Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_72h.class.cls #double_gel_8d_versus_double_gel_72h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_72h_repos |
| Upregulated in class | double_gel_72h |
| GeneSet | DNA_REPLICATION |
| Enrichment Score (ES) | -0.41482574 |
| Normalized Enrichment Score (NES) | -1.4162278 |
| Nominal p-value | 0.05733945 |
| FDR q-value | 0.46567786 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 560 | 0.171 | 0.0146 | No |
| 2 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 1554 | 0.091 | -0.0297 | No |
| 3 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 1934 | 0.075 | -0.0333 | No |
| 4 | REPIN1 | REPIN1 Entrez, Source | replication initiator 1 | 1999 | 0.073 | -0.0138 | No |
| 5 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 2991 | 0.049 | -0.0722 | No |
| 6 | EREG | EREG Entrez, Source | epiregulin | 2999 | 0.049 | -0.0566 | No |
| 7 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 3405 | 0.040 | -0.0736 | No |
| 8 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 4080 | 0.029 | -0.1147 | No |
| 9 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 4217 | 0.027 | -0.1160 | No |
| 10 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 4310 | 0.025 | -0.1146 | No |
| 11 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 5466 | 0.009 | -0.1985 | No |
| 12 | NBN | NBN Entrez, Source | nibrin | 5769 | 0.005 | -0.2196 | No |
| 13 | TBRG1 | TBRG1 Entrez, Source | transforming growth factor beta regulator 1 | 6314 | -0.002 | -0.2598 | No |
| 14 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 6442 | -0.004 | -0.2681 | No |
| 15 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 6476 | -0.004 | -0.2693 | No |
| 16 | GLI1 | GLI1 Entrez, Source | glioma-associated oncogene homolog 1 (zinc finger protein) | 6483 | -0.004 | -0.2683 | No |
| 17 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 6859 | -0.009 | -0.2936 | No |
| 18 | PTMS | PTMS Entrez, Source | parathymosin | 7316 | -0.014 | -0.3231 | No |
| 19 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 7417 | -0.016 | -0.3254 | No |
| 20 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 7512 | -0.017 | -0.3269 | No |
| 21 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7792 | -0.021 | -0.3410 | No |
| 22 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 8076 | -0.025 | -0.3542 | No |
| 23 | KCTD13 | KCTD13 Entrez, Source | potassium channel tetramerisation domain containing 13 | 8102 | -0.025 | -0.3477 | No |
| 24 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 8125 | -0.025 | -0.3409 | No |
| 25 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8883 | -0.036 | -0.3859 | No |
| 26 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 9014 | -0.038 | -0.3832 | No |
| 27 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 9201 | -0.040 | -0.3838 | No |
| 28 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 9276 | -0.041 | -0.3756 | No |
| 29 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 9386 | -0.043 | -0.3694 | No |
| 30 | GTPBP4 | GTPBP4 Entrez, Source | GTP binding protein 4 | 9786 | -0.050 | -0.3829 | No |
| 31 | IGHMBP2 | IGHMBP2 Entrez, Source | immunoglobulin mu binding protein 2 | 10212 | -0.057 | -0.3959 | Yes |
| 32 | MUTYH | MUTYH Entrez, Source | mutY homolog (E. coli) | 10230 | -0.057 | -0.3782 | Yes |
| 33 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 10373 | -0.060 | -0.3691 | Yes |
| 34 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10927 | -0.072 | -0.3869 | Yes |
| 35 | WRNIP1 | WRNIP1 Entrez, Source | Werner helicase interacting protein 1 | 11093 | -0.076 | -0.3742 | Yes |
| 36 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 11274 | -0.081 | -0.3610 | Yes |
| 37 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 11368 | -0.083 | -0.3403 | Yes |
| 38 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 11626 | -0.090 | -0.3299 | Yes |
| 39 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11707 | -0.092 | -0.3053 | Yes |
| 40 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12141 | -0.109 | -0.3017 | Yes |
| 41 | TFAM | TFAM Entrez, Source | transcription factor A, mitochondrial | 12152 | -0.109 | -0.2661 | Yes |
| 42 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12174 | -0.110 | -0.2310 | Yes |
| 43 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12175 | -0.110 | -0.1943 | Yes |
| 44 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12677 | -0.140 | -0.1856 | Yes |
| 45 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12737 | -0.145 | -0.1419 | Yes |
| 46 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 12763 | -0.148 | -0.0946 | Yes |
| 47 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13022 | -0.190 | -0.0510 | Yes |
| 48 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 13154 | -0.226 | 0.0141 | Yes |
