620-0.0180.1565No
157KIF5BKIF5B
Entrez,  Source
kinesin family member 5B7649-0.0190.1551No
158DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 17683-0.0190.1533No
159GYG1GYG1
Entrez,  Source
glycogenin 17708-0.0190.1523No
160CAND2CAND2
Entrez,  Source
cullin-associated and neddylation-dissociated 2 (putative)7711-0.0200.1529No
161NAPGNAPG
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, gamma7833-0.0210.1445No
162GMFBGMFB
Entrez,  Source
glia maturation factor, beta7835-0.0210.1453No
163KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)7846-0.0210.1454No
164ADD3ADD3
Entrez,  Source
adducin 3 (gamma)7901-0.0220.1421No
165SUB1SUB1
Entrez,  Source
SUB1 homolog (S. cerevisiae)7922-0.0220.1415No
166RAD23BRAD23B
Entrez,  Source
RAD23 homolog B (S. cerevisiae)7961-0.0230.1395No
167AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)7975-0.0230.1394No
168GRIK2GRIK2
Entrez,  Source
glutamate receptor, ionotropic, kainate 28215-0.0270.1223No
169YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8261-0.0270.1199No
170TOB1TOB1
Entrez,  Source
transducer of ERBB2, 18322-0.0280.1165No
171YWHAZYWHAZ
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide8338-0.0280.1165No
172PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 58373-0.0290.1150No
173BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 38408-0.0290.1136No
174IRS1IRS1
Entrez,  Source
insulin receptor substrate 18456-0.0300.1113No
175GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase8496-0.0310.1095No
176UNGUNG
Entrez,  Source
uracil-DNA glycosylase8535-0.0310.1079No
177CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)8731-0.0340.0943No
178WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase8852-0.0350.0866No
179NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 98900-0.0360.0845No
180CYP51A1CYP51A1
Entrez,  Source
cytochrome P450, family 51, subfamily A, polypeptide 19103-0.0390.0706No
181HNRPCHNRPC
Entrez,  Source
heterogeneous nuclear ribonucleoprotein C (C1/C2)9106-0.0390.0720No
182PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)9537-0.0460.0410No
183ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 69627-0.0470.0362No
184PLXNB2PLXNB2
Entrez,  Source
plexin B29773-0.0500.0271No
185BIRC2BIRC2
Entrez,  Source
baculoviral IAP repeat-containing 29826-0.0510.0251No
186PTPN11PTPN11
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)9881-0.0520.0231No
187ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29899-0.0520.0239No
188PTPN7PTPN7
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 710142-0.0560.0076No
189PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase10182-0.0560.0069No
190MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 210184-0.0560.0091No
191XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)10199-0.0570.0103No
192PBEF1PBEF1
Entrez,  Source
pre-B-cell colony enhancing factor 110279-0.0580.0066No
193ARHGAP5ARHGAP5
Entrez,  Source
Rho GTPase activating protein 510392-0.0600.0005No
194CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)10417-0.0610.0011No
195ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 610450-0.0610.0011No
196BMP7BMP7
Entrez,  Source
bone morphogenetic protein 7 (osteogenic protein 1)10568-0.064-0.0053No
197GLULGLUL
Entrez,  Source
glutamate-ammonia ligase (glutamine synthetase)10574-0.064-0.0031No
198VEGFVEGF
Entrez,  Source
vascular endothelial growth factor10686-0.066-0.0090No
199DDX17DDX17
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1710688-0.066-0.0064No
200UBE2D2UBE2D2
Entrez,  Source
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)10785-0.068-0.0110No
201LANCL1LANCL1
Entrez,  Source
LanC lantibiotic synthetase component C-like 1 (bacterial)10788-0.068-0.0084No
202STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa10803-0.068-0.0067No
203PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa10816-0.069-0.0049No
204EXOSC7EXOSC7
Entrez,  Source
exosome component 710861-0.070-0.0055No
205RAI14RAI14
Entrez,  Source
retinoic acid induced 1410917-0.071-0.0068No
206CYP1B1CYP1B1
Entrez,  Source
cytochrome P450, family 1, subfamily B, polypeptide 110964-0.073-0.0074No
207RDXRDX
Entrez,  Source
radixin11042-0.074-0.0103No
208IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa11121-0.076-0.0132No
209FNBP1FNBP1
Entrez,  Source
formin binding protein 111225-0.079-0.0179No
210CSDACSDA
Entrez,  Source
cold shock domain protein A11295-0.081-0.0199No
211SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)11419-0.084-0.0259No
212NFASCNFASC
Entrez,  Source
neurofascin homolog (chicken)11534-0.087-0.0311No
213RAB21RAB21
Entrez,  Source
RAB21, member RAS oncogene family11632-0.090-0.0349No
214UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 211694-0.092-0.0359No
215NMINMI
Entrez,  Source
N-myc (and STAT) interactor11925-0.100-0.0494No
216SLKSLK
Entrez,  Source
STE20-like kinase (yeast)12099-0.107-0.0584No
217TAPBPTAPBP
Entrez,  Source
TAP binding protein (tapasin)12109-0.108-0.0547No
218PODXLPODXL
Entrez,  Source
podocalyxin-like12132-0.109-0.0521No
219AGRINAGRIN
Entrez,  Source
agrin12183-0.111-0.0514No
220PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)12232-0.113-0.0506No
221XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)12235-0.113-0.0462No
222BST2BST2
Entrez,  Source
bone marrow stromal cell antigen 212353-0.119-0.0504No
223GNEGNE
Entrez,  Source
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase12371-0.119-0.0469No
224GPNMBGPNMB
Entrez,  Source
glycoprotein (transmembrane) nmb12406-0.122-0.0446No
225ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1512561-0.132-0.0511No
226MECP2MECP2
Entrez,  Source
methyl CpG binding protein 2 (Rett syndrome)12612-0.135-0.0495No
227EXOC7EXOC7
Entrez,  Source
exocyst complex component 712695-0.141-0.0501No
228GHRGHR
Entrez,  Source
growth hormone receptor12744-0.146-0.0479No
229KLK7KLK7
Entrez,  Source
kallikrein 7 (chymotryptic, stratum corneum)12860-0.160-0.0503No
230DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12862-0.160-0.0439No
231AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1112961-0.175-0.0444No
232TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2313053-0.198-0.0434No
233PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)13079-0.204-0.0372No
234TSPYL4TSPYL4
Entrez,  Source
TSPY-like 413090-0.207-0.0296No
235HNRPA1HNRPA1
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A113096-0.208-0.0217No
236MCM6MCM6
Entrez,  Source
MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)13114-0.214-0.0144No
237GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 113181-0.242-0.0097No
238FGFR2FGFR2
Entrez,  Source
ffer syndrome, Jackson-Weiss syndrome)13200-0.255-0.0009No
239OTUD4OTUD4
Entrez,  Source
OTU domain containing 413243-0.2910.0076No
Table: GSEA details [plain text format]



Fig 2: DIAB_NEPH_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: DIAB_NEPH_DN: Random ES distribution   
Gene set null distribution of ES for DIAB_NEPH_DN